kristoff@GENBANK.BIO.NET (Dave Kristofferson) (10/12/90)
NIH GUIDE - Vol. 19, No. 37, October 12, 1990 NOTICES AAMC/NIH REGIONAL WORKSHOPS ..........................(84/120)............... 1 National Institutes of Health Index: NATIONAL INSTITUTES OF HEALTH AVAILABILITY OF REVISED KEYWORD THESAURUS (4TH EDITION) ..(123/147).......... 1 National Institutes of Health Index: NATIONAL INSTITUTES OF HEALTH NOTICES OF AVAILABILITY (RFPs AND RFAs) MASTER AGREEMENT FOR CEREBROVASCULAR CLINICAL RESEARCH (RFP) ..(164/252)..... 2 National Institute of Neurological Disorders and Stroke Index: NEUROLOGICAL DISORDERS, STROKE CORTICAL CONTROL OF NEURAL PROSTHETIC DEVICES (RFP) ...........(255/298)..... 3 National Institute of Neurological Disorders and Stroke Index: NEUROLOGICAL DISORDERS, STROKE NOTICES AAMC/NIH REGIONAL WORKSHOPS P.T. 42; K.W. 1014004 National Institutes of Health On November 16-17, the University of California, San Diego will host the second of four regional workshops sponsored by the Association of American Medical Colleges (AAMC), under contract with the National Institutes of Health (NIH), to address issues in the promotion of integrity and responsibility in biomedical research. These regional workshops are designed to serve as a forum for discussing recent developments within the Public Health Service that include the establishment of the Office of Scientific Integrity and the new regulation requiring awardee institutions to assure that policies and procedures are in place for investigating possible misconduct in science. The workshop will address special topics such as normal and deviant behavior in the laboratory; handling allegations of misconduct; techniques for teaching ethics; publication practices; and data ownership and access as well as dissemination of the information developed by the Institute of Medicine study, "Promotion of Responsibility in Research in the Health Sciences," supported by the NIH. The workshop is expected to be of interest to program directors, investigators, and academic administrators involved in behavioral and biomedical research. CME credits will be available for the workshop through the University of Calfornia, San Diego Office of Continuing Medical Education. Title: Biomedical Research Integrity in the 90's: New Approaches and New Regulations Location: Hyatt Regency La Jolla, San Diego, California Contact: Office of Continuing Medical Education University of California, San Diego M-017 La Jolla, CA 92093-0617 Telephone: (619) 534-3940 AVAILABILITY OF REVISED KEYWORD THESAURUS (4th Edition) P.T. 34; K.W. 1014000 National Institutes of Health The Keyword Thesaurus that is used to classify NIH Guide notices, announcements, RFAs and RFPs was revised in September 1990. Participating agencies are the National Science Foundation, National Institutes of Health, Department of Energy, Office of Naval Research, and National Aeronautics and Space Administration. An objective of the standardized classification scheme is to make it possible to use the same keyword terms across various Federal agencies that agree to participate. For more information about the revised edition, or to order a copy for your organization, contact: Rodman & Associates Infomart 1950 Stemmons Freeway Dallas TX 75207 Telephone: (214) 746-5345 Later this fall, the Biomedical and Medical Sciences section of the Thesaurus will be published in an issue of the NIH Guide for Grants and Contracts. NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 1 NOTICES OF AVAILABILITY (RFPs AND RFAs) MASTER AGREEMENT FOR CEREBROVASCULAR CLINICAL RESEARCH MAA/RFP AVAILABLE: NIH-NINDS-90-16 P.T. National Institute of Neurological Disorders and Stroke The National Institute of Neurological Disorders and Stroke (NINDS) is seeking proposals with the intent of awarding Master Agreements (MAs) to sources capable of performing clinical evaluations of new investigational forms of therapies and intervention efforts aimed at preventing and (or) treating cerebrovascular diseases in an attempt at reducing disability, optimizing functional recovery, and improving the quality of life. Offerors may qualify under any number of the 6 specific project categories listed below. It is possible for an organization to qualify under all 6 categories. Recipients of MA awards may compete for award under future "quick reaction" MA Order/RFPs for studies in the category(ies) for which they receive an MA award. Current MA holders will not be required to compete and requalify unless they wish to be considered for award under a category for which they have not already qualified. Category I - Clinical Research Studies on Transient Ischemic Attack (TIA); Category II - Clinical Research Studies of Acute Ischemic Stroke; Category III - Clinical Research Studies of Generalized Cerebral Ischemia; Category IV - Clinical Research Studies on Intracranial Aneurysms and Subarachnoid Hemorrhage; Category V - Cinical Research Studies on Intracerebral Hemorrhage; Category VI - Clinical Research Studies on Dementia Secondary to Cerebrovascular Disease. An MA is an agreement issued to sources who qualify under MAA/RFP solicitations to compete for future tasks issued under the general study areas described in an MA. These agreements contain general terms, conditions, and parameters of performance for the particular study category(ies) that the MA holder is judged capable of competing for and performing. Award of an MA under the MAA/RFP will certify that an offeror has demonstrated that it has the staff expertise, capability, facilities, and access to an adequate study population to compete for future MA Order task requirements issued under the Cerebrovascular Clinical Research project. The agreements will not contain specific work tasks nor any funding commitments. Competition of future MAO tasks will be restricted to qualified MA holders, and successful MA competitors may receive an MAO award. An MAO is a bilateral contract and an operational addendum to an MA. The MAO outlines the specific performance requirements, including a detailed Statement of Work and Delivery Schedule, and indicates the negotiated funding commitment for the particular study task. It is anticipated that as a result of this solicitation, multiple MA awards will be made. MA awards resulting from this RFP will be vaild through May 31, 1994. It is important that offerors review carefully the 6 individual category descriptions and requirements and the evaluation criteria contained in the MAA/RFP prior to attempting a response to the solicitation. Offerors must provide concise information regarding their capability to accrue the required number of specific subjects indicated in the MAA/RFP. This is an announcement of an anticipated MAA/RFP. The MAA/RFP will be issued on or about October 11, 1990, with the closing date for receipt of proposals set approximately for December 18, 1990. All responsible sources may submit a proposal which will be considered by the Agency. Copies of the MAA/RFP may be NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 2 obtained by sending a written request and two self-addressed mailing labels to: Deloris Selleh Contract Specialist Contracts Management Branch National Institute of Neurological Disorders and Stroke, NIH Federal Building, Room 901 7550 Wisconsin Avenue Bethesda, MD 20892 Attention: MAA/RFP No. NIH-NINDS-90-16 CORTICAL CONTROL OF NEURAL PROSTHETIC DEVICES RFP AVAILABLE: NIH-NINDS-90-17 P.T. National Institute of Neurological Disorders and Stroke The Neural Prosthesis Program of the National Institute of Neurological Disorders and Stroke, NIH, is committed to research and development to provide functional neuromuscular stimulation (FNS) to restore hand and arm function in quadriplegic individuals at the highest functional level possible. These FNS systems must operate under the voluntary control of the individual. Providing a means for the individual to produce the control signals represents a critical part of any potential FNS system. Presently, control signals are generated by voluntary movements of unparalyzed muscles such as the contralateral shoulder or through voice-activated control. The goal of the proposed project will be to establish the feasibility of generating control signals through voluntary control of neurons in the central nervous system (CNS). To demonstrate functional cortical control it is necessary to show that selected cell populations in the CNS can be trained to reliably control an electromechanical device. This must first be demonstrated in an intact animal, and, if successful, then also demonstrated in the spinal lesioned adult animal. The Contractor will be required to exert its best efforts to demonstrate in a non-human primate the feasibility of generating control signals from CNS neural activity and will determine the factors that contribute to a reliable neural control channel. It is anticipated that one award will be made for a period of five years on or about May 1, 1991. This is not a Request for Proposals (RFP). RFP No. NIH-NINDS-90-17 will be available on October 15, 1990. Responses will be due by December 17, 1990. To receive a copy of the RFP, please submit a written request to the following address, and supply this office with two self-addressed mailing labels. All responsible sources shall be considered by the agency. Contracting Officer Contracts Management Branch, DEA National Institute of Neurological Disorders and Stroke, NIH Federal Building, Room 901 7550 Wisconsin Avenue Bethesda, MD 20892 Attention: RFP No. NIH-NINDS-90-17 NIH GUIDE - Vol. 19, No. 37, October 12, 1990 - Page 3