BACKD@QUCDN.QueensU.CA (02/18/91)
Archive-name: bionet/molbio/tfd/1991-02-07 Archive-directory: ncbi.nlm.nih.gov:/repository/TFD/ [130.14.20.1] Original-posting-by: BACKD@QUCDN.QueensU.CA Original-subject: Re: Eukaryotic cis-acting transcription regulatory elements Reposted-by: emv@ox.com (Edward Vielmetti) Thanks to all of those who responded to my request. This is a brief summary of my E-mail on the subject: - David Gosh (Nucl. Acids Res. 18, 1749-1756) has developed a relational database of transcription factor recognition elements called TFD. The TFD database can be obtained in one of two ways: 1. Anonymous FTP from NCBI.NLM.NIH.GOV in /repository/TFD 2. From EMBL mailer. Send a message to the mailer as follows Address: NETSERVER@EMBL.BITNET HELP HELP TFD DIR TFD The mailer will return the appropriate help files to get you started. - Dan Prestridge from Los Alamos Nat'l Labs writes that he has a program, SIGNAL SCAN available in MS-DOS or UNIX format that will scan a sequence file against the TFD database. The database is included on the disk. Mail Dan a request for either format at DXP%LIFE@LANL.GOV. The UNIX version can be E-mailed back, the MS-DOS version travels better on a diskette, so be prepared to send along two formatted discs. - Those operating in the UNIX world have a third option. MBCRR.Harvard.Edu have a UNIX program called DYNAMIC that used the TFD database directly. D. Gosh refers to the program in his NAR paper. -Be aware the TFD database is about 500K. -Good luck and thanks for all the help. Don Back, BACKD@QUCDN.QueensU.CA.BITNET (613) 545-2982