[bionet.molbio.evolution] multiple alignment software

DHIGGINS@vax1.tcd.ie (Des Higgins) (07/27/89)

CLUSTAL: multiple DNA or protein sequence alignment software.


I am distributing a program for performing multiple sequence
alignments.  This is a VAX/VMS Fortran version of a package
that I normally distribute on floppy disk for PC's.  The program
can handle up to 100 sequences of max. length 5000 residues.  In
cases where the sequences to be aligned are reasonably similar, the
results are excellent and very difficult to improve by eye.  Also,
the alignments are very fast for short sequences (say 500 residues
or less).

To get the VAX version, send me a mail message at the e-mail adress
below and I will send it to you.  If you have difficulties mailing
me, give me a call and I may be able to mail you.  If you want the
PC version, send me 1 high density (1.2 mb.) 5.25 inch, formatted
diskette or 3 low density (360 kb.) diskettes.


Des Higgins  Genetics Department, Trinity College, Dublin 2, Ireland.
 dHiggins@vax1.tcd.ie
 (irl.) 1-772941 ext. 1969

Higgins, D.G. and Sharp, P.M. (1988)
   Clustal: a package for performing multiple sequence alignment on a
   microcomputer.  Gene, vol. 73, pp. 237-244.

Higgins, D.G. and Sharp, P.M. (1989)
   Fast and sensitive multiple sequence alignments on a microcomputer.
   CABIOS, vol. 5, pp. 151-153.