[sci.virtual-worlds] SArticle#3: Biochips N' Human/Computer Interface

almquist@brahms.udel.edu (Squish) (04/23/91)

Here is the THIRD article in a continual string of HOT info about the
potential, better yet, the inevidable growth of VR.  I have been 
receiving positive responses to my article reviews - if anyone out
there has an info and/or articles, please share with the rest of us!

The article "Biochip Revolution" by Kathleen McAuliffe, 1981 discusses
how we are pushing the silicon limit (or will be VERY SHORTLY!).  Now
that silicon is almost tapped out, whats next?  How about biochips.
NO, you aren't dreaming.  Research has been done and is BEING done on
biochips.  These implants will mesh directly with the human nervous
system, biochip implants may restore sight to the blind, hearing to the
deaf, replace spinal nerves, increase human memory beyond belief, 
increase ones mental capacity (how about adding MIPS to your brain (-:).

Sound like science fiction?  Well, as of 1981 a small company in
Rockville, MD (yeah!  my home town!) known as EMV Associates have been
working on this potential AMAZING techno-breakthrough!  According to
them, "Our aim is to build a computer that can design and assemble
itself by using the same mechanism common to all living things.  This
mechanism is the coding of genetic information in the self-replicating
DNA Double helix and the translation of this chemical code into the
structure of protein."  In addition, an individual eqipped with a
biochip implant could survive after the host has perished.  This
implant could then be moved to an awaiting host - immortality anyone?
Bethesda Research Laboratories, DNA Science INC, E.F. Hutton, Paribas
(a French financial firm), and Mitsui Corporation have all becoming
primary funding parties for EMV Associates.  This is not a flash in
the frying pan outfit.  In addition to these funders, EMV has also
been awarded a grant from the National Science Foundation to test the
first living interface between an electrode-studded chip and the brain.
The article states that "a little over a decade ago (that would make
it late 1960s) British scientists reported that a blind woman could
see phosphenes, bright flashes of light, when they touched her exposed
brain with an electrified wire.  Since then, there has been work
enabling blind patients to see shapes, letter, and even short sentences
in Braille.  Impressive?  At EMV, they're hope is to produce an image
with roughly the resolution of a staticky black-and-white TV.  The
major stumbling block has been the electrodes that are needed to
stimulate the brain.  Electrodes are currently TOO big - instead of
exciting a neuron, they stimulate bundles of neurons due to the
compartive sizes (ie. electrodes are mucho bigger).  EMV "intends to
cover the electrodes with a layer of protein, drilling thousands of
holes through the coating with an electron beam.  The holes will be
covered with polylysine, a cellular glue, and be attached to
embryonic brain neurons.  According to plan, the nervers on the
implanted electrode will then grow into the visual cortex of the brain,
forming links with individual neurons in the patient's cortex."
Each electrode will produce up to 100,000 phosphenes, 6 million in
all.  Kinda like mounting a tiny video screen on your brain - you'd
wear glasses that would in essence be a video camera.  The camera
would plug into you head (I love saying that "plug into you head"!).
According to the article, if all goes well, EMV expects to have a
prototype to test in ten years.  Well, the article was written in
1981 - its now 1991.  According to MY math, thats about ten years.
So, where is it?

EMV in 1981 did work on a pilot study.  Using a coated glass slide
with a monolayer of protein and a protective material known as a
resist, an electron beam was used to dig trenches about half the
width of a red blood cell - similar to cutting silicon.  This was
then dipped into a silver solution that created fine streaks of
microscopic wires.  This work was done by Dr. Jacob Hanker of
the University of North Carolina, in Chapel Hill.  Thus, the 
feasibility of a microchip/biochip was born.  Using this concept,
we can now venture into 3-dimensions.  "They (biochips) open up
the possibility of three-dimensional circuits, increased speed,
reduced energy consumption, and ultraminiaturization that can
reach a million billion elements per cubic centimeter.  On this
scale, all the memory elements of EVERY computer manufactured
TO THIS DAY (1981) could be contained in a cube one centimeter
on a side."  Think you might be able to squeeze this into your
brain?  In addition to EMV, Genex Corporation, Chapel Hill, and
the Naval Research Laboratory in MD are working on making biochips
a reality.

SO, does anyone have any further information about any research
going on in this field?  I've reviewed an article about how to
do sound in VR using a neurophone, how to do tactile feedback
using the simple mechanism used to read text, and now, we know
how to link the brain to a computer.  I think we all can see the 
potential of these devices for mankind and VR.  Hmmmm, maybe 
Gibson and his wetware weren't too far fetched?

- Mike Almquist (almquist@brahms.udel.edu)

Now all we need is the software to use all these wonderful devices!