[bionet.molbio.evolution] Reminder about the AIDS Database

SYEH@BIONET-20.BIO.NET (Spencer Yeh) (07/13/89)

It has come to my attention that some AIDS researchers are unaware of
the extremely useful AIDS database produced by Los Alamos National
Laboratory under the direction of Gerald Myers.  The database is
available on-line on BIONET in IntelliGenetics format, and directly
from LANL in diskette form.  Below I'm appending some general
information about this database:

@help aids

                LANL Human Retroviruses and AIDS 1989
                           Dated April 1989

The AIDS database is maintained and produced by the Theoretical
Division of the Los Alamos National Laboratory under funding by the
Acquired Immunodeficiency Syndrome Program of the National Institute
of Allergy and Infectious Diseases.  In its original form, the
database consists of both a written manual consisting of the printed
form of HIV and SIV nucleic acid sequences, amino acid sequences, and
related nucleic acid sequences, analysis of the sequences including
alignments and phylogeny trees, as well as a diskette version of the
sequences for computer analysis.  It is suggested that researchers in
this field obtain the original form of the database in order to
acquire the extensive manual which is not available with the BIONET
version.  The original database is available at no cost to any
interested investigator.  Please see the subtopic "Contact Address"
below.  Although the nucleic acid sequences distributed in the AIDS
database are also submitted to GenBank, the sequences often appear
sooner in the AIDS database.

The original sequence data files are distributed by LANL in GenBank
form for nucleic acid sequences and in the older PIR floppy disk form
for protein sequences.  Alternatively, a subscriber may obtain the
same database in EMBL format.  The database is currently available in
MS-DOS format, and the MacIntosh version should be available shortly.

These files have been converted to IntelliGenetics format by the
BIONET staff in order that users may utilize the database in
conjuction with the programs on BIONET.  All of the AIDS files are
located in the AIDS: directory with either the extension ".seq" for
nucleic acid sequence files or ".pep" for amino acid sequence
translations of the open reading frames.

NOTE:  Some of the "sibling" HIV and SIV sequences are no longer
distributed by LANL.  Please read the release notes for details.

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Subtopics:  Release Notes
            Using the AIDS database on BIONET
            Entry Name Conventions
            Data Submission
            Contact Address
	    
or press the return key to return the @ prompt.  Entering HELP DATABASES
after the @ prompt returns to the DATABASES menu and HELP ME after the
@ prompt returns to the main menu.

Choose a subtopic (? for help): contact

For additions, corrections, or suggestions for the AIDS database please
contact Gerald Myers at the following address:

    Gerald Myers
    Theoretical Division
    T-10, Mail Stop K710
    Los Alamos National Laboratory
    Los Alamos, NM  87545

    Telephone:        (505) 665-0480
    E-mail address:   glm@lanl.gov

The original diskette and hardcopy form of the database may be
obtained free of charge by sending a request to Kersti MacInnes at the
same address.



 
Sincerely,

Spencer Yeh			Internet: bionet@bionet-20.bio.net
Applications Analyst			      (for BIONET issues) 
BIONET					 

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