GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS PPH16E 1154 bp ss-mRNA VRL 30-MAY-1991
DEFINITION Human papillomavirus type 16 mRNA.
ACCESSION D00735
KEYWORDS E1-E4 fusion protein; E6 protein; E7 protein; integration.
SOURCE Human papillomavirus type 16, cDNA to mRNA from keratinocyte line
SK-v cells, clone 1A.
ORGANISM Human papillomavirus
Viridae; ds-DNA nonenveloped viruses; Papovaviridae;
Papillomavirus.
REFERENCE 1 (bases 1 to 1154)
AUTHORS Schneider-Maunoury,S., Pehau-Arnaudet,G., Breitburd,F. and Orth,G.
TITLE Expression of the human papillomavirus type 16 genome in SK-v
cells , a line derived from a vulvar intraepithelial neoplasia
JOURNAL J. Gen. Virol. 71, 809-817 (1990)
STANDARD full staff_review
FEATURES Location/Qualifiers
CDS <1..63
/note="E6 protein"
misc_feature 1..1
/note="position 173 of the prototype genome"
misc_feature 54..54
/note="splice donor site at position 226 of the prototype
genome"
misc_feature 55..55
/note="splice acceptor site at position 409 of the
prototype genome"
CDS 208..504
/note="E7 protein"
CDS 511..789
/note="E1-E4 fusion protein"
misc_feature 527..527
/note="splice donor site at position 880 of the prototype
genome"
misc_feature 528..528
/note="splice acceptor site at position 3358 of the
prototype genome"
variation 579..579
/note="t in cDNA clone 1A; c in prototype clone at
position 3410"
cellular 802..1154
/note="cellular DNA"
repeat_region 802..1055
/note="Alu repeat"
misc_signal 1142..1147
/note="polyadenylation signal"
BASE COUNT 348 a 282 c 245 g 279 t
ORIGIN 331 bp upstream of PvuII site.
1 catgatataa tattagaatg tgtgtactgc aagcaacagt tactgcgacg tgaggtgtat
61 taactgtcaa aagccactgt gtcctgaaga aaagcaaaga catctggaca aaaagcaaag
121 attccataat ataaggggtc ggtggaccgg tcgatgtatg tcttgttgca gatcatcaag
181 aacacgtaga gaaacccagc tgtaatcatg catggagata cacctacatt gcatgaatat
241 atgttagatt tgcaaccaga gacaactgat ctctactgtt atgagcaatt aaatgacagc
301 tcagaggagg aggatgaaat agatggtcca gctggacaag cagaaccgga cagagcccat
361 tacaatattg taaccttttg ttgcaagtgt gactctacgc ttcggttgtg cgtacaaagc
421 acacacgtag acattcgtac tttggaagac ctgttaatgg gcacactagg aattgtgtgc
481 cccatctgtt ctcagaaacc ataatctacc atggctgatc ctgcagcagc aacgaagtat
541 cctctcctga aattattagg cagcacttgg ccaaccactc cgccgcgacc cataccaaag
601 ccgtcgcctt gggcaccgaa gaaacacaga cgactatcca gcgaccaaga tcagagccag
661 acaccggaaa cccctgccac accactaagt tgttgcacag agactcagtg gacagtgctc
721 caatcctcac tgcatttaac agctcacaca aaggacggat taactgtaat agtaacacta
781 cacccatagt acatttaaaa ggctggaagc agtggcatta tcacatctca ctgcagccct
841 gaaatccccg ctcaagccat ccttccacgt cagcctcctg tgtagctggg accacaggtg
901 tacgccacca caactggtga atttttatat tttttgtaga gatggggatc tctctatgtt
961 gcccaggctg atcttgaact cctgggctca agagatcctc ccacctcagc ctcccaaagt
1021 gctgggatta caggtgtgag ccaccacgcc tggcctcctg ctatcattaa ataaagtaga
1081 aatgatttgt tgctgctaac ttccaaattt ctattagttc atgggagtaa aatttacgca
1141 gaataaatat attt
//