Slocum@HI-MULTICS.ARPA (12/17/85)
Left-handed sugars cannot be metabolized because the enzyme that metabolizes sugar (Sucrase) is right-handed and won't fit into left-handed sucrose (Sinister sucrose?? :-) . The taste buds are not chemically asymetrical, so either left- or right- handed sugars taste sweet. Enzymes are like putting gloves on the wrong hand, whereas taste buds are like putting socks on the "wrong" foot. Brett Slocum Slocum@HI-MULTICS.ARPA
rsf@Shasta.ARPA (12/18/85)
OK, my big question now is: does left-handed sucrose promote tooth decay? (I'm sorry that this has nothing to do with "space" anymore, but "enquiring minds want to know".) Ross Finlayson Stanford CS Dept. ARPA: rsf@su-pescadero.ARPA UUCP: ...!{decwrl,ucbvax}!Glacier!Shasta!rsf
michaelm@3comvax.UUCP (Michael McNeil) (01/01/86)
In article <1598@Shasta.ARPA> rsf@Shasta.UUCP (Ross Finlayson) writes: >OK, my big question now is: does left-handed sucrose promote tooth decay? >(I'm sorry that this has nothing to do with "space" anymore, but "enquiring >minds want to know".) > >Ross Finlayson >Stanford CS Dept. >ARPA: rsf@su-pescadero.ARPA >UUCP: ...!{decwrl,ucbvax}!Glacier!Shasta!rsf I read recently (sorry, I don't remember where) that tooth decay results from particular species of bacteria which consume sugar in the mouth and then secrete an acid which attacks the teeth. Other species of bacteria eat sugar without secreting this acid. A proclivity towards tooth decay results from which species of bacteria one is infected with (usually from the mother) early in life. Tooth decay is therefore a kind of "ecological" disease. This being the case, presumably bacteria as well as humans use enzymes which are specific to the handedness of sugar. Bacteria which tried to eat left-handed sugar would starve or at least wouldn't have the energy to secrete acid which attacks the teeth. -- Michael McNeil 3Com Corporation "All disclaimers including this one apply" (415) 960-9367 ..!ucbvax!hplabs!oliveb!3comvax!michaelm And with an awful, dreadful list Towards other galaxies unknown Ponderously turns the Milky Way ... Boris Pasternak
bl@hplabsb.UUCP (01/01/86)
> Left-handed sugars cannot be metabolized because the enzyme that > metabolizes sugar (Sucrase) is right-handed and won't fit into > left-handed sucrose (Sinister sucrose?? :-) . The taste buds are not > chemically asymetrical, so either left- or right- handed sugars taste > sweet. Enzymes are like putting gloves on the wrong hand, whereas taste > buds are like putting socks on the "wrong" foot. Are you sure about this? The sense of smell can detect the difference between optical (i.e., left and right handed) isomers. While a left and right handed sugar may both taste sweet, do they taste the same? Probably, since taste can only detect sweet, sour, bitter, and salty.