[bionet.sci-resources] NIH Guide, vol. 19, no. 37, 12 October 1990

kristoff@GENBANK.BIO.NET (Dave Kristofferson) (10/12/90)

NIH GUIDE - Vol. 19, No. 37, October 12, 1990


                                   NOTICES


AAMC/NIH REGIONAL WORKSHOPS ..........................(84/120)............... 1
National Institutes of Health
Index:  NATIONAL INSTITUTES OF HEALTH


AVAILABILITY OF REVISED KEYWORD THESAURUS (4TH EDITION) ..(123/147).......... 1
National Institutes of Health
Index:  NATIONAL INSTITUTES OF HEALTH


                   NOTICES OF AVAILABILITY (RFPs AND RFAs)


MASTER AGREEMENT FOR CEREBROVASCULAR CLINICAL RESEARCH (RFP) ..(164/252)..... 2
National Institute of Neurological Disorders and Stroke
Index:  NEUROLOGICAL DISORDERS, STROKE


CORTICAL CONTROL OF NEURAL PROSTHETIC DEVICES (RFP) ...........(255/298)..... 3
National Institute of Neurological Disorders and Stroke
Index:  NEUROLOGICAL DISORDERS, STROKE


                                   NOTICES


AAMC/NIH REGIONAL WORKSHOPS

P.T. 42; K.W. 1014004

National Institutes of Health

On November 16-17, the University of California, San Diego will host the
second of four regional workshops sponsored by the Association of American
Medical Colleges (AAMC), under contract with the National Institutes of Health
(NIH), to address issues in the promotion of integrity and responsibility in
biomedical research.  These regional workshops are designed to serve as a
forum for discussing recent developments within the Public Health Service that
include the establishment of the Office of Scientific Integrity and the new
regulation requiring awardee institutions to assure that policies and
procedures are in place for investigating possible misconduct in science.  The
workshop will address special topics such as normal and deviant behavior in
the laboratory; handling allegations of misconduct; techniques for teaching
ethics; publication practices; and data ownership and access as well as
dissemination of the information developed by the Institute of Medicine study,
"Promotion of Responsibility in Research in the Health Sciences," supported by
the NIH.  The workshop is expected to be of interest to program directors,
investigators, and academic administrators involved in behavioral and
biomedical research.  CME credits will be available for the workshop through
the University of Calfornia, San Diego Office of Continuing Medical Education.

Title:  Biomedical Research Integrity in the 90's:  New Approaches and New
Regulations

Location:  Hyatt Regency La Jolla, San Diego, California

Contact:

Office of Continuing Medical Education
University of California, San Diego
M-017
La Jolla, CA  92093-0617
Telephone:  (619)  534-3940


AVAILABILITY OF REVISED KEYWORD THESAURUS (4th Edition)

P.T. 34; K.W. 1014000

National Institutes of Health

The Keyword Thesaurus that is used to classify NIH Guide notices,
announcements, RFAs and RFPs was revised in September 1990.  Participating
agencies are the National Science Foundation, National Institutes of Health,
Department of Energy, Office of Naval Research, and National Aeronautics and
Space Administration.

An objective of the standardized classification scheme is to make it possible
to use the same keyword terms across various Federal agencies that agree to
participate.  For more information about the revised edition, or to order a
copy for your organization, contact:

Rodman & Associates
Infomart
1950 Stemmons Freeway
Dallas TX  75207
Telephone:  (214) 746-5345

Later this fall, the Biomedical and Medical Sciences section of the Thesaurus
will be published in an issue of the NIH Guide for Grants and Contracts.


            NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 1
                   NOTICES OF AVAILABILITY (RFPs AND RFAs)


MASTER AGREEMENT FOR CEREBROVASCULAR CLINICAL RESEARCH

MAA/RFP AVAILABLE:  NIH-NINDS-90-16

P.T.

National Institute of Neurological Disorders and Stroke

The National Institute of Neurological Disorders and Stroke (NINDS) is seeking
proposals with the intent of awarding Master Agreements (MAs) to sources
capable of performing clinical evaluations of new investigational forms of
therapies and intervention efforts aimed at preventing and (or) treating
cerebrovascular diseases in an attempt at reducing disability, optimizing
functional recovery, and improving the quality of life.  Offerors may qualify
under any number of the 6 specific project categories listed below.  It is
possible for an organization to qualify under all 6 categories.  Recipients of
MA awards may compete for award under future "quick reaction" MA Order/RFPs
for studies in the category(ies) for which they receive an MA award.  Current
MA holders will not be required to compete and requalify unless they wish to
be considered for award under a category for which they have not already
qualified.

Category I - Clinical Research Studies on Transient Ischemic Attack (TIA);

Category II - Clinical Research Studies of Acute Ischemic Stroke;

Category III - Clinical Research Studies of Generalized Cerebral Ischemia;

Category IV - Clinical Research Studies on Intracranial Aneurysms and
Subarachnoid Hemorrhage;

Category V - Cinical Research Studies on Intracerebral Hemorrhage;

Category VI - Clinical Research Studies on Dementia Secondary to
Cerebrovascular Disease.

An MA is an agreement issued to sources who qualify under MAA/RFP
solicitations to compete for future tasks issued under the general study areas
described in an MA.  These agreements contain general terms, conditions, and
parameters of performance for the particular study category(ies) that the MA
holder is judged capable of competing for and performing.  Award of an MA
under the MAA/RFP will certify that an offeror has demonstrated that it has
the staff expertise, capability, facilities, and access to an adequate study
population to compete for future MA Order task requirements issued under the
Cerebrovascular Clinical Research project.  The agreements will not contain
specific work tasks nor any funding commitments.

Competition of future MAO tasks will be restricted to qualified MA holders,
and successful MA competitors may receive an MAO award.  An MAO is a bilateral
contract and an operational addendum to an MA.  The MAO outlines the specific
performance requirements, including a detailed Statement of Work and Delivery
Schedule, and indicates the negotiated funding commitment for the particular
study task.

It is anticipated that as a result of this solicitation, multiple MA awards
will be made.  MA awards resulting from this RFP will be vaild through May 31,
1994.  It is important that offerors review carefully the 6 individual
category descriptions and requirements and the evaluation criteria contained
in the MAA/RFP prior to attempting a response to the solicitation.  Offerors
must provide concise information regarding their capability to accrue the
required number of specific subjects indicated in the MAA/RFP.

This is an announcement of an anticipated MAA/RFP.  The MAA/RFP will be issued
on or about October 11, 1990, with the closing date for receipt of proposals
set approximately for December 18, 1990.  All responsible sources may submit a
proposal which will be considered by the Agency.  Copies of the MAA/RFP may be


            NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 2
obtained by sending a written request and two self-addressed mailing labels
to:

Deloris Selleh
Contract Specialist
Contracts Management Branch
National Institute of Neurological Disorders and Stroke, NIH
Federal Building, Room 901
7550 Wisconsin Avenue
Bethesda, MD  20892

Attention:  MAA/RFP No. NIH-NINDS-90-16


CORTICAL CONTROL OF NEURAL PROSTHETIC DEVICES

RFP AVAILABLE:  NIH-NINDS-90-17

P.T.

National Institute of Neurological Disorders and Stroke

The Neural Prosthesis Program of the National Institute of Neurological
Disorders and Stroke, NIH, is committed to research and development to provide
functional neuromuscular stimulation (FNS) to restore hand and arm function in
quadriplegic individuals at the highest functional level possible.  These FNS
systems must operate under the voluntary control of the individual.  Providing
a means for the individual to produce the control signals represents a
critical part of any potential FNS system.  Presently, control signals are
generated by voluntary movements of unparalyzed muscles such as the
contralateral shoulder or through voice-activated control.  The goal of the
proposed project will be to establish the feasibility of generating control
signals through voluntary control of neurons in the central nervous system
(CNS).  To demonstrate functional cortical control it is necessary to show
that selected cell populations in the CNS can be trained to reliably control
an electromechanical device.  This must first be demonstrated in an intact
animal, and, if successful, then also demonstrated in the spinal lesioned
adult animal.  The Contractor will be required to exert its best efforts to
demonstrate in a non-human primate the feasibility of generating control
signals from CNS neural activity and will determine the factors that
contribute to a reliable neural control channel.  It is anticipated that one
award will be made for a period of five years on or about May 1, 1991.

This is not a Request for Proposals (RFP).  RFP No. NIH-NINDS-90-17 will be
available on October 15, 1990.  Responses will be due by December 17, 1990.

To receive a copy of the RFP, please submit a written request to the following
address, and supply this office with two self-addressed mailing labels.  All
responsible sources shall be considered by the agency.

Contracting Officer
Contracts Management Branch, DEA
National Institute of Neurological Disorders and Stroke, NIH
Federal Building, Room 901
7550 Wisconsin Avenue
Bethesda, MD  20892

Attention:  RFP No. NIH-NINDS-90-17


            NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 3