[bionet.molbio.evolution] DNA hybridization wars

GOAD.DAVISON@BIONET-20.BIO.NET (Dan Davison) (10/09/88)

The 23 September and 30 September issues of Science have a two-part
article on the current controversy over the "DNA clock" results
of Sibley and Ahlquist vs. Sarich et al.

In brief, there is some concern that the data analysis methods used
by Sibley and Ahlquist biased their results.  This is particularly
important because their hybridization results have placed humans
and chimps closer together than either is to the gorilla.  This
is in distinct contrast to most other (perhaps *all* other) 
phylogenetics comparisons of the three species.

The article is recommended on several levels: the sociology of
science, the analysis of hybridization data, and the peer review
process.

Personally, I do not believe that hybridization data such as these
are usable for analysis of close phylogenetic relationships.  The
presence of fractured, highly repetitive elements is one good reason,
among several others.

dan davison
theoretical biology / los alamos national lab / t-10 ms k710
los alamos, nm 87545 / dd@lanl.gov / ...cmcl2!lanl!dd
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