GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMTCR1 939 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human thymocyte mRNA for T-cell antigen receptor chain (86T1)
ACCESSION X00438
KEYWORDS T-cell receptor; constant region; joining region; leader peptide;
variable region.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 939)
AUTHORS Hedrick,S.M., Nielsen,E.A., Kavaler,J., Cohen,D.I. and Davis,M.M.
TITLE Sequence relationships between putative T-cell receptor
polypeptides and immunoglobulins
JOURNAL Nature 308, 153-158 (1984)
STANDARD full automatic
COMMENT From EMBL entry HSTCR1; dated 03-JAN-1991.
FEATURES Location/Qualifiers
misc_feature 1..22
/note="5' untranslated region"
CDS 23..79
/note="(aa 1-19)"
/product="put. leader peptide"
/codon_start=23
CDS 80..373
/note="(aa 20-117)"
/product="put. variable region"
/codon_start=80
misc_feature 128..136
/note="poss. CHO attachment site"
misc_feature 245..253
/note="poss. CHO attachment site"
CDS 374..421
/note="(aa 118-133)"
/product="put. joining region"
/codon_start=374
misc_feature complement(375..767)
/note="poss. CHO attachment site"
CDS 422..>939
/note="(aa 134-306) (939 is 2nd base in codon)"
/product="put. constant region fragment"
/codon_start=422
misc_feature 434..442
/note="poss. CHO attachment site"
misc_feature 620..628
/note="poss. CHO attachment site"
BASE COUNT 242 a 237 c 237 g 223 t
ORIGIN
1 ccgtctggag cctgattcca ccatgagctg caggcttctc ctctatgttt ccctatgtct
61 tgtggaaaca gcactcatga acactaaaat tactcagtca ccaagatatc taatcttggg
121 aagagcaaat aagtctttgg aatgtgagca acatctggga cataatgcta tgtactggta
181 taaacagagc gctgagaagc cgccagagct catgtttctc tacaatctta aacagttgat
241 tcgaaatgag acggtgccca gtcgttttat acctgaatgc ccagacagct ccaagctact
301 tttacatata tctgccgtgg atccagaaga ctcagctgtc tatttttgtg ccagcagcca
361 cggacagggg gtttctggaa atacgctcta ttttggagaa ggaagccggc tcattgttgt
421 agaggatctg agaaatgtga ctccacccaa ggtctccttg tttgagccat caaaagcaga
481 gattgcaaac aaacaaaagg ctaccctcgt gtgcttggcc aggggcttct tccctgacca
541 cgtggagctg agctggtggg tgaatggcaa ggaggtccac agtggggtca gcacggaccc
601 tcaggcctac aaggagagca attatagcca ctgcctgagc agccgcctga gggtctctgc
661 taccttctgg cacaatcctc gcaaccactt ccgctgccaa gtgcagttcc atgggctttc
721 agaggaggac aagtggccag agggctcacc caaacctgtc acacagaaca tcagtgcaga
781 ggcctggggc cgagcagact gtgggattac ctcagcatcc tatcaacaag gggtcttgtc
841 tgccaccatc ctctatgaga tcctgctagg gaaagccacc ctgtatgctg tgcttgtcag
901 tacactggtg gtgatggcta tggtcaaaag aaagaattc
//