KIDD%YALEMED@PUCC.PRINCETON.EDU (11/30/90)
Response to David Curtis question of 27 Nov 90 re:
"reference for calculating limits for lod scores"
The question was not phrased quite correctly, but the wording used does
highlight a common misconception. A lod score is itself a kind of significance
level (like a p value) so one doesn't usually calculate a confidence limit for
the lod score itself. One does use lod scores to determine confidence limits
for recombination frequencies. A good reference for that is:
Conneally et al. (1985) Human Gene Mapping Workshop 8 (HGM8) Cytogenetics and
Cell Genetics 40: 356-359.
G. Mapper