[misc.handicap] Injectable NSAIDs

Stuart.Ray@f1000.n261.z1.fidonet.org (Stuart Ray) (03/16/91)

Index Number: 13996

[This is from the Chronic Pain Conference on Fidonet]

 DJ> > cures". My husband, a Pharmacy Technician, discovered that
 DJ> > there are injectable anti-inflammatories that totally bypass
 DJ> > consider trying them on me: he claims they are only approved
 DJ> > for "in-patient" hospital use. I know how to give every kind

 DJ> I had heard of them, however am in the same position you are.  Am kept on
 DJ> narcotics, in fact,  have to take them,  and yet if I could take the
 DJ> injectables possible could get away from these pain pills(which I hate)
 DJ> and go back to a productive life, at least if the injectables worked.  I
 DJ> had heard good things about them.

I believe that the drug you are referring to is ketorolac tromethamine
(Toradol) which is given by IM injection.  You are right that it is presently
only licensed for in-hospital use.  I have found that it is effective in
patients who cannot take meds by mouth, but not substantially better than oral
NSAIDs in those who can, although there seems to be something appealing about
an injection for pain control.  The side effects are about the same as other
NSAIDs, including GI upset and ulcers, since these are mediated primarily by
systemic NSAID effects rather than local irritation.
     The bottom line is that it's yet another example of the same old thing in
another package, although the drug reps would (or will) argue with this if
they read it.  Hope this helps.
  -- Stuart

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