DANJ@jhuhyg.bitnet (Dan Jacobson) (04/02/91)
Archive-name: bionet/sequences/macaw/1991-04-01 Archive-directory: ncbi.nlm.nih.gov:/pub/macaw/ [130.14.20.1] Original-posting-by: DANJ@jhuhyg.bitnet (Dan Jacobson) Original-subject: PC Sequence - Summary Reposted-by: emv@msen.com (Edward Vielmetti, MSEN) Hi, There was a fare amount of traffic on my request for a program which draws boxe s around identical sites in sequence alignments and a request for a summary so here's one of the responses that didn't appaear on Bio-Soft. First of all thanks to all those that responded - the net is quite a friendly environ. There were several suggestions as seen on the bboard about dropping the alignme nt into a clipboard in windows or uploading the alignment onto a MAC and beauti fying it. The best program that I have found is called macaw. Macaw is a fancy m ultiple sequence alignment program which requires Microsoft Windows 3.0 (or hig her). Macaw is available via FTP from ncbi.nlm.nih.gov (130.14020.1) under pub/macaw. Macaw comes in a variety of compressed formats, arc, zip and lzh, - remember to import and download it using the binary mode. Macaw will only run under windows and thus your PC must have at least 1Meg of MEMORY. Macaw doesn't draw boxes but instead color codes the residues and the background in accordance with their relative similarity. On a normal printer these will come out in different shades of gray. Macaw also draws schematics of the seqences beeing compared - again can be color coded. From what I've seen so far macaw is a very nice program, many thanks go to Gre g Schuler (author) for help in getting started and Don Lehn for telling me abou t macaw in the first place. Again thanks to all who responded. Dan Jacobson danj@jhuhyg.sph.jhu.edu (internet) danj@jhuhyg (bitnet)