[bionet.population-bio] Phylogenetic correlations

T80SMS1@niu.bitnet (05/28/90)

>I've been trying to figure out the Cheverud-Dow-Leutenegger (CDL) method of
>phylogenetic autocorrelation, and am stuck.
>The equations implied by this path diagram are
>
>         r = s1 s2 rS + q1 q2 rP
>         1 = s12 + q12
>         1 = s22 + q22
>
>where r is the correlation between X1 and X2.  CDL's autocorrelation method
>gives us the values of s1 and s2, and the 2nd and 3rd equations then tell us
>q1 and q2.  This leaves 1 equation in two unknowns (rS and rP), which would
>appear to have no unique solution.  Can anyone suggest where we might find
>n additional equation that might give this system a sensible answer?

My understanding is that rP is determined from independent
information, ie. other characters are first used to determine
the phylogeny.  Thus, equation 1 has only 1 unknown and a
unique solution.

Sam Scheiner
Northern Illinois University
t80sms1@niu.bitnet

joe@GENETICS.WASHINGTON.EDU (Joe Felsenstein) (05/30/90)

In regard to Cheverud, Dow, and Leutenegger's method, I asked them when I
was shown a preprint of their work to explain how it related to other
methods such as my own contrasts method of 1985 (American Naturalist) but
have never seen it adequately explained.

One difficulty with their approach is that when two characters are
evolving in a correlated fashion this should show up in BOTH the
"phylogenetic" and "specific" components.  I believe that their method
assumes that only the latter is to be used to estimate the correlation.

If so then it must lose some power.  I think there may also be a
degrees-of-freedom problem.  If there are four species then my method
forms three contrasts and estimates regressions, correlations, etc from
those.  Theirs seems to make the estimate from four specific components,
which seems to me to be one too many.  Alan's simulations seem to show
reasonable behavior but I would be interested in seeing whether it really
does have the postulated distribution.

I would welcome being corrected on this.
-----
Joe Felsenstein, Dept. of Genetics, Univ. of Washington, Seattle, WA 98195
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