M_GINSBURG@icrf.ac.uk (03/06/91)
Does anyone know, please, of a program that will correctly identify signal sequence peptides ( not just predict the membrane spanning portion). My enquirer informs me that there are various allowed and disallowed residues besides the membrane segment which are well known/described. With thanks for your indulgence, Michelle Ginsburg. ICRF
Rainer.Fuchs%EMBL@PUCC.PRINCETON.EDU ("Rainer Fuchs ", EMBL Data Library) (03/06/91)
Michelle Ginsburg asked: > Does anyone know, please, of a program that will correctly identify > signal sequence peptides ( not just predict the membrane spanning portion). I think that almost all of the newer sequence analysis packages include options to do this. Additionally, there is a program called SIGSEQ available from the EMBL file server by A.M. Popowicz (CABIOS 4 (88), 405), incl. C source code, for DOS and UNIX. Although I haven't tried it I assume it will also run under VMS. A program called SigCleave, written by Peter Rice, is also available as part of the GCGEMBL package. Rainer Fuchs EMBL Data Library fuchs@embl-heidelberg.de fuchs@embl.bitnet