CZJ%NIHCU.BITNET@CUNYVM.CUNY.EDU (09/20/88)
Attached is the Table of Contents and items of interest from the
NIH Guide to Grants and Contracts ddated 9/16/88. I would
call your attention to the second item regarding the distribution of
materials and data (e.g. sequence data and crystallographic coordinates).
Jim Cassatt
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Vol. 17, No. 29, September 16, 1988
NOTICES
CLARIFICATION: REFERENCE LETTERS FOR RCDA AND FIRST GRANT
APPLICATIONS ............................................(84/94)............ 1
Division of Research Grants
Index: RESEARCH GRANTS
PHS POLICY RELATING TO DISTRIBUTION OF UNIQUE RESEARCH
RESOURCES PRODUCED WITH PHS FUNDING .....................(97/185)........... 1
National Institutes of Health
Index: NATIONAL INSTITUTES OF HEALTH
DATED ANNOUNCEMENTS
INFORMATION SYSTEMS BRANCH AUTOMATED DATA PROCESSING (ADP) (RFP) ........... 2
National Heart, Lung, and Blood Institute (191/251)
Index: HEART, LUNG, AND BLOOD
MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM ...(254/358)....... 3
Division of Research Resources
Index: RESEARCH RESOURCES
EPIDEMIOLOGIC STUDIES OF HIV-ASSOCIATED MALIGNANCIES (RFA) ...(361/454)..... 4
National Cancer Institute (2243/2554)
Index: CANCER
STUDIES OF CHRONOBIOLOGICAL EFFECTS IN CANCER TREATMENT WITH
BIOLOGICAL RESPONSE MODIFIERS AND/OR DRUGS (RFA) ......(457/584, 1204/1569). 5
National Cancer Institute
Index: CANCER
SMOKING CESSATION STRATEGIES FOR MINORITIES (RFA) .....(587/646, 1572/1997). 7
National Heart, Lung, and Blood Institute
Index: HEART, LUNG, AND BLOOD
PARTURITION: MYOMETRIAL FUNCTION AND RELATED MECHANISMS (RFA) ............. 8
National Institute of Child Health and Human Development (649/692, 2000/2240)
Index: CHILD HEALTH AND HUMAN DEVELOPMENT
CYSTIC FIBROSIS RESEARCH CENTERS (RFA) .......................(695/825)..... 8
National Institute of Diabetes and Digestive and Kidney Diseases
Index: DIABETES, DIGESTIVE AND KIDNEY DISEASES
ONGOING PROGRAM ANNOUNCEMENTS
IMMUNOGERONTOLOGY PROGRAM (PA) ...............................(831/983).....10
National Institute on Aging
Index: AGING
EFFECT OF ENVIRONMENTAL AGENTS ON THE ENDOCRINE SYSTEM (PA) ...(986/1098)...12
National Institute of Environmental Health Sciences
Index: ENVIRONMENTAL HEALTH SCIENCES
RESEARCH ON SEVERELY MENTALLY ILL PERSONS AT RISK OF OR WITH
HIV INFECTIONS (PA) ..........................................(1101/1131)...13
National Institute of Mental Health
Index: MENTAL HEALTH
NOTICES
CLARIFICATION: REFERENCE LETTERS FOR RCDA AND FIRST GRANT APPLICATIONS
P.T. 34; K.W. 0710030, 1014002
Division of Research Grants
The announcement in the March 18, 1988, issue of the NIH Guide for Grants and
Contracts (Vol. 17, No. 10) instructed applicants to use the reference forms
in the PHS 398 Kit. Only the RCDA has reference guidelines included in the PHS
398 Kit to be sent to referees. For the FIRST grant application, there are no
special reference forms or printed guidelines to be sent to referees.
PHS POLICY RELATING TO DISTRIBUTION OF UNIQUE RESEARCH RESOURCES PRODUCED WITH
PHS FUNDING
P.T. 36; K.W. 0780010
National Institutes of Health
Investigators conducting biomedical research frequently develop unique
research resources. Categories of these resources include organisms, cells,
viruses, cell products, cloned DNA, as well as DNA sequences, mapping
information and crystallographic coordinates. Some specific examples are:
specialized and/or genetically defined cells, including normal and diseased
human cells; monoclonal cell lines; hybridoma cell lines; microbial cells and
products; viruses and viral products; recombinant nucleic acid molecules; DNA
probes; nucleic acid and protein sequences; and transgenic mice. The Public
Health Service (PHS) provides the following statement of policy concerning
unique research resources developed through its awards.
A. PHS Policy on Distribution of Research Resources.
It is the policy of the PHS to make available to the public the results and
accomplishments of the activities that it funds. Restricted availability of
unique resources upon which further studies are dependent can impede the
advancement of research and the delivery of medical care. Therefore, when
these resources are developed with PHS funds and the associated research
findings have been published or after they have been provided to NIH under
contract, they should be made readily available for research purposes to the
scientific community. This policy applies to NIH intramural research as well
as extramural research funded by grants, and cooperative agreements, and
contracts.
Investigators who have such resources are encouraged to consult the
appropriate PHS Program Administrators who may be of assistance in determining
a suitable distribution mechanism. For research and development contracts,
approval should be obtained from the NIH Contracting Officer before
distribution of unique resources, unless the terms of the contract permit
distribution without prior clearance of the Contracting Officer. In order to
facilitate the availability of unique or novel biological materials and
resources developed with PHS funds, investigators may distribute the materials
through their own laboratory or institution or submit them, if appropriate, to
entities such as the American Type Culture Collection or similar repositories.
In the case of unique biological information such as DNA sequences or
crystallographic coordinates, investigators are expected to submit them to the
appropriate data banks because they otherwise are not truly accessible to the
scientific community. When distributing unique resources, investigators are
encouraged to include pertinent information on the nature, or quality, or
characterization of the materials.
Investigators must exercise great care to ensure that
resources do not identify original donors or subjects, directly or through
identifiers, such as codes linked to the donors or subjects.
B. Distribution Costs
Institutions and investigators may charge the requester, if necessary, for the
reasonable cost of production of unique biological materials, and for
packaging and shipping. Such costs may include personnel, supplies, and other
directly related expenses. It should be noted, however, that such a charge
accrues as general program income. This should not be an impediment to the
distribution of materials, but investigators and institutions are advised
that:
Vol. 17, No. 19, September 16, 1988 - Page 1
a) for grants, the income is governed by 45 CFR Part 74 and it must be
reported on the Financial Status Report. Questions regarding these policies
and the treatment of income should be directed to the Grants Management
Officer.
b) for contracts, the income is governed by Federal Acquisition Regulations
(FAR) 45.610-3. Contracting Officers must be contacted before generating any
revenues from the distribution of materials. Any contract under which
research resources would be sold require specific contract instructions.
Existing contracts may require an amendment and specific approval of the
Contracting Officer to render them allowable.
C. Inventions and Commercialization
This policy does not discourage, impede or prohibit the organization that
develops unique biologic materials or intellectual property from
commercializing the materials or licensing them for commercial purposes.
Investigators may make their materials available to others with appropriate
restrictions and licensing terms as they and their institutions deem
necessary.
Institutions are reminded that some of these products may be inventions
subject to the various laws and regulations applicable to patents and need to
be reported. When reporting is required, it should occur at the earliest
possible time. (See P.L. 96-517 P.L. 98-620 and 37 CFR 40l)
DATED ANNOUNCEMENTS (RFPs AND RFAs)
INFORMATION SYSTEMS BRANCH AUTOMATED DATA PROCESSING (ADP)
RFP AVAILABLE: NHLBI-HO-88-08
P.T. 18, 38; K.W. 1004017
National Heart, Lung, and Blood Institute
The overall objective of this contract is to analyze, design, implement,
document, maintain, and program seven mainframe and microcomputer applications
and systems over a five-year period. These seven systems are: 1) Tracking
and Budget System (TABS); 2) Contracts Tracking and Budget System (CTABS); 3)
TABS Microcomputer Budget System; 4) Trans-National Institute of Health (NIH),
Basic/Applied/ Developmental, and Private Sector Microcomputer System; 5)
Council Microcomputer System; 6) National Program Microcomputer System, and 7)
Computer Retrieval of Information and Scientific Projects (CRISP)
Microcomputer System.
Proposals must clearly present plans detailing the technical approaches,
procedures, and time schedules for completing the five performances stages for
each of the seven projects. These performance stages are: 1) Analysis; 2)
Evaluation; 3) Design/Specification; 4) Programming; and 5) Testing/
Implementation. New systems and/or modifications to existing systems shall be
thoroughly tested and documented before implementation, and system users are
to be trained by the contractor.
Offerors will be asked to present plans for training staff in the use of the
seven computer projects. Design and implementation of microcomputer systems
must also address the fact that systems implemented on individual
microcomputers will be moved to Local Area Networks (LANs) as they become
operational.
It is anticipated that four full-time equivalents with the following expertise
will be required for the successful completion of the study: 1) a senior
programmer/analyst with managerial skills to serve as project manager; 2) a
senior programmer/analyst; and 3) two programmers.
This announcement is not a request for proposal (RFP). It is anticipated that
RFP-NHLBI-HO-88-08 will be available on or about September 1, 1988, with
proposals due on November 1, 1988. To receive a copy of the RFP, please
supply this office with three (3) self-addressed mailing labels. The RFP
package will be available upon written request to:
Vol. 17, No. 29, September 16, 1988
Joanne C. Paolucci
Contract Specialist for
Division of Lung Diseases
Contracts Operations Branch
Westwood Building, Room 654
Bethesda, Maryland 20892
This proposed program is totally 100 percent set aside for small business
competition. Only responsible small business firms as defined pursuant to
Part 19 of the Federal Acquisition Regulation are asked to respond to this
synopsis. The Standard Industrial Classification Number is 7379.
MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM
P.T. 34, 44, FF; K.W. 0720005
Division of Research Resources
Application Receipt Date: December 1, 1988
BACKGROUND AND OBJECTIVES
The Division of Research Resources (DRR), National Institutes of Health (NIH)
currently plans to continue the Minority High School Student Research
Apprentice Program in 1989.
The purpose of the program is to provide minority high school students with a
meaningful experience in various aspects of health-related research in order
to stimulate their interest in careers in science.
ELIGIBILITY
Eligible institutions are those that were awarded grants during the latest
complete Federal fiscal year 1988 from either the Biomedical Research Support
Grant (BRSG) Program or the Minority Biomedical Research Support (MBRS)
Program, both of which are administered by DRR, NIH. Only one application for
the Apprentice Program can be submitted by a component of an institution that
is the recipient of both the BRSG and MBRS awards.
Students eligible for support under this program are those who: (1) identify
themselves as minority (i.e., Black, Hispanic, American Indian, Alaskan
Native, Pacific Islander, or Asian); (2) are U.S. citizens or have a permanent
visa; and (3) are enrolled in high school during the 1988-89 academic year.
(Students who will graduate from high school in 1989 are eligible, as is a
student who participated in a previous year - provided he/she is still
enrolled at the high school level.)
MECHANISM OF SUPPORT
The mechanism of support for this program will be the NIH grant-in-aid.
Support will be provided at a level of $1,500 for each apprentice position
allocated. No indirect costs will be paid. Direct support to the apprentice
must be as salary; stipends are not allowed. Within the $1,500 per student
allocation, funds may also be utilized for supplies, extending the research
experience, or if adequate funds exist, for the addition of an apprentice.
However, funds from these grants may only be used for the costs of the
apprentice program. The Program Director is responsible for recruitment and
selection of the apprentices and assignment of each to an investigator.
Recruitment and selection of students should emphasize factors of the
students' motivation, ability and scholastic aptitude and accomplishments. In
addition, consideration should be given to science teachers' recommendations
and where possible the degree of parental commitment. Assignments should be
made to investigators involved in health-related research who are committed to
developing in the high school students both understanding of the research in
which they participate and the technical skills needed.
APPLICATION
Eligible institutions should submit an application consisting of no more than:
1. A one-page letter stating the number of student positions requested, plus
2. An original and two signed and completed copies of the Grant Application
Form, PHS 398 (Rev. 09/86) face page only.
Mark the "YES" box in item 2 and indicate the announcement title as "Minority
High School Student Research Apprentice Program."
Vol. 17, No. 29, September 16, 1988 - Page 3
Mark items numbered 4, 5, 7, 8b, 10 and 14 Not applicable (N.A.). Complete
item 8a with the total dollar amount of your request, which is the sum of the
number of student positions requested times $1,500 per student.
The original and one copy of the signed Program Director's report and each
student report should be submitted with the renewal application due December 1
annually in order that the data contained in these reports can be used by DRR
to decide about policies and future funding for the Minority High School
Student Research Apprentice Program. These reports should also be submitted
at the same time even if renewal support is not requested.
In any event, all reports including the Financial Status Report must be
submitted to the NIH by the grantee institution no later than May 31, 1989
unless an extension of the budget period end date has been authorized.
Please Note: Limited funds and increased requests for such student positions
may restrict the final allocations by DRR to three or four students per
eligible applicant institution. Upon recommendation of the National Advisory
Research Resources Council, the Division will give preference in making awards
to those institutions that can support a summer program having a "critical
mass" of at least five or six students using institutional as well as DRR
funds.
The applications should be submitted to:
Biomedical Research Support Program
Division of Research Resources
National Institutes of Health
Building 31, Room 5B-23
9000 Rockville Pike
Bethesda, Maryland 20892
Inquiries can be made of Dr. Marjorie A. Tingle at the above indicated address
or by calling (301) 496-6743.
The firm deadline for receipt of applications is December 1, 1988. Awards
will be effective March 1, 1989, contingent upon availability of appropriated
funds.