GenBank-Updates@genbank.bio.net (05/30/91)
LOCUS RATCP11BV 2705 bp ss-mRNA ROD 30-MAY-1991 DEFINITION Rat mRNA for cytochrome P-450 11beta, variant (EC 1.14.15.4). ACCESSION D00568 KEYWORDS cytochrome P-450 11-beta. SOURCE Rat (strain Sprague Dawley) adrenal gland, cDNA to mRNA. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 2705) AUTHORS Matsukawa,N., Nonaka,Y., Ying,Z., Higaki,J., Ogihara,T. and Okamoto,M. TITLE Molecular cloning and expression of cDNAs encoding rat aldosterone synthase: variants of cytochrome P-450 11beta JOURNAL Biochem. Biophys. Res. Commun. 169, 245-252 (1990) STANDARD full staff_entry COMMENT These data kindly submitted in computer readable form by: Mitsuhiro Okamoto Department of Molecular Physiological Chemistry Osaka University Medical School 4-3-57, Nakanoshima, Kita-ku Osaka 530 Japan Phone: 06-443-5531 x253 Email: a62520a@ccsun01.center.osaka-u.ac.jp Fax: 06-443-6430 FEATURES Location/Qualifiers CDS 5..1507 /note="cytochrome P-450 11beta, variant precursor" sig_peptide 5..76 /note="cytochrome P-450 11beta, variant signal peptide" mat_peptide 77..1504 /note="cytochrome P-450 11beta, variant mature protein" misc_signal 2676..2681 /note="polyadenylation signal" BASE COUNT 692 a 654 c 724 g 635 t ORIGIN 1 ggcaatggct ctcagggtga cagcagatgt gtggctggca agaccctggc agtgcctgca 61 caggacgagg gcactgggca ctacggcaac actggcccct aagacactga agccctttga 121 agccatacca caatactcca ggaacaagtg gctgaagatg atacagatcc tgagggagca 181 gggccaagag aacctacacc tggagatgca ccaggccttc caggagctgg ggcccatttt 241 caggcacagt gcagggggag cacagattgt gtctgtgatg ctgcctgagg acgctgagaa 301 gctgcaccag gtggagagta tcctcccgcg tcggatgcac ctggagccgt gggtggccca 361 cagggaactc cgtggcctga gacgtggtgt gttcttgcta aatggggctg aatggcgctt 421 caaccgactg aaactgaacc caaacgtgct gtcaccaaaa gctgttcaaa attttgtccc 481 catggtggac gaggtagcaa gggacttctt ggaggccctg aaaaagaagg tgcgtcagaa 541 tgctcgaggg agccttacca tggatgtcca gcaaagtctc ttcaactaca ctatagaagc 601 cagcaacttt gcactttttg gagagaggct gggcctcctt ggtcatgacc tgaaccctgg 661 tagcctgaag ttcatccatg ccctacattc aatgttcaag tccaccacac agctcctgtt 721 cttacccaga agcttgactc gctggacaag cacccaggtg tggaaagaac attttgatgc 781 ctgggatgtc atctctgagt atgccaacag atgtatctgg aaggtgcacc aggaactcag 841 actcggcagc tctcagacct acagtggcat tgtggcagca ctaataactc agggagcttt 901 acctctggac gccatcaaag ccaactctat gaagctcact gctgggagcg ttgacacgac 961 agcaatcccc ttggtaatga cactttttga gctggctcgg aacccagatg ttcagcaggc 1021 cctgcggcag gagaccctgg cagctgaggc cagcatcgct gctaatcccc agaaggccat 1081 gtcagacctg cccttgctgc gggctgccct taaagagacc ttgagactct accctgttgg 1141 tggctttttg gagagaatcc taaactcaga cctggtgctt cagaactatc atgtccctgc 1201 tgggacgttg gtcctacttt atctgtactc catgggccga aaccctgcag tgttcccaag 1261 acctgagcgc tatatgcctc agcgctggct ggagaggaaa aggagtttcc agcatctggc 1321 cttcggcttt ggggtgcgcc agtgcctggg gcggcgcctg gcagaggtgg agatgctgct 1381 cctgcttcac catatgctga aaaccttcca ggtggagaca ctgagacaag aggatgtgca 1441 gatggcctat cgctttgttt tgatgcccag ctctagtcct gtcctcactt tccggcccat 1501 cagctagtca ccttacatct ggggccctaa tcagtccacc ggcctacttc tgtcctgacg 1561 cccaaggtca cgcttctctg ccagcagaaa tcttgggggg gggaagaggt cacattgtca 1621 tcattcaaca caactgtaca cagtttacag ctgaagacct ccagcatcag gtacaagcaa 1681 ggccagggaa gagattagga gtatcttcag ggcaataggt agtctctcct gagcggtctt 1741 ccccattctt tccaacggtc actccaggtg gccacggcct tcaaagggtc tcagagtaaa 1801 gccagaagta atctcctcct tatggatcca ttattttgac atgacccaca aaaacatttt 1861 cacacacaga tgggtttttg gggggcaaaa gatacataga tgatagatat gatatatgat 1921 attgatagat agatagatga tagatagata gatagataga tagatagata gatagataga 1981 tagatagata gatgatggat gaccagtcat ttatgtctgt gttttgtttg aagcctttca 2041 cagtggagct ggcacatatg agttggtgac tctacagtgt tttaagagta gacacagctg 2101 cacttgctaa ggactgggtg gttgtggtat cagagatgca ggcaggagga cctgctggaa 2161 cccagatagt gtgtgaagtc cccacaggga cggtggtctt ccatgaggtc aaggtgtttt 2221 cctgacttct gccagtgcat gctgcttggg caaaggtaat tctcttgact tgtgaaagtg 2281 gcccaaagca taagaatttt ttcaggtatc ctttcagctg caagtcggta gggcgaaaag 2341 ttttggccaa gaacaaccac ttcacaggat ctcctgtgct cagcaccaaa gcacaaatct 2401 actggagatg tgtgtgccaa attccaaggt cttaggcctt tgagtgtgag gcagtataga 2461 gtcagggcct ttaatgatat aattcgtgtg aaatgagatt actgggttgt gcctactcca 2521 atgcccagag agcacccaag aagagagtga ggtgccaggt cacagagaca gaccccatgt 2581 ggaagacagg aagtcagact tctgtaagcc gaggaaagca gttggaactc ctgtagtctt 2641 ggctccatca ctcaatcact tccctggctg tgaaaaataa acttgtgttg ttgaaaaaaa 2701 aaaaa //