GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMTK5G 4274 bp ds-DNA PRI 30-MAY-1991
DEFINITION Human gene for thymidine kinase, 5' region (EC 2.7.1.21)
ACCESSION X15509
KEYWORDS kinase; thymidine kinase.
SOURCE Homo sapiens DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4274)
AUTHORS Sauve,G.J.
JOURNAL Unpublished (1989)
STANDARD full automatic
REFERENCE 2 (bases 1 to 4274)
AUTHORS Sauve,G.J., Lipson,K.E., Chen,S.T. and Baserga,R.
TITLE Sequence analysis of the human thymidine kinase gene promoter:
comparison with the human PCNA promoter.
JOURNAL DNA Sequence 1, 13-23 (1990)
STANDARD full automatic
COMMENT *source: tissue=blood; cell type=T cell; *source: cell line=acute
lymphocytic leukemia; library=EMBL3 *source: clone=pTK8KS; *map:
chromosome=17; map position=q23-q25; See <M13643> for overlapping
sequence.
From EMBL entry HSTK5G; dated 29-NOV-1990.
BASE COUNT 1119 a 1147 c 1094 g 914 t
ORIGIN
1 cctgcaggct cgactgctag gcacggttgt gacctccccc ggacctctcc tgcctccagt
61 agtccctgca gcaaggggtc ctggcaccct gccctggagc tgggaggttt ataaagtgcc
121 tggtgtttgg gaaatgcccc tcgaggccca ggtggtgcag cacagccccc ccaaccccca
181 gcattctgaa tcactgccac atgcttaagg acacccaatg cggccacgga gaggtcacac
241 tagtaccttc aattcctatc tgtgagtagg tcctaaggct tcctctgctc ccagtcggac
301 aaccacgctg ggacagtact gattctacca gctcctgcag ggcacaaaca tgaggctccg
361 taagaacttt ccttctcaac gagtgtcccc tccccctcgc ccatgcccgg ctgctcctct
421 ctgccttaga agccctcgcc ccagtatccc agggtctcca agatgccctg agatccatgg
481 tctagaggta taccagcgac cgctgtgcct ttagccagct ggcagcctta agggagatga
541 ggtccccaaa cgaattccag ttaatgccat acatgggcac cactcccaca gcagttacga
601 ccaggggagg ccaggtgccc ggtggctcac gccctgtaat cctagcactt tgggagcctg
661 aggtggatca cttgaagtca gaagtttgag ccgagacctg gccaacatgg caaaacccca
721 tctctactga aaacaaaact agaagagcgt ggtggtgtgc acctgtaatc ccagctactt
781 gggaggctga ggagaattgc ttaagcctgg gaggtggagg ttcgagtgag ccgagatctc
841 gaccactgca ctccagccta gcgacagagc aagactctac ctcaaaaaaa ttaaaaaagg
901 aggagctgat ctgcgctgag agggtgcgat tctgaccaca ggaggtcaca gcacagtcaa
961 aggcacagag gtgaggagga aggaatgaaa ggtcagtttg caaattctgg caggccctat
1021 ggctgacaca cagaggtgag gctgggaggt ctgggctgga ggtaggaggt ctgtgaatgt
1081 ctgctaacac cttcacactt tatgcagaaa gtaacaagga accattctga ggcagtttgg
1141 agaattaaaa aaagaaaaaa aaaaaacaga ggcagggctg gggggggggc tcacgccctg
1201 taatcccagc acttgggagg cccaggccgc acacgaaaaa aaggagttca agatcagcct
1261 gacacatcag atgaaaaccc catttctact aaaaatacaa aaattaacca ggcatggtgg
1321 accccctgta atcccagcta ctcaggaggc tgaagcagga gaatagcttg aaccagggag
1381 gcagaggttc agtgagccgg gatcatgcta ctgcactcca gcctgggcga cagagtgaga
1441 ccccatctca aaaaaaaaaa aaaaaaaacc aacagaaaat gctggacacg gtcgtctcgc
1501 ctgtaatccc agccatttgg gaggccaaga taggcagatc acttgactcc aggagttcca
1561 gaccagtctg ggcaatatgg cgaaacacta tctctacgaa aatatgaaaa aatcaaccgg
1621 gcatggtggt ggactactct gtagtcctag ctattcggga ggctaggcag gagcaatggc
1681 ttgagcccag gaagcagaga gacttgtagc tgagccaaga ttgcgccatt gcactccagc
1741 cctgagagag caaaaccctg tttcaaaaaa aaaaaaaaaa caaaacactg ggcgtggtgg
1801 ctcacacctg taatcccagc actttgggag gctgaggcgg gtgaatcacc tgaggtcagg
1861 agttcgacac catcctggcc aacatggtga aactccgtct ctctactaaa aatacaaaaa
1921 ttgactgggc atggtggccg gggccgtaat ctcagctact cgggaggctg aggcaggaga
1981 atcgctggaa ctcgggaggt ggaggttgca gcgagctgag atcccaccat tgcactctag
2041 cctgggtgca caacagcgag actccatctc aaaaaaaaaa aaaaaaaaaa gtaacaagga
2101 accagatttg aagaaagggc tcttttccat catgagaaat gggaagtcag ggcagcctca
2161 tggcaaggcc tgaggtcaaa tgccatctga cctccctcac ttagttactg ttttatcctc
2221 aacaagttac ttagtctctg agattcagtt tcctgactgg tagaaggtat ctatccaggg
2281 gggggcaaac agtggctgca cacctgtgac gtgctcagca ctttgggagg ccgagggccg
2341 ggtggatcac ttgaggccag gagttcgaag accagtctgt ccaacatgga cgaaacccca
2401 tctctattaa aaatacaaaa attggccagg cgcagtggct catgcctgta aacccagcac
2461 tttgggaggc caaggggggc ggatcatgag gtcaggagtt ggagaccatc ctcggtaaca
2521 cagtgaaacc ccatctctac taaaaataca aaaaaattag ccgggcatgg ttgcgggcgc
2581 atgtagtccc agctactcag gaggctgagg ccggagaatg gcgtgaaccc tggaagaaga
2641 ggttgcagtg agcccagatc gcgccactcg actccagcca gtgggcagta gagcgagact
2701 ctgtctcaaa agaaaaaaaa aaaaaattag ccaggcagta gtaccagcta cagtgtgcct
2761 gtaatcccag ccactgggag gctgaggcag gagaatcact tgaacccggg aggtagttcc
2821 agtaagccga gatcatacca ctgcactcca gcctgggtga ctgaccagac tgtgttctca
2881 aaaaaagaag gcatgtatcc aaatcacaag gttaaaagag ataaagcatg cgagtaaaat
2941 aaagcaagcc agtcagtcag tgtgggttgc ttcttcctcc cagtgaagag ctctttgtca
3001 gaggtccttg gatctgtcca atctctgtac ctggaaaggt tataccttgt aggatcctta
3061 cacgccacct ggcacactct gtgatcactg ccaccacctc tttgttgcta tatttatgat
3121 catgattatc atgggtttct tttctttctt tctttttttt tttgagccac cgcacccgcc
3181 tgtatgtttc taaccttcac aaccccaatg taaataccag ctgttctgaa tccttcagcc
3241 tgtgccacat aagcacagac ccaaaaacat tgtgtaacct cagatcaagg tccagaactt
3301 tgtgccctaa cctcctgcgg gtctatggat tttttttttt tttttttttt tttttttttt
3361 ttgagactaa gtcttggtct atcgcccagc cttccaggct ggagtacaaa atggcaatga
3421 tctcggctca ctggtgcaaa cctccacctc ctgggttcaa gcgattctcc tgtctcagcc
3481 tccccagtag ctggttacag aggtacatca ccaccgcccg gctaattttt gtatttttag
3541 tagaaacggg gtttcaccat gttggccagg ctggtctcga actcctgacc tcgtgatccg
3601 caaagtgcat aggattacag gtgtgacgcc gccacgcctg gcagggtcta cggatattat
3661 tagcatagtc aggacttcaa ttttctttat cctgaaaacc aggttaacaa aaatccttag
3721 gagaaggtaa aatacaccat ggtgctcaag cactggggac ctggcatcgc actaggcgct
3781 ctgcatgccc acaggagtgc tctagacggc ttctaagctt ccttcttgga attccaaact
3841 aataaatgag ctaactccgc cccagcccct tagtccctcc ctgcaatcca cctacctctg
3901 cagacatctt cttccaagga accttgcttg ggaaacccac accagacaca tccatcatgg
3961 cgtctacagc cgcatgggcg tgcgtccctc tgtttatatg gccagagccc cgcctcgctc
4021 cgccccttta aacttggtgg gcggaccgag gcggggctca gaccaggccc caccccgatc
4081 agccacgtcc atcgccctga tttccaggcc ctcccagtcc ctgggcgcac gtcccggatt
4141 cctcccacga gggggcgggc tgcggccaaa tctcccgcca ggtcagcggc cggggctgat
4201 tggcccccat ggcggcgggg ccggctcgtg attggccagc acgccgtggt ttaaagcggt
4261 cggcgggaac cagg
//