GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS RATCP11BA 2824 bp ss-mRNA ROD 30-MAY-1991
DEFINITION Rat mRNA for cytochrome P-450 11beta, aldo (EC 1.14.15.4).
ACCESSION D00567
KEYWORDS cytochrome P-450 11-beta.
SOURCE Rat (strain Sprague Dawley) adrenal gland, cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2824)
AUTHORS Matsukawa,N., Nonaka,Y., Ying,Z., Higaki,J., Ogihara,T. and
Okamoto,M.
TITLE Molecular cloning and expression of cDNAs encoding rat aldosterone
synthase: variants of cytochrome P-450 11beta
JOURNAL Biochem. Biophys. Res. Commun. 169, 245-252 (1990)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by:
Mitsuhiro Okamoto
Department of Molecular Physiological Chemistry
Osaka University Medical School
4-3-57, Nakanoshima, Kita-ku
Osaka 530
Japan
Phone: 06-443-5531 x253
Email: a62520a@ccsun01.center.osaka-u.ac.jp
Fax: 06-443-6430
FEATURES Location/Qualifiers
CDS 75..1607
/note="cytochrome P-450 11beta, aldo precursor"
sig_peptide 75..176
/note="cytochrome P-450 11beta, aldo signal peptide"
mat_peptide 177..1604
/note="cytochrome P-450 11beta, aldo mature protein"
misc_signal 2776..2781
/note="polyadenylation signal"
BASE COUNT 732 a 678 c 753 g 661 t
ORIGIN
1 aattccatgt agttctcatc accctcactg ttcttagggg ggccgggcat gttcagtagg
61 accaggcggg catcatggga gcgtgtgaca atgacttcat tgagcttcac agcagggtga
121 cagcagatgt gtggctggca agaccctggc agtgcctgca caggacgagg gcactgggca
181 ctacggcaac actggcccct aagacactga agccctttga agccatacca caatactcca
241 ggaacaagtg gctgaagatg atacagatcc tgagggagca gggccaagag aacctacacc
301 tggagatgca ccaggccttc caggagctgg ggcccatttt caggcacagt gcagggggag
361 cacagattgt gtctgtgatg ctgcctgagg acgctgagaa gctgcaccag gtggagagta
421 tcctcccgcg tcggatgcac ctggagccgt gggtggccca cagggaactc cgtggcctga
481 gacgtggtgt gttcttgcta aatggggctg aatggcgctt caaccgactg aaactgaacc
541 caaacgtgct gtcaccaaaa gctgttcaaa attttgtccc catggtggac gaggtagcaa
601 gggacttctt ggaggccctg aaaaagaagg tgcgtcagaa tgctcgaggg agccttacca
661 tggatgtcca gcaaagtctc ttcaactaca ctatagaagc cagcaacttt gcactttttg
721 gagagaggct gggcctcctt ggtcatgacc tgaaccctgg tagcctgaag ttcatccatg
781 ccctacattc aatgttcaag tccaccacac agctcctgtt cttacccaga agcttgactc
841 gctggacaag cacccaggtg tggaaagaac attttgatgc ctgggatgtc atctctgagt
901 atgccaacag atgtatctgg aaggtgcacc aggaactcag actcggcagc tctcagacct
961 acagtggcat tgtggcagca ctaataactc agggagcttt acctctggac gccatcaaag
1021 ccaactctat ggagctcact gctgggagcg ttgacacgac agcaatcccc ttggtaatga
1081 cactttttga gctggctcgg aacccagatg ttcagcaggc cctgcggcag gagaccctgg
1141 cagctgaggc cagcatcgct gctaatcccc agaaggccat gtcagacctg cccttgctgc
1201 gggctgccct taaagagacc ttgagactct accctgttgg tggctttttg gagagaatcc
1261 taaactcaga cctggtgctt cagaactatc atgtccctgc tgggacgttg gtcctacttt
1321 atctgtactc catgggccga aaccctgcag tgttcccaag acctgagcgc tatatgcctc
1381 agcgctggct ggagaggaaa aggagtttcc agcatctggc cttcggcttt ggggtgcgcc
1441 agtgcctggg gcggcgcctg gcagaggtgg agatgctgct cctgcttcac catatgctga
1501 aaaccttcca ggtggagaca ctgagacaag aggatgtgca gatggcctat cgctttgttt
1561 tgatgcccag ctctagtcct gtcctcactt tccggcccat cagctagtca ccttacatct
1621 ggggccctaa tcagtccacc ggcctacttc tgtcctgacg cccaaggtca cgcttctctg
1681 ccagcagaaa tcttgggggg gggaagaggt cacattgtca tcattcaaca caactgtaca
1741 cagtttacag ctgaagacct ccagcatcag gtacaagcaa ggccagggaa gagattagga
1801 gtatcttcag ggcaataggt agtctctcct gagcggtctt ccccattctt tccaacggtc
1861 actccaggtg gccacggcct tcaaagggtc tcagagtaaa gccagaagta atctcctcct
1921 tatggatcca ttattttgac atgacccaca aaaacatttt cacacacaga tgggtttttg
1981 gggggcaaaa gatacataga tgatagatat gatatatgat attgatagat agatagatga
2041 tagatagata gatagataga tagatagata gatagataga tagatagata gatgatggat
2101 gaccagtcat ttatgtctgt gttttgtttg aagcctttca cagtggagct ggcacatatg
2161 agttggtgac tctacagtgt tttaagagta gacacagctg cacttgctaa ggactgggtg
2221 gttgtggtat cagagatgca ggcaggagga cctgctggaa cccagatagt gtgtgaagtc
2281 cccacaggga cggtggtctt ccatgaggtc aaggtgtttt cctgacttct gccagtgcat
2341 gctgcttggg caaaggtaat tctcttgact tgtgaaagtg gcccaaagca taagaatttt
2401 ttcaggtatc ctttcagctg caagtcggta gggcgaaaag ttttggccaa gaacaaccac
2461 ttcacaggat ctcctgtgct cagcaccaaa gcacaaatct actggagatg tgtgtgccaa
2521 attccaaggt cttaggcctt tgagtgtgag gcagtataga gtcagggcct ttaatgatat
2581 aattcgtgtg aaatgagatt actgggttgt gcctactcca atgcccagag agcacccaag
2641 aagagagtga ggtgccaggt cacagagaca gaccccatgt ggaagacagg aagtcagact
2701 tctgtaagcc gaggaaagca gttggaactc ctgtagtctt ggctccatca ctcaatcact
2761 tccctggctg tgaaaaataa acttgtgttg ttgaaaaaaa aaaaaaaaaa aaaaaaaaaa
2821 aaaa
//