GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMTCRAR 1508 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for T-cell receptor alpha chain (TCR-alpha)
ACCESSION X02592
KEYWORDS T-cell receptor; T-cell receptor alpha; membrane protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1508)
AUTHORS Rabbitts,T.H., Lefranc,M.P., Stinson,M.A., Sims,J.E., Schroder,J.,
Steinmetz,M., Spurr,N.L., Solomon,E. and Goodfellow,P.N.
TITLE The chromosomal location of T-cell receptor genes and a T-cell
rearranging gen: possible correlation with specific translocations
in humna T-cell leukaemia
JOURNAL EMBO J. 4, 1461-1465 (1985)
STANDARD full automatic
COMMENT From EMBL entry HSTCRAR; dated 03-JAN-1991.
FEATURES Location/Qualifiers
CDS 129..959
/note="(aa 1-277)"
/product="TCR-alpha chain"
/codon_start=129
misc_feature 468..485
/note="pot. variable region (aa 114-119)"
misc_feature 486..533
/note="pot. joining region (aa 120-135)"
misc_feature 534..959
/note="pot. constant region (aa 136-277)"
misc_feature 1492..1497
/note="pot. polyA signal"
BASE COUNT 344 a 431 c 341 g 392 t
ORIGIN
1 ttttgaaacc cttcaaaggc agagacttgt ccagcctaac ctgcctgctg ctcctagctc
61 ctgaggctca gggcccttgg cttctgtccg ctctgctcag ggccctccag cgtggccact
121 gctcagccat gctcctgctg ctcgtcccag tgctcgaggt gatttttacc ctgggaggaa
181 ccagagccca gtcggtgacc cagcttggca gccacgtctc tgtctctgaa ggagccctgg
241 ttctgctgag gtgcaactac tcatcgtctg ttccaccata tctcttctgg tatgtgcaat
301 accccaacca aggactccag cttctcctga agtacacatc agcggccacc ctggttaaag
361 gcatcaacgg ttttgaggct gaatttaaga agagtgaaac ctccttccac ctgacgaaac
421 cctcagccca tatgagcgac gcggctgagt acttctgtgc tgtgagtgat ctcgaaccga
481 acagcagtgc ttccaagata atctttggat cagggaccag actcagcatc cggccaaata
541 tccagaaccc tgaccctgcc gtgtaccagc tgagagactc taaatccagt gacaagtctg
601 tctgcctatt caccgatttt gattctcaaa caaatgtgtc acaaagtaag gattctgatg
661 tgtatatcac agacaaaact gtgctagaca tgaggtctat ggacttcaag agcaacagtg
721 ctgtggcctg gagcaacaaa tctgactttg catgtgcaaa cgccttcaac aacagcatta
781 ttccagaaga caccttcttc cccagcccag aaagttcctg tgatgtcaag ctggtcgaga
841 aaagctttga aacagatacg aacctaaact ttcaaaacct gtcagtgatt gggttccgaa
901 tcctcctcct gaaagtggcc gggtttaatc tgctcatgac gctgcggctg tggtccagct
961 gagatctgca agattgtaag acagcctgtg ctccctcgct ccttcctctg cattgcccct
1021 cttctccctc tccaaacaga gggaactctc ctacccccaa ggaggtgaaa gctgctacca
1081 cctctgtgcc cccccggtaa tgccaccaac tggatcctac ccgaatttat gattaagatt
1141 gctgaagagc tgccaaacac tgctgccacc ccctctgttc ccttattgct gcttgtcact
1201 gcctgacatt cacggcagag gcaaggctgc tgcagcctcc cctggctgtg cacattccct
1261 cctgctcccc agagactgcc tccgccatcc cacagatgat ggatcttcag tgggttctct
1321 tgggctctag gtcctggaga atgttgtgag gggtttattt ttttttaata gtgttcataa
1381 agaaatacat agtattcttc ttctcaagac gtggggggaa attatctcat tatcgaggcc
1441 ctgctatgct gtgtgtctgg gcgtgttgta tgtcctgctg ccgatgcctt cattaaaatg
1501 atttggaa
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