GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMIGHHIVB 429 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human IgH anti-HIV1 antibody mRNA, VDJ-region.
ACCESSION M67501
KEYWORDS anti-HIV1 antibody; diversity exon; immunoglobulin heavy chain;
joining exon; variable region.
SOURCE Human adult blood B-cell, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 429)
AUTHORS Andris,J.S., Johnson,S., Zolla-Pazner,S. and Capra,J.D.
TITLE Molecular characterization of five human anti-HIV-1 antibody heavy
chains reveals extensive somatic mutation typical of an antigen-
immune response
JOURNAL Proc. Natl. Acad. Sci. U.S.A. (1991) In press
STANDARD full staff_entry
FEATURES Location/Qualifiers
sig_peptide complement(1..57)
/gene="IgH"
/codon_start=57
CDS 1..429
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=1
/partial
mat_peptide 58..429
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=58
/partial
BASE COUNT 81 a 128 c 116 g 104 t
ORIGIN
1 atgaaacacc tgtggttctt cctcctcctg gtggcagctc ccagatgggt actgtcccag
61 gtgctactac aggagtcggg cccaggactg gtgaagcctt cacaggccct gtccctcacc
121 tgtagtgtct ctgggggctc cgtcagtggc actaattatt attggagttg gatccggcag
181 cccgccggga agggactgga gtggattggc cgtatctatt ctactgggac caccgccttc
241 aaccccgccc tcaagggtcg atccaccatt tcagtagaca cgtccaagac caagttcttc
301 ctgagactga cgtctgtgac ccgcgcagac acggccactt atttctgtgc cagagtcacg
361 ttgacaagtc gagttgtagg tcgttacttt gactcatggg gccagggact cctggtcacc
421 gtctcctca
//GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMIGHHIVC 411 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human IgH anti-HIV1 antibody mRNA, VDJ-region.
ACCESSION M67502
KEYWORDS anti-HIV1 antibody; diversity exon; immunoglobulin heavy chain;
joining exon; variable region.
SOURCE Human adult blood B-cell, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 411)
AUTHORS Andris,J.S., Johnson,S., Zolla-Pazner,S. and Capra,J.D.
TITLE Molecular characterization of five human anti-HIV-1 antibody heavy
chains reveals extensive somatic mutation typical of an antigen-
immune response
JOURNAL Proc. Natl. Acad. Sci. U.S.A. (1991) In press
STANDARD full staff_entry
FEATURES Location/Qualifiers
sig_peptide complement(1..57)
/gene="IgH"
/codon_start=57
CDS 1..411
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=1
/partial
mat_peptide 58..411
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=58
/partial
BASE COUNT 81 a 109 c 130 g 91 t
ORIGIN
1 atggactgga cctggaggat cttctgcttg ctggctgtag ctccaggtgc tcagtcccag
61 gtgcagctgc tgcagtctgg ggctgaggtg aggaagcctg gggcctcagt gaaaatttcc
121 tgcaagccat ctggcttctc cttcatcacc tactattttc actgggtgcg acaggccccc
181 ggacaggggc ttgagtggat gggagtaatc aaccctagtg gtggcacaac ctactcacag
241 aagttccagg gcagagtcgc catgaccagg gacacgtcca cgagcgcagt gtacatggag
301 ttgagcagcc tgagatctgt agacacggcc atatattact gtgctggagt tcagggggtg
361 gcccggcctt taggggactg gggccaggga tccctggtca ccgtctcctc a
//GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS HUMIGHHIVD 366 bp ss-mRNA PRI 30-MAY-1991
DEFINITION Human IgH anti-HIV1 antibody mRNA, VDJ-region.
ACCESSION M67503
KEYWORDS anti-HIV1 antibody; diversity exon; immunoglobulin heavy chain;
joining exon; variable region.
SOURCE Human adult blood B-cell, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 366)
AUTHORS Andris,J.S., Johnson,S., Zolla-Pazner,S. and Capra,J.D.
TITLE Molecular characterization of five human anti-HIV-1 antibody heavy
chains reveals extensive somatic mutation typical of an antigen-
immune response
JOURNAL Proc. Natl. Acad. Sci. U.S.A. (1991) In press
STANDARD full staff_entry
FEATURES Location/Qualifiers
CDS 1..366
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=1
/partial
mat_peptide 1..366
/product="anti-HIV1 antibody"
/gene="IgH"
/codon_start=1
/partial
BASE COUNT 81 a 101 c 101 g 83 t
ORIGIN
1 caggtgcagt tgcaggtgtc gggcccagga ctggtgaagc cttcggagac cctgtccctc
61 acctgcactg tctctggtgg ccccatcaat aatgcctact ggacatggat ccgacagccc
121 ccagggaagg ggctagagta ccttggatat gtctatcata ctggagtcac caactacaat
181 ccctccctca agagccggct caccataaca atagacacgt ccaggaagca gttatccctc
241 agcctgaagt ttgtgaccgc tgcggactcg gccgtatatt attgtgcgag agagtgggcc
301 gaggatggtg acttcggaaa tgcttttcat gtctggggcc aagggacaat ggtcgctgtc
361 tcttca
//