GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMTHR1 1947 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human mRNA encoding prothrombin.
ACCESSION V00595
KEYWORDS complementary DNA; signal peptide; thrombin.
SOURCE Homo sapiens RNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1947)
AUTHORS Friezner,d.S.J., MacGillivray,R.T. and Davie,E.W.
TITLE Characterization of the complementary deoxyribonucleic acid and
gene coding for human prothrombin
JOURNAL Biochemistry 22, 2087-2097 (1983)
STANDARD full automatic
COMMENT SWISS-PROT; P00734; THRB$HUMAN.
Data kindly reviewed (15-JUL-1983) by Degen S.J. Friezner
From EMBL entry HSTHR1; dated 06-JUL-1989.
FEATURES Location/Qualifiers
mRNA 1..1947
/note="messenger RNA"
CDS 3..1847
/note="prothrombin"
/codon_start=3
polyA_site 1947..1947
/note="polyA addition site"
BASE COUNT 439 a 522 c 609 g 377 t
ORIGIN
1 tgcagctgcc tggctgcctg gccctggctg ccctgtgtag ccttgtgcac agccagcatg
61 tgttcctggc tcctcagcaa gcacggtcgc tgctccagcg ggtccggcga gccaacacct
121 tcttggagga ggtgcgcaag ggcaacctag agcgagagtg cgtggaggag acgtgcagct
181 acgaggaggc cttcgaggct ctggagtcct ccacggctac ggatgtgttc tgggccaagt
241 acacagcttg tgagacagcg aggacgcctc gagataagct tgctgcatgt ctggaaggta
301 actgtgctga gggtctgggt acgaactacc gagggcatgt gaacatcacc cggtcaggca
361 ttgagtgcca gctatggagg agtcgctacc cacataagcc tgaaatcaac tccactaccc
421 atcctggggc cgacctacag gagaatttct gccgcaaccc cgacagcagc aacacgggac
481 cctggtgcta cactacagac cccaccgtga ggaggcagga atgcagcatc cctgtctgtg
541 gccaggatca agtcactgta gcgatgactc cacgctccga aggctccagt gtgaatctgt
601 cacctccatt ggagcagtgt gtccctgatc gggggcagca gtaccagggg cgcctggcgg
661 tgaccacaca tgggctcccc tgcctggcct gggccagcgc acaggccaag gccctgagca
721 agcaccagga cttcaactca gctgtgcagc tggtggagaa cttctgccgc aacccagacg
781 gggatgagga gggcgtgtgg tgctatgtgg ccgggaagcc tggcgacttt gggtactgcg
841 acctcaacta ttgtgaggag gccgtggagg aggagacagg agatgggctg gatgaggact
901 cagacagggc catcgaaggg cgtaccgcca caagtgagta ccagactttc ttcaatccga
961 ggacctttgg ctcgggagag gcagactgtg ggctgcgacc tctgttcgag aagaagtcgc
1021 tggaggacaa aaccgaaaga gagctcctgg aatcctacat cgacgggcgc attgtggagg
1081 gctcggatgc agagatcggc atgtcacctt ggcaggtgat gcttttccgg aagagtcccc
1141 aggagctgct gtgtggggcc agcctcatca gtgaccgctg ggtcctcacc gccgcccact
1201 gcctcctgta cccgccctgg gacaagaact tcaccgagaa tgaccttctg gtgcgcattg
1261 gcaagcactc ccgcaccagg tacgagcgaa acattgaaaa gatatccatg ttggaaaaga
1321 tctacatcca ccccaggtac aactggcggg agaacctgga ccgggacatt gccctgatga
1381 agctgaagaa gcctgttgcc ttcagtgact acattcaccc tgtgtgtctg cccgacaggg
1441 agacggcagc cagcttgctc caggctggat acaaggggcg ggtgacaggc tggggcaacc
1501 tgaaggagac gtggacagcc aacgttggta aggggcagcc cagtgtcctg caggtggtga
1561 acctgcccat tgtggagcgg ccggtctgca aggactccac ccggatccgc atcactgaca
1621 acatgttctg tgctggttac aagcctgatg aagggaaacg aggggatgcc tgtgaaggtg
1681 acagtggggg accctttgtc atgaagagcc cctttaacaa ccgctggtat caaatgggca
1741 tcgtctcatg gggtgaaggc tgtgaccggg atgggaaata tggcttctac acacatgtgt
1801 tccgcctgaa gaagtggata cagaaggtca ttgatcagtt tggagagtag ggggccactc
1861 atattctggg ctcctggaac caatcccgtg aaagaattat ttttgtgttt ctaaaactat
1921 ggttcccaat aaaagtgact ctcagcg
//