GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMMBPX1 1791 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human MBP gene for myelin basic protein, exon 1
ACCESSION X17286
KEYWORDS myelin; myelin basic protein; structural protein.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1791)
AUTHORS Hofmann,K.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 1791)
AUTHORS Streicher,R. and Stoffel,W.
TITLE The Organization of the Human Myelin Basic Protein Gene -
Comparison with the Mouse Gene
JOURNAL Biol. Chem. Hoppe-Seyler 370, 503-510 (1989)
STANDARD full automatic
COMMENT *source: library=pcos2 EMBL, Charon 4A; clone=MBPNterm, MBPCterm;
**map: chromosome=18; See X17286, X17287, X17290, X17288, X17369
and X17289, respectivly for myelin basic protein gene exons 1-7.
See also <J04746> for MBP gene exon 1.
Data kindly reviewed (20-JUN-1990) by Hofmann K.
From EMBL entry HSMBPX1; dated 06-JUL-1990.
FEATURES Location/Qualifiers
precursor_RNA 1169..>1791
/note="primary transcript"
mRNA 1352..1528
/note="exon 1"
CDS 1352..1528
/note="myelin basic protein (AA 1-59)"
/codon_start=1352
intron 1529..>1791
/note="intron I"
BASE COUNT 475 a 371 c 512 g 433 t
ORIGIN
1 tatgtgtatg gaatggatgg atagatggat ggatgagtaa atgactatat gtggatggat
61 ggatgcatga gtggatggat ggatgagtgg atagatggag gggtgggtgg atgggtgaac
121 ggatggatga gtggatgggg gatggatgga tgcatggatg gatggatggg taggtgggtg
181 tgtgtatgga tggatggata gatggatgga tgggtaaatg gactgttatg tggatggatg
241 gatggatgga tagagagata gatggatgac tggtattaca gggatatgtg agtgaatcct
301 gttttctgta gataagtaat agagtttgga gaggaaacta actaaatgat atttatttaa
361 acctaacact ctaacttgaa agcaaaatgg attcattgcc cttcgtgaca gaaatgtggt
421 attttttgga gaaagctatg agatgctggt atacaacatg aaatatctca atcccacttc
481 agatttctaa ttgtttctgc ttccagagga gaagccaagt caaaatgtcc tgaataagca
541 gttctctatt gtgagaggcc tcttgtggaa tctgggattg aaacaattct aaatgcccca
601 cttctttcat gcatgaattg caaaaagatg tggcaagttt tgtttctacc aagaaaacta
661 aaaacacctt ttgtcaaata aatgctcctt gcatatttaa cttatgcacc agtggccttt
721 taaacagtca atgtcccatc aaggtgcctg cacatctggg ctctccggga gcagccatgg
781 cagcacccgg gaagaaacgc tgatgtggct gctctgcatg ctcagatgac ttcatcggga
841 agcctgggtg cattttacgc tgggtgccaa atctgagtaa ctgaggaatt cccagagcct
901 tctgaaacac agagctgcaa taaggctgct ccatccaggt tagctccatc ctaggccaag
961 ggctttatga ggactgcaca tattctgtgg gttttatagg agacagctag gtcaagaccc
1021 ctcagagaaa gctgctttgt ccggtgctca gctttgcaca ggcccgtatt catatctcat
1081 tgttgtttgc aggagaggca gatgcgaacc agaacaatgg gacctcctct caggacacag
1141 cggtgactga ctccaagcgc acagcggacc cgaagaatgc ctggcaggat gccacccagc
1201 tgacccaggg agccgccccc acttgatccg cctcttttcc cgagatgccc cggggaggga
1261 ggacaacacc ttcaaagaca ggccctctga gtccgacgag ctccagacca tccaagaaga
1321 cagtgcagcc acctccgaga gcctggatgt gatggcgtca cagaagagac cctcccagag
1381 gcacggatcc aagtacctgg ccacagcaag taccatggac catgccaggc atggcttcct
1441 cccaaggcac agagacacgg gcatccttga ctccatcggg cgcttctttg gcggtgacag
1501 gggtgcgccc aagcggggct ctggcaaggt gagctctgag gagtagagga gttttagttt
1561 aaatggaaaa agcaaaggag aaatcagtag gtgaactcag ccattagagg aagaactggc
1621 acgtagcctc ttgctgtcta aggtctcgtt ccgtgctgga gaatgcatat gagcccaaga
1681 gtgtgggcct gagaggctgc ttaggacgtt ttcgtttaac tcaccccctc ttttcctcac
1741 aagggatggt ggccggggtg tggctcagga atgtaaggac atgctgaatt c
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