GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMTYRRP 2837 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA for tyrosinase-related protein
ACCESSION X51420
KEYWORDS melanosomal protein, tyrosinase-related protein.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2837)
AUTHORS Shibahara,S.
JOURNAL Unpublished (1990)
STANDARD full automatic
REFERENCE 2 (bases 1 to 2837)
AUTHORS Cohen,T., Muller,R.M., Tomita,Y. and Shibahara,S.
TITLE Nucleotide sequence of the cDNA human tyrosinase-related protein
JOURNAL Nucleic Acids Res. 18, 2807-2807 (1990)
STANDARD full automatic
COMMENT SWISS-PROT; P17643; TYRR$HUMAN.
*source: cell line=S7 human melanoma cells;
From EMBL entry HSTYRRP; dated 28-NOV-1990.
FEATURES Location/Qualifiers
precursor_RNA 1..2512
/note="primary transcript"
CDS 130..1710
/note="pre propeptide (AA -24 to 503)"
/codon_start=130
CDS 130..201
/note="signal peptide (AA -24 to -1)"
/codon_start=130
CDS 202..1710
/note="mature tyrosinase-related protein (AA 1-503)"
/codon_start=202
BASE COUNT 823 a 591 c 552 g 871 t
ORIGIN
1 aattctaaga gaagttcatc agagacatcc ttcaggattg tgagctggat tttcctctac
61 gtgcttcagt cttctctaca caaagagctg caaaccaggt ctttgttttg cactcttatt
121 tcaagcagaa tgagtgctcc taaactcctc tctctgggct gtatcttctt ccccttgcta
181 ctttttcagc aggcccgggc tcaattccca agacagtgtg ccactgttga ggctttgaga
241 agtggtatgt gttgcccaga cctgtcccct gtgtctgggc ctgggacaga ccgctgtggc
301 tcatcatcag ggaggggcag atgtgaggca gtgactgcag actcccggcc ccacagccct
361 cagtatcccc atgatggcag agatgatcgg gaggtctggc ccttgcgctt cttcaatagg
421 acatgtcact gcaacggcaa tttctcagga cacaactgtg ggacgtgccg tcctggctgg
481 agaggagctg cctgtgacca gagggttctc atagtcagga gaaatcttct ggacttaagt
541 aaagaagaaa agaaccactt tgtccgggcc ctggatatgg caaagcgcac aactcaccct
601 ttatttgtca ttgccaccag gagatcagaa gaaatactgg ggccagatgg caacacgcca
661 caatttgaga acatttccat ttataactac tttgtttgga cacactatta ctcagtcaaa
721 aagactttcc ttggggtagg acaggaaagc tttggtgaag tggatttctc tcatgaggga
781 ccagcttttc tcacatggca caggtaccac ctcctgcgtc tggagaaaga catgcaggaa
841 atgttgcaag agccttcttt ctcccttcct tactggaatt ttgcaacggg gaaaaatgtc
901 tgtgatatct gcacggatga cttgatggga tccagaagca actttgattc cactctaata
961 agcccaaact ctgtcttttc tcaatggcga gtggtctgtg actccttgga agattatgat
1021 accctgggaa cactttgtaa cagcaccgag gatgggccaa ttaggagaaa tccagctgga
1081 aatgtggcca gaccaatggt gcaacgtctt cctgaaccac aggatgtcgc tcagtgcttg
1141 gaagttggtt tatttgacac gcctcctttt tattccaact ctacaaacag tttccgaaac
1201 acagtggaag gttacagtga ccccacggga aagtatgacc ctgctgttcg aagtcttcac
1261 aatttggctc atctattcct gaatggaaca gggggacaaa cccatttgtc tccaaatgat
1321 cctatttttg tcctcctgca caccttcaca gatgcagtct ttgatgaatg gctgaggaga
1381 tacaatgctg atatatccac atttccattg gaaaatgccc ctattggaca taatagacaa
1441 tacaacatgg tgccattctg gcccccagtc accaacacag aaatgtttgt tactgctcca
1501 gacaacctgg gatacactta tgaaattcaa tggccaagtc gggagtttag tgtacctgag
1561 ataattgcca tagcagtagt tggcgctttg ttactggttg cactcatttt tgggactgct
1621 tcttatctga ttcgtgccag acgcagtatg gatgaagcta accagcctct cctcactgat
1681 cagtatcaat gctatgctga agaaagaata tgaaaaactc cagaatccta atcagtctgt
1741 ggtctaacaa atgccctact ctcttatgca ttagtatcac aaaaccacct ggttgaatat
1801 aatagattga gttattaact gtattttctt tcactttatt accttctttc taatacaagc
1861 atatgttagc attaaagttc taggcatact tttcaaagct gggaagaccc tttcagaatc
1921 ttttcaatgg gttttaattt tcagttctat ttaaaatggt gaatgacact aaactccatg
1981 atatttaagg atagtgtgaa gatctttggc atgatttaaa ggttgagtat gtgaagatat
2041 aagtgaacta ccatgctttg tttacgtgta aaggaaaata atgtttgata gtaaatgtcc
2101 acttaaaata catgaatggg catttctaaa atgttaaaac ataaacacat ttccattcat
2161 ggatatttgt caacagattt aaagaaaacc acagttatta attaaagaaa attaattatg
2221 tgtagttata aaccaatgaa attttgatta accttttcaa attaatgttc cagtttgaag
2281 accaatcaaa tatattattt agtcaacata tactatttag tctcaggttc aaggctacaa
2341 caaaaatcac catctttgtc aaactttgga gagggaaaat cttcactttc ttaagcaaca
2401 atggatattg cctgtgtttg ccactgtgtt tccctgcctc tcaattcgct gaaaaaggaa
2461 ctacctatcc ttacatttca cctactaatg tctcttctaa catcttagag gtccatggag
2521 aaggcatatg gagaacatgt tttatactgc tctataaata gtattccaat cactgtgctt
2581 aatttaaata gcattatctt atcatttatc agccttttat gtattttcca agtaaaatat
2641 taacatatta tttcattggt cttctttttt atctggttct atatgaatgc tattttttcc
2701 cttctcttct aacatgaaat atattttctc tttttgatct tgtgctatga aacaatctta
2761 ccaaagaact gtataaggtg gtcataagtg aatattttaa ttaaaattgg taaaaataaa
2821 aaaaaaaaaa taaaaat
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