Tony.Thoennes@p0.f80.n382.z1.fidonet.org (Tony Thoennes) (05/24/91)
Index Number: 15807
Just done reading a copy of the News Release and it indicates good
news but not as good as I was led to believe when I did my previous
post.. the following is excerpts from the release..
Tucson, Az, may 16, 91 - Researchers sponsored by MDA announced
today that they have located the position of the gene responsible
for one form of ALS..
The international research team reported in todays issue of the New
England Journal of Medicine that the Gene for FAMILIAL ALS is
located in a certain region of Chromosome 21, one of 46 rodlike
structures containing the human genes, the basic units of heredity.
This finding holds tremendous promise for everyone affected by ALS,
said MDA VP and Ex Dir Robert Ross..
The MDA team, headed by Dr. Teapu Siddique, used a method called
linkage analysis to find the Chromosome holding the ALS gene.
Siddique was formely at Duke Univ and now is Assoc Professor and Dir
of Research at the Dept of Neurology, Northwestern Univ Medical
School in Chicago.
This method allowed us to "Link" known genetic segments, called
markers, to a region where the gene we're seeking is located,
Siddique said. After checking more than 100 markers, the
researchers found four markers on chromosome 21 that were linked
with the ALS Gene, he said.
Although most cases of ALS are not genetic, understanding genetic
causes may lead to more knowledge about the protein malfunction
behind the disease, Siddique said.
Location of the Chromosome area where the ALS Gene resides is a
vital step in eventually isolating the gene itself, said Dr. L.
Stern, MDA Research Dir.
The study wasbased on tissue samples from 23 families world wide
affected by the genetic form of ALS..
As you can see, we are not directly affected by this release but it
is a start and hopefully something good will come out of it for you,
Patrick , me and all other ALS Folks..
hang in.. Tony..
--
Uucp: ..!{decvax,oliveb}!bunker!hcap!hnews!382!80.0!Tony.Thoennes
Internet: Tony.Thoennes@p0.f80.n382.z1.fidonet.orgTony.Thoennes@p0.f80.n382.z1.fidonet.org (Tony Thoennes) (05/31/91)
Index Number: 15891
Just done reading a copy of the News Release and it indicates good
news but not as good as I was led to believe when I did my previous
post.. the following is excerpts from the release..
Tucson, Az, may 16, 91 - Researchers sponsored by MDA announced
today that they have located the position of the gene responsible
for one form of ALS..
The international research team reported in todays issue of the New
England Journal of Medicine that the Gene for FAMILIAL ALS is
located in a certain region of Chromosome 21, one of 46 rodlike
structures containing the human genes, the basic units of heredity.
This finding holds tremendous promise for everyone affected by ALS,
said MDA VP and Ex Dir Robert Ross..
The MDA team, headed by Dr. Teapu Siddique, used a method called
linkage analysis to find the Chromosome holding the ALS gene.
Siddique was formely at Duke Univ and now is Assoc Professor and Dir
of Research at the Dept of Neurology, Northwestern Univ Medical
School in Chicago.
This method allowed us to "Link" known genetic segments, called
markers, to a region where the gene we're seeking is located,
Siddique said. After checking more than 100 markers, the
researchers found four markers on chromosome 21 that were linked
with the ALS Gene, he said.
Although most cases of ALS are not genetic, understanding genetic
causes may lead to more knowledge about the protein malfunction
behind the disease, Siddique said.
Location of the Chromosome area where the ALS Gene resides is a
vital step in eventually isolating the gene itself, said Dr. L.
Stern, MDA Research Dir.
The study wasbased on tissue samples from 23 families world wide
affected by the genetic form of ALS..
As you can see, we are not directly affected by this release but it
is a start and hopefully something good will come out of it for you,
Patrick , me and all other ALS Folks..
hang in.. Tony..
--
Uucp: ..!{decvax,oliveb}!bunker!hcap!hnews!382!80.0!Tony.Thoennes
Internet: Tony.Thoennes@p0.f80.n382.z1.fidonet.org