BIORELAY@BIO.CAM.AC.UK (02/19/88)
From: BIORELAY@BIO.CAM.AC.UK SEQNET - CHANGE OF ADDRESS Please mail bulletins for inclusion in SEQNET to: SEQNET@UK.AC.CAM.BIO which is the Cambridge University Molecular Biology VAX 8350. Please do not use the old address: SEQNET@UK.AC.CAM.PHX nor MJB1@UK.AC.CAM.VMS-SUPP Also, note that the BIORELAY@UK.AC.CAM.BIO should not be used for messages as it will only receive error reports. Thank you. Martin Bishop. 18 Feb 1988.
BIORELAY@BIO.CAM.AC.UK (02/20/88)
From: BIORELAY@BIO.CAM.AC.UK From: Georges Ware <Ware@UK.AC.AUCC> 19-FEB-1988 14:13 To: SEQNET Subj: Re: SEQNET Date: Fri, 19 Feb 88 14:11 GMT A NEW INTERNATIONAL ELECTRONIC JOURNAL IN THE UK ------------------------------------------------ A new Bulletin Board, in the form of an electronic journal, has been set up on the Bristol University Mainframe. The Journal is open to receive communications on any scientific subject, but particularly on Molecular Microbiology. Publication in the Journal is FREE. Papers submitted will be published IMMEDIATELY they are received. Papers will NOT be refereed nor Edited before publication. The Journal should, therefore, prove a rapid and expanding site for dissemination of information prior to publication through normal channels. Papers already accepted for publication elsewhere but not yet published are welcome. This Bulletin Board is not a 'chat-show' and contributions can not be made directly by authors. Contributions, which should be more or less in 'journal format', should be sent EITHER by electronic mail to: BRUNEP at UK.AC.BRISTOL OR, by post, as a plain-ASCII text file on IBM-compatible 360Kb 5.25-inch floppy disc, to: The Editor, BRUNEP, The Department of Microbiology, The University of Bristol, BS8 1TD. U.K. (Telephone 272-303500) Contributions in any other form will NOT be accepted. Papers should preferably be in English, but papers in other European languages may be submitted. The Journal can be read by anyone simply by entering the Bristol Mainframe. The Computer is connected to the academic network JANET which can be reached from PSS using the gateway address 23421920014869 Once connected to JANET the address UK.AC.BRISTOL.MULTICS is adequate. For those needing an absolute address, 00006021000100 should be used, prefixed by a full-stop i.e. .00006021000100 Telephone 'modem' connection is also possible: 272-215401 (300 baud offers direct connection to Multics) On connection to Multics the following 'banner' will be received. --------------------------------------------------------------------------- Multics MR22.0: Avon Universities, Bristol (Channel c.h008) Load = 38.4 out of 160.0 units: users = 34, 01/06/88 1345.6 gmt Wed --------------------------------------------------------------------------- Users should then type enter BRUNEP (the abreviation 'e BRUNEP' may also be used) No prior registration is necessary, and USE OF THE JOURNAL IS FREE and SELF-EXPLANATORY. PAPERS ARE URGENTLY NEEDED TO GET THE JOURNALS GOING! FURTHER DEATILS CAN BE OBTAINED BY ENTERING THE JOURNAL.
BIORELAY@BIO.CAM.AC.UK (02/24/88)
From: BIORELAY@BIO.CAM.AC.UK More European Molecular Biologists. On VAX/VMS you can @ the file to unpick it. Please send your details if you have not already done so. $WRITE SYS$OUTPUT "Creating DOELZ." $CREATE DOELZ. $DECK From: doelz@ch.unibas.urz Dr. Reinhard Doelz Biophysics Department - Biocomputing BIOZENTRUM Klingelbergstr. 70 CH-4056 BASEL $EOD $WRITE SYS$OUTPUT "Creating HOLMES." $CREATE HOLMES. $DECK NAME: EDDIE HOLMES ADDRESS: DEPT. OF ZOOLOGY, UNIVERSITY OF CAMBRIDGE, DOWNING STREET, CAMBRIDGE, CB2 3EJ. COUNTRY: UK PHONE: 0223-336650 NETWORK ID: EH102@UK.AC.CAM.PHX PROFESSION: LOWLY RESEARCH STUDENT RESEARCH MOLECULAR EVOLUTION, MAMMALIAN EVOLUTION, PROBABILISTIC INTERESTS: MODELLING, CLASSIFICATION, PROSIMIANS. $EOD $WRITE SYS$OUTPUT "Creating MURRAYRUST." $CREATE MURRAYRUST. $DECK Peter Murray-Rust Glaxo Group Research Greenford Road MIDDX UB6 0HE PMR1716@UK.CO.GLAXO You might well encounter some problems mailing to this address: - We are commercial and there might be political problems (I hope not) - Part of the transmission has to involve PSS (I think BT insist) and this probably means someone has to pay - Our X25 is problematical at present! I am however very keen on developing an electronic Club for UK macromolecualr sc s to the Protein Engineering Club. IWe are also hoping to mount our software at daresbury soon (as well as distribu ting it more widely) and hope that that might become some sort of focus. Do you run any sort of interactive bulletin board at Cambridge or is it all by mail to identified recipients? For this year (1988) I am seconded to York and it is probably safer to mail me PMR@UK.AC.YORK.YORVIC Any comments would be welcome. Peter Murray-Rust $EOD $WRITE SYS$OUTPUT "Creating PARTIS." $CREATE PARTIS. $DECK NAME: Dr Mick Partis ADDRESS: Biochemistry & Molecular Biology, Institute of Horticultural Research, Worthing Road CITY: Littlehampton COUNTY: W. Sussex. BN17 6LP. COUNTRY: U.K. PHONE: 0903-716123 TELEX: ! TELEFAX: 0903-726780 NETWORK PARTIS @UK.AC.AFRC.GCRI PROFESSION: Biochemist INTERESTS: Protein & Nucleic acid Sequence Analysis. Plant Molecular Biology. GENERAL: This address can be used to contact my colleagues Dr B. Thomas and Dr B. Jordan. $EOD $WRITE SYS$OUTPUT "Creating SACCONE." $CREATE SACCONE. $DECK NAME: CECILIA SACCONE ADDRESS: DIPARTIMENTO DI BIOCHIMICA E BIOLOGIA MOLECOLARE UNIVERSITA' DI BARI, VIA AMENDOLA 165/A 70126 BARI (ITALY) CITY: BARI COUNTRY: ITALY PHONE: (080)243303 TELEX: 810333 PHISBA I TELEFAX: (080)334938 NETWORK ID: SACCONE@VAXBA0.INFNET EARN%IBOINFN::SACCONE%VAXBA0.INFNET (EARNET) PROFESSION: PROFESSOR IN MOLECULAR BIOLOGY GENERAL: MITOCHONDRIAL BIOGENESIS MOLECULAR EVOLUTION NUCLEIC ACID AND PROTEIN DATABASE COMPUTER APPLICATION ON NUCLEIC ACID SEQUENCES $EOD $WRITE SYS$OUTPUT "Creating SHEPHERD." $CREATE SHEPHERD. $DECK From: shepherd@ch.unibas.urz John Shepherd, Biozentrum, Klingelbergstrasse 82, 4056 Basel, Switzerland. $EOD $WRITE SYS$OUTPUT "Creating SKIDMORE." $CREATE SKIDMORE. $DECK NAME: Dr Christopher J. Skidmore ADDRESS: Department of Physiology & Biochemistry University of Reading Whiteknights PO Box 228 Reading RG6 2AJ PHONE: 0734-875123 x 7667 TELEX: 847813 RULIB G NETWORK ID: sasskidm@UK.AC.RDG.AM.CMS CAREER: Interests: Gene expression in the mammary gland, RFLP and fingerprint analysis in animals, comparative chromosome mapping $EOD $WRITE SYS$OUTPUT "Creating TEMMINCK." $CREATE TEMMINCK. $DECK NAME : Bert Temminck ADDRESS: Basel Institute for Immunology Grenzacherstr. 487 CITY : CH-4005 BASEL COUNTRY: SWITZERLAND PHONE : 061 - 492380 PROFESS: System Manager NETWORK Id: BASEL@UTOROCI.BITNET $EOD $WRITE SYS$OUTPUT "Creating VIRDEN." $CREATE VIRDEN. NAME: Dr. Richard VIRDEN COUNTRY: UK PHONE: 091-232-8511 TELEX: 53654 TELEFAX 091-261-1182 NETWORK ID: Janet: BIA3@UK.AC.NCL.MTS CAREER: Interests: Molecular enzymology. $EOD
BIORELAY@BIO.CAM.AC.UK (02/25/88)
From: BIORELAY@BIO.CAM.AC.UK From: <HARPER@EARN.FINUH> 24-FEB-1988 10:50 To: SEQNET Subj: LIFE SCIENTISTS Via: UK.AC.RL.EARN; Wed, 24 Feb 88 10:50:43 GMT Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 8662; Wed, 24 Feb 88 10:50:43 GM Received: from FINUH.BITNET (HARPER) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 8660; Wed, 24 Feb 88 10:50:42 Date: Wed, 24 Feb 88 12:48 O From: <HARPER@EARN.FINUH> Subject: LIFE SCIENTISTS To: seqnet@UK.AC.CAM.BIO X-Original-To: seqnet@bio.cam.ac.uk, HARPER It seems that "life scientists" are really beginning to get organised on the network. I offer the following note for your general information. %%%%%%%%%%%%%%%%%%%%%%%%%%%%EXTRACT%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% Subject: File from LifeSci: "INTRO HELPLSCI" << LifeSci >> Introduction 18 Jan 1988 LifeSci is short for 'The Life Science Research Server' and is a dedicated computer program developed at the Rappaport Institute and running on the main computer at Technion, Israel (RPRLSCI@TECHNION.BITNET). It's purpose is to enhance communication and research among people in the life related fields (medicine, physiology, psychology, social work etc..) who work far from each other and can benefit forming international work groups and 'Think-Tank' with their colleagues. The audience LifeSci was written for know little about computers and are too busy to learn, they want simple access without having to bother with the internal works of the system. General description -=-=-=-=-=-=-=-=-=- o DIGEST server Digests are computerized magazines, they do not appear in paper form but exist as electronic media. A group of people interested in a common topic can create their own little paper, its as simple as saying 'CREATE TOPIC ION-CHANNEL' and every one can do it. Create your own or join an existing topic, a digest can have an editor or be an open forum. Unlike its paper counterparts all digests are archived and indexed and can be retrieved using simple search commands. o NAMES server To locate people from other places according to their name or interest is one of the prime objectives. As you join, you will be asked to fill up a registry form with your vital statistics, interests and area of expertise. o APPLICATION server If you need a special computer program to do a special part of an experiment, preform a special analysis or run laboratory equipment there is a fair chance some one already written it or something similar elsewhere, so why reinvent the wheel? LifeSci will not keep the programs themselves but will keep record of computer applications developed elsewhere with instructions on how to get them, whom to contact and what you need to use it. o CONFERENCE server 'Chatting' is the interactive sending and receiving of computer messages, more then two people can chat using special relay machines. Registered users of LifeSci will be able to hold conferences by calling members of their TOPIC. The discussion of work group can be distributed as a digest to the missing members. o BBOARD Just a small bulletin board to spread the word around, the BBoard is a public clipboard to post messages of public interest. For more information, write me: Electronicly - RPR1ZAK@TECHNION.BITNET Snail Mail - Dr. Ami Zakai, Rappaport Institute of research, P.O.B. 9697 31096 Israel Facsimile - -972-4-521296 attn Zakai Sincerely yours, Ami Zakai
BIORELAY@BIO.CAM.AC.UK (03/02/88)
From: BIORELAY@BIO.CAM.AC.UK From: SYSTEM@UK.AC.BRISTOL.BSA 29-FEB-1988 15:34 To: BIORELAY Subj: Date: 29-FEB-1988 15:37:12 From: SYSTEM@UK.AC.BRISTOL.BSA To: BIORELAY@UK.AC.CAM.BIO One of my collegues who has recently returned from the USA tells me that congress have "agreed, in principal, to fund the human genome sequencing project". I would be most grateful if someone who knows would let me have some hard information on this. A reference to an article in a journal would be nice. Please reply to SYSTEM @ UK.AC.BRIS.BSA Thanks. Andrew Lyall From: mjb1@uk.ac.cam.bio To: SEQNET Subject: Gel reading program for the MAC Date: 27 Feb 1988 Does anyone know of a program for the Apple Macintosh to read Sanger dideoxy DNA sequencing gel autoradiograms using a digitizer? Please let me know if you do. Are there any packages for the Mac other than DNA Inspector and MacGene. Thanks. M.J.Bishop
MJB1@VMS-SUPP.CAM.AC.UK (03/05/88)
From: MJB1@VMS-SUPP.CAM.AC.UK (Message number 9) [ u ] Accepted: 09:21:11 01 Mar 88 Submitted: 12:42:00 26 Feb 88 IPMessageId: <127:linder@urz.unibas.ch> From: linder@ch.unibas.urz To: MJB1@uk.ac.cambridge.phoenix Subject: lys2-reference Received: from Ean.Ean-Relay.AC.UK by Ean-Relay.AC.UK via EAN id aa05074; 29 Feb 88 19:35 GMT Return-Receipt-To: linder@urz.unibas.ch Dear Martin, here again the reference on LYS2: Fleig et al, Gene 46, 237-245, 1986. Sincerely yours Patrick Linder From: STOEHR@UK.AC.AFRC.ARCC 1-MAR-1988 16:23 To: MJB1 Subj: DNA software for MAC Date: 1-MAR-1988 16:23:04 GMT From: STOEHR@UK.AC.AFRC.ARCC To: MJB1@UK.AC.CAM.BIO Subject: DNA software for MAC Martin, Something I was given but not folowed up yet is a list of a few programs adapted for the MAC. MOLGENJR 1.2 DNA Analysis program DNAANALYZE 1.2 " " " t-RNA search programs punyEDIT 1.0 small editor for entering sequences THREEAlign 1.0 aligns 3 protein sequences FASTP 2.1 RDF 2.1 LIBPROT 2.1 extracts a file from protein database PIR Protein database. I have merely copied this from an American MAC-orientated bulletin board entry from Tom Maler (RIORDAN.MALER@BIONET-20.ARPA). He says that you can get the progs from Dr Peter Markiewicz Dept. of Viral Biology USAMRIID Ft. Detrick, MD 21701 (301) 6637241 Peter Stoehr, AFRC Computing Centre
MJB1@VMS-SUPP.CAM.AC.UK (03/05/88)
From: MJB1@VMS-SUPP.CAM.AC.UK From: MJB1@UK.AC.CAM.BIO 5-MAR-1988 12:52 To: MJB1 Subj: Date: 5-MAR-1988 12:50:56 GMT From: MJB1@UK.AC.CAM.BIO To: MJB1@UK.AC.CAM.VMS-SUPP From: <GILBERT@EARN.MITWIBR> 1-MAR-1988 19:03 To: MJB1 Subj: Gel reading software for MAC Via: UK.AC.RL.EARN; Tue, 01 Mar 88 19:03:41 GMT Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 6081; Tue, 01 Mar 88 19:03:41 GM Received: from MITWIBR.BITNET (GILBERT) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 6080; Tue, 01 Mar 88 19:03:41 Date: Tue, 1 Mar 88 12:38 EST From: <GILBERT@EARN.MITWIBR> Subject: Gel reading software for MAC To: mjb1@UK.AC.CAM.BIO X-Original-To: mjb1@bio.cam.ac.uk IBI is getting ready to release it's MAC version of it's IBM software. This should occur sometime this summer. I've seen a very beta copy and it looks alot like the IBM PC "screen". There is a fellow working in MIT's Center for Cancer Research who is working on a program to do cloning. I'm not sure he's ready to release his program and I'm not in a position to make his name public. From: SEQNET@UK.AC.CAM.BIO 5-MAR-1988 12:55 To: MJB1 Subj: Date: 5-MAR-1988 12:54:12 GMT From: SEQNET@UK.AC.CAM.BIO To: MJB1@UK.AC.CAM.VMS-SUPP From: SYSTEM@UK.AC.BRISTOL.BSA 1-MAR-1988 10:38 To: SEQNET Subj: Date: 1-MAR-1988 10:41:05 From: SYSTEM@UK.AC.BRISTOL.BSA To: SEQNET@UK.AC.CAM.BIO One of my collegues who has recently returned from the USA tells me that congress have "agreed, in principal, to fund the human genome sequencing project". I would be most grateful if someone who knows would let me have some hard information on this. A reference to an article in a journal would be nice. Please reply to SYSTEM @ UK.AC.BRIS.BSA Thanks. Andrew Lyall From: DBO@UK.AC.LEICESTER.VAX 1-MAR-1988 12:26 To: SEQNET Subj: Date: 1-MAR-1988 12:24:07 GMT From: DBO@UK.AC.LEICESTER.VAX To: SEQNET@UK.AC.CAM.BIO Re: Directory of email addresses of molecular biologists. Picornavirus Research Group, Microbiology Dept., Univ. of Reading. Postal Address: Department of Microbiology University of Reading London Road READING RG1 5AQ UK Head of Dept. & Group Leader: Prof. J W Almond JWA@UK.AC.LEICESTER.VAX RESEARCH INTERESTS Molecular Virology, Picornaviruses, Protein Engineering, Antigenicity, HIV Microbial Pathogenisis, Vaccines Other Members of Group: Dr. J D Cooper CDJ_F@UK.AC.LEICESTER.VAX Functions of 5' & 3' non-coding regions of picornaviruses Dr. D J Evans DJE_F@UK.AC.LEICESTER.VAX Rhinoviruses, Protein Engineering Dr. O Jenkins OWJ_F@UK.AC.LEICESTER.VAX Coxsackieviruses, Enterovirus 70, Protein Engineering Mr. D H Moon MMM_F@UK.AC.LEICESTER.VAX Protein Engineering, Polioviruses Mr. S R Pollard XER_F@UK.AC.LEICESTER.VAX Molecular basis of attenuation in polio type 2 Mr. J D Booth DBO@UK.AC.LEICESTER.VAX Enterovirus 70, Computers in molecular biology Other members of the group do not have individual email addresses. If you are trying to contact any of the above and having problems then send a message to DBO@UK.AC.LEICESTER.VAX I monitor email much more frequently than the others and am therefore able to reply and bring your message to the intended recipient more rapidly. Dave Booth. From: SEQNET@UK.AC.CAM.BIO 5-MAR-1988 12:57 To: MJB1 Subj: Date: 5-MAR-1988 12:55:46 GMT From: SEQNET@UK.AC.CAM.BIO To: MJB1@UK.AC.CAM.VMS-SUPP From: Ware@UK.AC.AUCC (Georges Ware) 3-MAR-1988 14:52 To: SEQNET Subj: for distribution Date: Thu, 3 Mar 88 14:51 GMT From: Ware@UK.AC.AUCC (Georges Ware) Subject: for distribution To: SEQNET@UK.AC.CAMBRIDGE.BIOLOGY Message-ID: <880303145154.945039@UK.AC.AUCC> CHANGES TO 'BRUNEP' ELECTRONIC JOURNAL at BRISTOL ------------------------------------------------- The new Bulletin Board, in the form of an electronic journal at Bristol can now accept either FULL PAPERS or SUMMARIES of recently published, or future, communications. The Journal is open to receive contributions on any scientific subject. Publication in the Journal is still FREE and submissions are urgently required. The Journal is not a 'chat-show' but BRUNEP now provides facilities, in the form of a 'forum', for more trivial comments and information exchange. Contributions to the Journal, which cannot be entered directely by the contributor, should be sent EITHER by electronic mail to: BRUNEP at UK.AC.BRISTOL OR, by post, as a plain-ASCII text file on IBM-compatible 360Kb 5.25-inch floppy disc, to: The Editor, BRUNEP, The Department of Microbiology, The University of Bristol, BS8 1TD. U.K. (Telephone 272-303500) Papers should preferably be in English, but papers in other European languages may be submitted. The Journal can be read, and users can participate in to the 'forum', by simply logging-in to the Bristol Mainframe. We are connected to the academic network JANET (UK.AC.BRISTOL.MULTICS) and can also be reached from PSS using the JANET gateway address 23421920014869 followed by .00006021000100 On connection to Multics the following 'banner' will be received. --------------------------------------------------------------------------- Multics MR22.0: Avon Universities, Bristol (Channel c.h008) Load = 38.4 out of 160.0 units: users = 34, 01/06/88 1345.6 gmt Wed --------------------------------------------------------------------------- Users should then type 'login BRUNEP' (the abreviation 'l BRUNEP' may also be used) and respond to the password prompt with 'BRUNEP'. (NOTE: 'BRUNEP' must be in upper-case on both occasions.) No prior registration is necessary, and USE OF THE JOURNAL IS FREE and SELF-EXPLANATORY. PAPERS and/or SUMMARIES ARE STILL URGENTLY NEEDED TO GET THE JOURNAL GOING! FURTHER DEATILS CAN BE OBTAINED BY LOGGING-IN TO THE JOURNAL.
MJB1@VMS-SUPP.CAM.AC.UK (03/05/88)
From: MJB1@VMS-SUPP.CAM.AC.UK Here is a list of all entries received to date for the list of European molecular biologists. Please contribute if you have not already done so. Martin Bishop. $WRITE SYS$OUTPUT "Creating ALEFOUNDER." $CREATE ALEFOUNDER. $DECK (1) Electronic mail address: JANET PRA1@CAM.PHX EARN PRA1%CAM.PHX@EARN.RL.AC.UK (2) Name and postal address: Dr. P.R. Alefounder, Department of Organic & Inorganic Chemistry, University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW. (3) Indication of interests: Molecular biology, computers. $EOD $WRITE SYS$OUTPUT "Creating ASHBURNER." $CREATE ASHBURNER. $DECK Michael Ashburner Department of Genetics University of Cambridge Downing Street Cambridge England Telephone 44-(0)223-333969 ma11@uk.ac.cam.phx ashburner@arpa.bionet-20 $EOD $WRITE SYS$OUTPUT "Creating BARCLAY." $CREATE BARCLAY. $DECK From: BARCLAY@UK.AC.OXFORD.VAX 19-JAN-1988 17:31 Dear Martin Bishop, Thank you for the mail and putting us on the Bionet Seqnet and Biotech networks. THey look as if they will be helpful. Congratulations on organising such an interesting IUSC workshop in Cambridge. Yous Sincerely A. Neil Barclay $EOD $WRITE SYS$OUTPUT "Creating BEECHING." $CREATE BEECHING. $DECK NAME: John R. Beeching ADDRESS: Biological Sciences, University of Bath CITY: Bath BA2 7AY COUNTRY: UK PHONE: (0225) 826826 ext. 5193 TELEX: 44097 (UK) NETWORK ID: JANET: JB86@.UK.AC.CAM.PHX PROFESSION: Plant molecular biologist INTERESTS: Plant gene expression, RFLPs, plant tissue culture. $EOD $WRITE SYS$OUTPUT "Creating BEYNON." $CREATE BEYNON. $DECK SB06@UK.AC.LIV.IBM Dr R J Beynon Department of Biochemistry University of Liverpool PO Box 147 LIVERPOOL L69 3BX U.K. Editor Computer Applications in the Biosciences Mammalian proteases and cellular proteolytic processes Protein metabolism in normal and abnormal muscle Glycogen phosphorylase Thaumatin ( a very, very sweet protein!!) Apple Macintosh $EOD $WRITE SYS$OUTPUT "Creating BINGHAM." $CREATE BINGHAM. $DECK Dr. Richard W. Bingham Dept. of Veterinary Pathology Royal (Dick) School of Veterinary Studies University of Edinburgh Summerhall Edinburgh EH9 1QH email: R.W.Bingham @ uk.ac.edinburgh tel: 031-667 1011 Ext. 5281/5283 telex: 727442 (UNIVED G) interests: molecular virology (particularly paramyxoviruses & papillomaviruses); computing $EOD $WRITE SYS$OUTPUT "Creating BISHOP." $CREATE BISHOP. $DECK (1) MJB1@UK.AC.CAM.PHX MJB1@UK.AC.CAM.BIO MJB1@UK.AC.CAM.VMS-SUPP (2) Martin John Bishop University of Cambridge, Computer Laboratory, New Museums Site, Pembroke Street, Cambridge CB2 3QG, UK. (3) DNA and protein sequence analysis, Inference of evolutionary relationships from sequence data, Applications of computers in molecular biology $EOD $WRITE SYS$OUTPUT "Creating BLAIR." $CREATE BLAIR. $DECK BCH6GEB@UK.AC.LEEDS.CMS1 BCH6GEB%LEEDS.CMS1@EARN.RL.AC.UK Dr G Eric Blair, Department of Biochemistry, University of Leeds, Leeds LS2 9JT, U.K. Interests: eukaryotic transcription transcription factors & their interaction with DNA oncogenic transformation of mammalian cells molecular biology of human adenoviruses myelin gene expression $EOD $WRITE SYS$OUTPUT "Creating BOOTH." $CREATE BOOTH. $DECK Picornavirus Research Group, Microbiology Dept., Univ. of Reading. Postal Address: Department of Microbiology University of Reading London Road READING RG1 5AQ UK Head of Dept. & Group Leader: Prof. J W Almond JWA@UK.AC.LEICESTER.VAX RESEARCH INTERESTS Molecular Virology, Picornaviruses, Protein Engineering, Antigenicity, HIV Microbial Pathogenisis, Vaccines Other Members of Group: Dr. J D Cooper CDJ_F@UK.AC.LEICESTER.VAX Functions of 5' & 3' non-coding regions of picornaviruses Dr. D J Evans DJE_F@UK.AC.LEICESTER.VAX Rhinoviruses, Protein Engineering Dr. O Jenkins OWJ_F@UK.AC.LEICESTER.VAX Coxsackieviruses, Enterovirus 70, Protein Engineering Mr. D H Moon MMM_F@UK.AC.LEICESTER.VAX Protein Engineering, Polioviruses Mr. S R Pollard XER_F@UK.AC.LEICESTER.VAX Molecular basis of attenuation in polio type 2 Mr. J D Booth DBO@UK.AC.LEICESTER.VAX Enterovirus 70, Computers in molecular biology Other members of the group do not have individual email addresses. If you are trying to contact any of the above and having problems then send a message to DBO@UK.AC.LEICESTER.VAX I monitor email much more frequently than the others and am therefore able to reply and bring your message to the intended recipient more rapidly. Dave Booth. $EOD $WRITE SYS$OUTPUT "Creating CASEY." $CREATE CASEY. $DECK NAME Rod Casey ADDRESS John Innes Institute, Colney Lane, Norwich, NR4 7HU, UK. PHONE (0603) 52571 TELEX 975122 JIINOR G TELEFAX (0603) 56844 NETWORK CASEY@UK.AC.AFRC.JII PROFESSION Biochemist CAREER Variation in the structure and synthesis of proteins GENERAL Molecular genetics. Protein structure and synthesis, especially seed proteins, including storage proteins, lectins, trypsin inhibitors and lipoxygenases. $EOD $WRITE SYS$OUTPUT "Creating CLAVERIE." $CREATE CLAVERIE. $DECK NAME: Jean-Michel Claverie ADDRESS: Computer Science Unit, Institut Pasteur, 28 rue Dr Roux CITY: 75724 - PARIS, cedex 15. COUNTRY: FRANCE PHONE: (33)(1)45 68 85 10 TELEX: 250609F TELEFAX: (33)(1)43 06 98 35 NETWORK IDS: JMC@PASTEUR PROFESSION: Head, Computer Science Unit, Institut Pasteur CAREER: General Biocomputing, sequence analysis, databank (PGtrans, PseqIP), molecular modelling, immunology, AIDS. GENERAL: Most active research: T-immunogenicity, AIDS, molecular modelling HARWARE: DATA GENERAL MV8000/10000, MicroVAXII, E&S PS390, PCs, MacInt. LANGAGE: FORTRAN77, C, PASCAL, ORACLE, INGRES. SOFTWARE: Complete Sequence Analysis (SASIP), Staden, PCgene, Lipman, ... DATABANKS: GenBank, EMBL, NBRF-PIR, PGtrans, PSD-Kyoto, Newat, PSeqIP, Swiss-Prot. $EOD $WRITE SYS$OUTPUT "Creating COULSON." $CREATE COULSON. $DECK NAME: A.F.W.Coulson@uk.ac.edinburgh (JANET) ADDRESS: Dept of Molecular Biology, Univ of Edinburgh CITY: King's Buildings, Mayfield Rd, Edinburgh EH9 3JR COUNTY: ! ! COUNTRY: United Kingdom PHONE: 031 667 1081 Ext 2723 TELEX: 727442 (UNIVED G) TELEFAX: ! ! NETWORK IDS: a.coulson@uk.ac.edinburgh PROFESSION: Joint Director, Biocomputing Research Unit CAREER: Computing for molecular biology, protein engineering, beta-lactamases GENERAL: ! ! $EOD $WRITE SYS$OUTPUT "Creating DALGLEISH." $CREATE DALGLEISH. $DECK From: RAY@UK.AC.LEICESTER.VAX 19-JAN-1988 12:30 To: MJB1 Subj: Date: 19-JAN-1988 12:16:16 GMT From: RAY@UK.AC.LEICESTER.VAX To: mjb1@UK.AC.CAM.VMS-SUPP Martin, I have tried to find out from our computer staff if it is possible to use the new EMBL file server from Leicester. They say not since JANET uses an X.25 protocol that is incompatible with the requirements of the process. What do you suggest for those of us who are not hard-wired to EARN. Cheers, Raymond Dalgleish. PS please add me to the list of people who wanted to keep in touch following the meeting the other week. Details:- Dr.Raymond Dalgleish, Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, U.K. Tel 44 (0533) 523425 E-mail ray@uk.ac.le.vax Interests:- Inherited human connective tissue disorders including Marfan syndrome, osteogenesis imperfecta and the Ehlers-Danlos syndromes. I am co- manager of the Molecular Biology Users Group (MBUG) on the VAX at Leicester. $EOD $WRITE SYS$OUTPUT "Creating DESSIN." $CREATE DESSIN. $DECK Name: Phillipe Dessen Address: Laboratoire de Biochemie, Ecole Polytechnique City: 91128 PALAISEAU Cedex Country: France Phone: 69 41 82 00 x2841 Network: frors31@earn.ubch000 Interests: Biochemistry of the aminoacyl-tRNA synthetases: structure, function and regulation. DNA and protein sequence analysis, databanks. $EOD $WRITE SYS$OUTPUT "Creating DOELZ." $CREATE DOELZ. $DECK From: doelz@ch.unibas.urz Dr. Reinhard Doelz Biophysics Department - Biocomputing BIOZENTRUM Klingelbergstr. 70 CH-4056 BASEL $EOD $WRITE SYS$OUTPUT "Creating ELDER." $CREATE ELDER. $DECK NAME: JK Elder ADDRESS: Department of Biochemistry, University of Oxford CITY: Oxford OX1 3QU COUNTRY: UK PHONE: +44-(0)865-275228 TELEX: 83681 (UK) NETWORK IDS: JANET: elder@uk.ac.ox.vax EARN: elder%ox.vax@earn.rl.ac.uk GENERAL: Automatic construction of restriction maps Automatic sequencing Image processing Molecular biology software which runs on Suns and/or under UNIX $EOD $WRITE SYS$OUTPUT "Creating EMMERSON." $CREATE EMMERSON. $DECK NAME: Prof. Peter T. Emmerson ADDRESS: Dept. Biochemistry, University of Newcastle upon Tyne CITY: Newcastle upon Tyne, NE2 4HH COUNTY: Tyne and Wear COUNTRY: UK PHONE: 091-232-8511 TELEX: 53654 TELEFAX 091-261-1182 NETWORK ID: Janet: BIB3@UK.AC.NCL.MTS CAREER: Interests: DNA repair. Genetic recombination. Molecular biology of paramyxoviruses. $EOD $WRITE SYS$OUTPUT "Creating EVANS." $CREATE EVANS. $DECK Dear Dr Bishop, I am interested in keeping in touch with the development of molecular biology computing, although I am not active in this area. My interest stems from running the scientific side of Cray X-MP support at RAL and I would like to help in the use of supercomputers wherever appropriate. The information requested in your note is: (1) RGE@UK.AC.RL.IB (2) Dr R G Evans, Rutherford Appleton Laboratory Chilton, Didcot OX11 0QX tel 0235 21900ext5656 (3) Interested in new and developing areas of supercomputer applications. $EOD $WRITE SYS$OUTPUT "Creating FARRALL." $CREATE FARRALL. $DECK Martin Farrall Department of Biochemistry and Molecular Genetics St. Mary's Hospital Medical School Norfolk Place London W2 1PG (01) 723 1252 rkbc110@uk.ac.lon.smhms.ux Molecular genetics of cystic fibrosis DNA/protein sequence analysis Computational methods in human genetic linkage analysis $EOD $WRITE SYS$OUTPUT "Creating HAMES." $CREATE HAMES. $DECK In connection with SEQNET bulletin no.52, 8.1.88 herewith 1 more name for inclusion in Mol. Biol. interest list: DRBDH@UK.AC.LEEDS.BIOVAX DRBDH%LEEDS.BIOVAX@UK.AC.RL.EARN Dr B David Hames, Department of Biochemistry, University of Leeds, Leeds LS2 9JT, U.K. Interests: eukaryotic transcription molecular biology of development homeobox gene function in vertebrates Dictyostelium ------------- Xenopus ------- $EOD $WRITE SYS$OUTPUT "Creating HARPER." $CREATE HARPER. $DECK NAME: Robert Harper (HARPER@finfun FINLAND) ADDRESS: University of Helsinki, Department of Microbiology CITY: SF-00710 HELSINKI 71 COUNTY: --------------------------- COUNTRY: FINLAND PHONE: +358 0 378011/466 (work) 308627 (home) TELEX: 124 690 UNIH SF (FINLAND) TELEFAX: 374 1520 NETWORK IDS: HARPER@finfun PROFESSION: Microbiologist (Lactobacillus research and fermentation) CAREER: Biotechnology and Information Technology. GENERAL: Sleeping, Gardening, Public Domain software. $EOD $WRITE SYS$OUTPUT "Creating HARWOOD." $CREATE HARWOOD. $DECK NAME: Dr. Colin R. Harwood ADDRESS: Dept. Microbiology, University of Newcastle upon Tyne CITY: Newcastle upon Tyne, NE2 4HH COUNTY: Tyne and Wear COUNTRY: UK PHONE: 091-232-8511 TELEX: 53654 TELEFAX 091-261-1182 NETWORK ID: Janet: mma4@UK.AC.NCL.MTS CAREER: Interests: Gene expression and protein export in gram positive bacteria. $EOD $WRITE SYS$OUTPUT "Creating HECKELS." $CREATE HECKELS. $DECK FROM:- DR. J.E.HECKELS DEPARTMENT OF MICROBIOLOGY UNIVERSITY OF SOUTHAMPTON MEDICAL SCHOOL EMAIL:- FMI019@SOTON.IBM DEAR Dr. Bishop, I have read with interest recent articles in Binary concerning the Seqnet bulletin board for molecular biologists. In this department myself and several collegues are involved in cloning and sequencing the surface proteins of a number of pathogenic bacteria and viruses. I feel that we are not yet making fullest use of data and programmes which may be available elsewhere. I would therefore be grateful if it were possible for me to recieve the information on the seqnet bulletin board. I have also seen in Binary a list of molecular biology programmes which are available for PCs and I would be grateful for any further information if this has been updated recently. Thank you in advance for your help. Yours sincerely John Heckels $EOD $WRITE SYS$OUTPUT "Creating HERRIES." $CREATE HERRIES. $DECK BCH6DGH@UK.AC.LEEDS.CMS1 BCH6DGH%LEEDS.CMS1@EARN.RL.AC.UK Dr David G Herries, Department of Biochemistry, University of Leeds, Leeds LS2 9JT, U.K. Interests: computer applications in biochemistry $EOD $WRITE SYS$OUTPUT "Creating HIGGINS." $CREATE HIGGINS. $DECK NAME: DESMOND HIGGINS ADDRESS: TRINITY COLLEGE, DUBLIN 2. DEPARTMENT OF GENETICS CITY: DUBLIN COUNTRY: IRELAND PHONE: +353 1 772941 /1969 TELEX: 93782 TCD EI (IRELAND) TELEFAX: 772694 NETWORK ID: D.HIGGINS@IRL.HEA.TCD.DEC20 PROFESSION: RESEARCH FELLOW GENERAL: DNA/PROTEIN SEQUENCE ANALYSIS AND DATABASES, EVOLUTION, INSECT TAXONOMY. $EOD $WRITE SYS$OUTPUT "Creating HOLBROOK." $CREATE HOLBROOK. $DECK 1. JANET: HOLBROOK@UK.AC.BRISTOL.BSA 2. Dr J. John HOLBROOK, Department of Biochemistry, University of Bristol Medical School, BRISTOL BS8 1TD, U.K. 3. Protein, especially redox enzyme, design and construction. 4. It would help if the one of my long term collabroators were also included, with an otherwise analogous entry: Dr. A.R. CLARKE: CLARKEAR@UK.AC.BRISTOL.BSA $EOD $WRITE SYS$OUTPUT "Creating HOLMES." $CREATE HOLMES. $DECK NAME: EDDIE HOLMES ADDRESS: DEPT. OF ZOOLOGY, UNIVERSITY OF CAMBRIDGE, DOWNING STREET, CAMBRIDGE, CB2 3EJ. COUNTRY: UK PHONE: 0223-336650 NETWORK ID: EH102@UK.AC.CAM.PHX PROFESSION: LOWLY RESEARCH STUDENT RESEARCH MOLECULAR EVOLUTION, MAMMALIAN EVOLUTION, PROBABILISTIC INTERESTS: MODELLING, CLASSIFICATION, PROSIMIANS. $EOD $WRITE SYS$OUTPUT "Creating HUGHES." $CREATE HUGHES. $DECK NAME: Dr. Monica Hughes ADDRESS: Dept. Genetics, University of Newcastle upon Tyne CITY: Newcastle upon Tyne, NE2 4HH COUNTY: Tyne and Wear COUNTRY: UK PHONE: 091-232-8511 TELEX: 53654 TELEFAX 091-261-1182 NETWORK ID: Janet: mma4@UK.AC.NCL.MTS CAREER: Interests: Higher plant molecular genetics, stress responses, cyanide metabolism. $EOD $WRITE SYS$OUTPUT "Creating JACKMAN." $CREATE JACKMAN. $DECK Jackman@UK.AC.AFRC.FRIN Dialcom 42:CDT0013 Dr.Peter J.H.Jackman National Collection of Yeast Cultures, AFRC Inst of Food Research, Colney Lane, Norwich, NR4 7UA Norfolk, UK Curator National Collection of Yeast Cultures & National Collection of Food Bacteria. Member committee Society for General Microbiology Computer Club, Member committee Microbial Strain Data Network interests molecular systematics,computing in microbiology,strain databases $EOD $WRITE SYS$OUTPUT "Creating KELL." $CREATE KELL. $DECK From: DBK@UK.AC.ABERYSTWYTH In response to today's, I presently act as the main node at UCW for biological bboard services, and this will continue pro tem. When my colleague sget more into it they will doubtless join directly. However, please keep me on the list for SEQNET info. (1) DBK@ABER.V (2) Dr Douglas B. Kell, Dept of BOtany & Microbiology, University College of Wales, ABERYSTWYTH, Dyfed SY23 3DA. (3) Interests: keeping abreast with everything relevant in mol. biol., but especially protein behaviour and use of micro's to understand it. Best wishes for 1988! $EOD $WRITE SYS$OUTPUT "Creating KNEALE." $CREATE KNEALE. $DECK Please include me in your list of molecular biology network users: Dr Geoff Kneale Biophysics Laboratories Portsmouth Polytechnic Portsmouth PO1 2DT GGK1@PORTSMOUTH.CSOVAX AREAS OF INTEREST: DNA binding proteins, Protein Engineering, Filamentous Bacteriophage, Biophysics (Spectroscopy and Diffraction). $EOD $WRITE SYS$OUTPUT "Creating LLOYD." $CREATE LLOYD. $DECK From: Andrew_T_Lloyd @ UK.AC.NEWCASTLE 20-JAN-1988 11:35 Greetings, Can you put me on your mailing list for SEQNET and all that Mol Biol chitchat that I currently get via Julie Glanville in Microbiology Newcastle? I guess my address will get appended by our computer Regards, Andrew T. Lloyd, Genetics, Newcastle. $EOD $WRITE SYS$OUTPUT "Creating MCFERRAN." $CREATE MCFERRAN. $DECK Here is my E-Mail address at Queen's, for the list of European Mol. Biols.: ABJA1248@UK.AC.QUEENS-BELFAST.CENTRE.VAX sorry it seems a bit of a mouthfull, the postal one isn't much better: Dr. N.V.McFerran Department of Biochemistry The Queen's University of Belfast Medical Biology Centre 97 Lisburn Rd. BELFAST BT9 7BL N. Ireland. Interests include struct/fn relationships in proteins, notably proteases & dehydrogenases, image analysis applications & lab automation. Many thanks for the organisational effort last week, all the best for '88. Neil McFerran. $EOD $WRITE SYS$OUTPUT "Creating MELVIN." $CREATE MELVIN. $DECK *name Melvin,W.T. With reference to your message of 8 Jan; Electronic mail address W.T.MELVIN@UK.AC.ABDN Postal address Dr W.T. Melvin Dept. of Biochemistry University of Aberdeen Marischal College Aberdeen, AB9 1AS U.K. Tel No. 0224 273110 Interests Molecular biology of cytochrome P450 and DNA polymerase alpha $EOD $WRITE SYS$OUTPUT "Creating MILANESI." $CREATE MILANESI. $DECK (1) MILANESI@ICILVX.INFNET (2) LUCIANO MILANESI Istituto di Tecnologie Biomediche Avanzate C.N.R. Via Ampere 56 20133 - MILANO (ITALY) (3) Nucleic acid and protein database Computer application on nucleic acid sequences $EOD $WRITE SYS$OUTPUT "Creating MILLNER." $CREATE MILLNER. $DECK BCH6PAM@UK.AC.LEEDS.CMS1 BCH6PAM%LEEDS.CMS1@EARN.RL.AC.UK Dr PauL A Millner, Department of Biochemistry, University of Leeds, Leeds LS2 9JT, U.K. Interests: signal transducing proteins plant molecular biology $EOD $WRITE SYS$OUTPUT "Creating MURRAYRUST." $CREATE MURRAYRUST. $DECK Peter Murray-Rust Glaxo Group Research Greenford Road MIDDX UB6 0HE PMR1716@UK.CO.GLAXO You might well encounter some problems mailing to this address: - We are commercial and there might be political problems (I hope not) - Part of the transmission has to involve PSS (I think BT insist) and this probably means someone has to pay - Our X25 is problematical at present! I am however very keen on developing an electronic Club for UK macromolecualr sc s to the Protein Engineering Club. IWe are also hoping to mount our software at daresbury soon (as well as distribu ting it more widely) and hope that that might become some sort of focus. Do you run any sort of interactive bulletin board at Cambridge or is it all by mail to identified recipients? For this year (1988) I am seconded to York and it is probably safer to mail me PMR@UK.AC.YORK.YORVIC Peter Murray-Rust $EOD $WRITE SYS$OUTPUT "Creating PARTIS." $CREATE PARTIS. $DECK NAME: Dr Mick Partis ADDRESS: Biochemistry & Molecular Biology, Institute of Horticultural Research, Worthing Road CITY: Littlehampton COUNTY: W. Sussex. BN17 6LP. COUNTRY: U.K. PHONE: 0903-716123 TELEX: ! TELEFAX: 0903-726780 NETWORK PARTIS @UK.AC.AFRC.GCRI PROFESSION: Biochemist INTERESTS: Protein & Nucleic acid Sequence Analysis. Plant Molecular Biology. GENERAL: This address can be used to contact my colleagues Dr B. Thomas and Dr B. Jordan. $EOD $WRITE SYS$OUTPUT "Creating PFEIFFER." $CREATE PFEIFFER. $DECK The members of the MIPS protein sequence database would like to participate in the European electronic mailing address list: MIPS postal address is: MIPS (Martinsried Institute for Protein Sequence Data) Max-Planck-Institute for Biochemistry Am Klopferspitz 18 D-8033 Martinsried FRG Current members are: Dr. Friedhelm Pfeiffer Dr. Hans Werner Mewes Electronic Mailing addresses are: MIPS@dm0mbp51.BitNet sequence submission and general information Pfeiffer@dm0mpb51.BitNet personal messages, VecBase, restriction enzymes Mewes@dm0mpb51.BitNet personal messages MIPS interest: MIPS is a protein sequence database that will collect and distribute protein sequences within the frame of a protein sequence database consortium. The three current members are MIPS at Max-Planck-Inst. Biochemie, Martinsried, FRG, in Europe PIR at MBRF (Nat. Biomed. Res. F.), Washington, USA, in America JIPID at Science University, Tokyo, Japan, in Asia The members of this consortium will prepare one common sequence data set. This will be an extension of the current PIR protein sequence database. Data submission and comments via electronic mailing are highly recommended. Please send SeqNet mail to user "MIPS" in the future and discontinue sending to "PFEIFFER" and "MEWES". Yours sincerely Friedhelm Pfeiffer $EOD $WRITE SYS$OUTPUT "Creating SACCONE." $CREATE SACCONE. $DECK NAME: CECILIA SACCONE ADDRESS: DIPARTIMENTO DI BIOCHIMICA E BIOLOGIA MOLECOLARE UNIVERSITA' DI BARI, VIA AMENDOLA 165/A 70126 BARI (ITALY) CITY: BARI COUNTRY: ITALY PHONE: (080)243303 TELEX: 810333 PHISBA I TELEFAX: (080)334938 NETWORK ID: SACCONE@VAXBA0.INFNET EARN%IBOINFN::SACCONE%VAXBA0.INFNET (EARNET) PROFESSION: PROFESSOR IN MOLECULAR BIOLOGY GENERAL: MITOCHONDRIAL BIOGENESIS MOLECULAR EVOLUTION NUCLEIC ACID AND PROTEIN DATABASE COMPUTER APPLICATION ON NUCLEIC ACID SEQUENCES $EOD $WRITE SYS$OUTPUT "Creating SHARP." $CREATE SHARP. $DECK NAME: PAUL SHARP ADDRESS: TRINITY COLLEGE, DUBLIN 2. DEPARTMENT OF GENETICS CITY: DUBLIN COUNTRY: IRELAND PHONE: +353 1 772941 /1035 TELEX: 93782 TCD EI (IRELAND) TELEFAX: 772694 NETWORK ID: P.SHARP@IRL.HEA.TCD.DEC20 PROFESSION: LECTURER IN GENETICS GENERAL: DNA SEQUENCE ANALYSIS, MOLECULAR EVOLUTION, CODON USAGE, HIV, YEAST, BACILLUS, UBIQUITIN. $EOD $WRITE SYS$OUTPUT "Creating SHEPHERD." $CREATE SHEPHERD. $DECK From: shepherd@ch.unibas.urz John Shepherd, Biozentrum, Klingelbergstrasse 82, 4056 Basel, Switzerland. $EOD $WRITE SYS$OUTPUT "Creating SKIDMORE." $CREATE SKIDMORE. $DECK NAME: Dr Christopher J. Skidmore ADDRESS: Department of Physiology & Biochemistry University of Reading Whiteknights PO Box 228 Reading RG6 2AJ PHONE: 0734-875123 x 7667 TELEX: 847813 RULIB G NETWORK ID: sasskidm@UK.AC.RDG.AM.CMS CAREER: Interests: Gene expression in the mammary gland, RFLP and fingerprint analysis in animals, comparative chromosome mapping $EOD $WRITE SYS$OUTPUT "Creating STOEHR." $CREATE STOEHR. $DECK From: STOEHR@UK.AC.AFRC.ARCC To: SEQNET@UK.AC.CAM.PHX I would like to participate in the great European database in the sky. (1) STOEHR @UK.AC.AFRC.ARCC (2) Peter J. Stoehr Applications Development AFRC Computing Centre West Common Harpenden Hertfordshire AL5 2JE Tel. 05827-62271 (3) Computing Service/Support for Molecular Biology also (1) OWEN @UK.AC.AFRC.ARCB (note B) (2) Dr John Owen (same address) (3) Computing Service/Support for Graphics, Molecular modelling Peter J Stoehr $EOD $WRITE SYS$OUTPUT "Creating SUMMERS." $CREATE SUMMERS. $DECK *name Summers,D.K. I would like to participate in the European Directory. My address: DKS11@UK.AC.CAM.PHX David K. Summers Dept of Genetics Cambridge University Downing St Cambridge CB2 3EH Interests: Molecular biology of E. coli plasmids Site specific recombination DNA bending $EOD $WRITE SYS$OUTPUT "Creating SUSSMAN." $CREATE SUSSMAN. $DECK *name Sussman,J. Prof. Joel L. Sussman Dept. of Structural Chemistry Weizmann Institute of Science Rehovot 76100 ISRAEL CSJOEL@WEIZMANN (Bitnet) telephone 972-8-482638 or 972-8-483361 interest: X-ray crystallography of DNA & Proteins Cryogenic X-ray crystallography of Proteins & DNA Protein & DNA model building & refinement Structural studies of halophilic proteins $EOD $WRITE SYS$OUTPUT "Creating TEMMINCK." $CREATE TEMMINCK. $DECK NAME : Bert Temminck ADDRESS: Basel Institute for Immunology Grenzacherstr. 487 CITY : CH-4005 BASEL COUNTRY: SWITZERLAND PHONE : 061 - 492380 PROFESS: System Manager NETWORK Id: BASEL@UTOROCI.BITNET $EOD $WRITE SYS$OUTPUT "Creating TOUZEL." $CREATE TOUZEL. $DECK I would like to participate and to enter your mail list. Electronic mail address : Touzel at FRINRA72 (EARN) Name : Jean Pierre TOUZEL Postal address : INRA, Station de Technologie Alimentaire, B.P. 39, F-59651 Villeneuve d'Ascq Cedex (France) Interests : Methane bacteria, Formate dehydrogenase cloning $EOD $WRITE SYS$OUTPUT "Creating VANLEUVEN." $CREATE VANLEUVEN. $DECK PLEASE KEEP ME POSTED ON ANY DEVELOPMENTS I,N THE FIELD OF MOLECULAR BIOLOGY.MY POSTAL ADDRESS IS FRED VAN LEUVEN DEPT OF HUMAN GENETICS -UNIV OF LEUVEN GASTHUISBERG ON6 B3000 LEUVEN BELGIUM. Acknowledge-To: <FRED@BLEKUL13> $EOD $WRITE SYS$OUTPUT "Creating VANORMONDT." $CREATE VANORMONDT. $DECK NAME: Hans van Ormondt(EARN WMBORMOND@HLERUL52) ADDRESS: Sylvius Laboratories, Univ. of Leiden, P.O.Box 9503 CITY: 2300 RA Leiden COUNTY: COUNTRY: The Netherlands PHONE: 31 71 276034 TELEX: TELEFAX: 31 71 276292 NETWORK IDS: EARN PROFESSION: Biochemist CAREER: Gene therapy; DNA software GENERAL: AtariST $EOD $WRITE SYS$OUTPUT "Creating VIRDEN." $CREATE VIRDEN. $DECK NAME: Dr. Richard VIRDEN COUNTRY: UK PHONE: 091-232-8511 TELEX: 53654 TELEFAX 091-261-1182 NETWORK ID: Janet: BIA3@UK.AC.NCL.MTS CAREER: Interests: Molecular enzymology. $EOD $WRITE SYS$OUTPUT "Creating WETHERILL." $CREATE WETHERILL. $DECK I would like to remain on the SEQNET mailing list. electronic mail address :- sta019 @ uk.ac.afrc.sass Graham Wetherill, Scottish Agricultural Statistics Service, King's Buildings, Mayfield Road, Edinburgh, UK, EH9 3JZ TEL: 031-667 1081 ext 2921 TELEX: 727442 (UNIVED G) FAX: 031-667 7938 my initerests are in Statistical and computing support and related research. $EOD $WRITE SYS$OUTPUT "Creating WINKLER." $CREATE WINKLER. $DECK From: A8451DAB@EARN.AWIUNI11 The yeast molecular genetics group at the Department of general biochemistry at the University of Vienna is interested in participating in your interest group. We are mainly working on the regulation of expression of catalase in Saccharomyces cerevisiae. We do this by studying effects on expression of mutations in the promoter region of catalase T A second group in our lab is characterizing and purifying proteins that bind to the upstream promoter region of catalase T. My name is Hans Winkler and I am responsible for E-mail in our lab. The head of our group and also head of the department in Prof. Dr. Helmut Ruis. Our Inst. f. allgemeine Biochemie, Waehringerstr. 38, A-1090 Wien. Austria. Our E-mail address is: A8451DAB at AWIUNI11 Regards, Hans Winkler $EOD
BIORELAY@BIO.CAM.AC.UK (03/10/88)
From: BIORELAY@BIO.CAM.AC.UK From: A.F.W.Coulson @ uk.ac.edinburgh 9-MAR-1988 13:51 Date: 09 Mar 88 13:51:22 gmt Subject: Could you please..... ..... distribute the following notice via SEQNET? Thanks. Andrew. COMPUTER APPLICATIONS FOR BIOTECHNOLOGY A one day course on Computer Applications for Biotechnology will be held in the William Robertson Building, University of Edinburgh, George Square, Edinburgh on Wednesday 6th April 1988. Programme Protein Sequence Analysis A.F.W.Coulson (University of Edinburgh) Nucleic Acid Sequence Analysis J.F.Collins (University of Edinburgh) Molecular Modelling P.Murray-Rust (Glaxo Group Research) Molecular Mechanics D.Osguthorpe (University of Bath) NMR of Proteins A.J.Wilkinson (ICI) Epitope Prediction B.Robson (University of Manchester) Registration The course fee of #25 (#10 for registered postgraduate students) includes a set of Course Notes, lunch, coffee and tea. Registrations for the course (enclosing a cheque payable to 'Heriot-Watt University') should be sent to Prof. C.M.Brown, Dept of Biological Sciences, Heriot-Watt University, Chambers Street, Edinburgh EH1 1HX.
BIORELAY@BIO.CAM.AC.UK (03/10/88)
From: BIORELAY@BIO.CAM.AC.UK From: SJ@UK.AC.CAM.MRC-LMB 9-MAR-1988 16:36 To: SEQNET Subj: Martin, could you please put this out via SEQNET? Thanks. Steve. Date: 9-MAR-1988 16:34:08 From: SJ@UK.AC.CAM.MRC-LMB To: SEQNET@UK.AC.CAM.BIO Subject: Martin, could you please put this out via SEQNET? Thanks. Steve. Does anyone know of, (or better still have) sequence manipulation and/or analysis software that runs on a SUN ( or UNIX machines generally). Public domain would be ideal but it would be nice to have people's views of commercial products too. Thanks in advance. Steve Jones. Molecular Genetics Unit, Laboratory of Molecular Biology. Hills Road. Cambridge. CB2 2QH ENGLAND. (0)223 248011 ex 300 E-mail SJ@UK.AC.CAM.MRC-LMB
BIORELAY@BIO.CAM.AC.UK (03/11/88)
From: BIORELAY@BIO.CAM.AC.UK Date: Thu, 10 Mar 88 18:35:46 MST From: cb@intron.LANL.GOV (Christian Burks) Message-Id: <8803110135.AA07551@intron.lanl.gov> To: BIORELAY@bio.cam.ac.uk Subject: Re: SEQNET Bulletin RELAY ONLY: reply to SEQNET@UK.AC.CAM.BIO Cc: cb Sun analysis software... Try Prophet II from BBN some (or all???) of the IntelliGenetics software Charlie Lawrences "Eugene" package Hugo Martinez's package (he's at UCSF) - cb
BIORELAY@BIO.CAM.AC.UK (03/15/88)
From: BIORELAY@BIO.CAM.AC.UK $WRITE SYS$OUTPUT "Creating JONES_STEVE." $CREATE JONES_STEVE. $DECK NAME: !Steve Jones (SJ@UK.AC.CAM.MRC-LMB) ! ADDRESS: !Molecular Genetics Unit, Medical Research Council ! CITY: !Hills Road. CAMBRIDGE ! COUNTY: ! ! COUNTRY: !ENGLAND ! PHONE: !+223 248011 ex 300 ! TELEX: !81532 ! TELEFAX: !+223 213556 ! NETWORK IDS: !SJ@UK.AC.CAM.MRC-LMB ! PROFESSION: !Molecular biologist ! CAREER !Genome mapping. Molecular biology applied to ! GENERAL: !reproductive biology. ! $EOD $WRITE SYS$OUTPUT "Creating STADEN." $CREATE STADEN. $DECK NAME: !Rodger Staden ! ADDRESS: !MRC Laboratory of Molecular Biology ! CITY: !Hills Road. CAMBRIDGE CB2 2QH ! COUNTY: ! ! COUNTRY: !ENGLAND ! PHONE: !0223 248011 ! TELEX: !81532 ! TELEFAX: !0223 213556 ! NETWORK IDS: !RS@UK.AC.CAM.MRC-LMB ! PROFESSION: !Molecular biologist ! INTERESTS: !Development of computer methods for handling and ! INTERESTS: !analysing nucleic acid and protein sequences ! $EOD $WRITE SYS$OUTPUT "Creating WALMSLEY." $CREATE WALMSLEY. $DECK HELLO, I'm a European Molecular Biologist, and would be happy to be included in your directory; EMAIL ymumrm@uk.ac.umist Address Richard M Walmsley Dept Biochem. and Applied Molecular Biology UMIST PO Box88 Manchester M60 1QD 061 236 3311 ex 2172 Interests Yeast Molecular Biology - Telomeres, Z-DNA, Cell Cycle. I look forward to hearing from you details of the distribution and use of your directory Cheers, Richard. $EOD $WRITE SYS$OUTPUT "Creating ZORN." $CREATE ZORN. $DECK I send some addresses to the Address list of European Molecular Biologists. 1. Electronic Billboard and Service Machine gives access to EMBL/PIR/SWISSPROT sequence data libs; a library for biochemical literature BIOLIT, a growing program library and an electronic billboard receiving the bulletins from BIONET/BIOTECH/SEQNET and from a local Vienna Billboard. The best address to contact anyone in VIENNA / AUSTRIA. Email: A5161DAE@AWIUNI11.EARN Biological Information Online services 2. Manfred ZORN, MSc. Institute of Biochemistry, University Vienna Waehringer Str. 17 A-1090 Vienna / AUSTRIA phone: ++43 222 436141 56 email: A5161DAB@AWIUNI11.EARN Interests: Structure prediction, molecular biology of picornaviruses, responisible for computer applications in our lab. 3. Klaus HARTMUTH, MSc. Institute of Biochemistry, University Vienna Waehringer Str. 17 A-1090 Vienna / AUSTRIA phone: ++43 222 436141 56 email: A5161DAD@AWIUNI11.EARN Interests: Splicing, splicing, splicing, ...... responisible for computer applications in our lab. 4. Dieter BLAAS, PhD. Institute of Biochemistry, University Vienna Waehringer Str. 17 A-1090 Vienna / AUSTRIA phone: ++43 222 436141 54 email: A5161DAA@AWIUNI11.EARN Interests: Molecular biology and immunology of picornaviruses (rhino) $EOD
BIORELAY@BIO.CAM.AC.UK (03/17/88)
From: BIORELAY@BIO.CAM.AC.UK From: UBCH000@EARN.FRORS31 16-MAR-1988 13:12 For distribution as a SEQNET Bulletin. ============================================================================= = INFORMATION ON B.I.S.A.N.C.E = B.I.S.A.N.C.E. is a french project allowing access (via TRANSPAC network) to the nucleotide and protein sequence databases. It is located at CITI2, a computer center which was chosen by the French Ministry of Research as a national host in this field. The 3 on line databases (EMBL, GENBANK, NBRF-PIR) are structurated with ACNUC, a database structure and retrieval software, that allows sequence retrieval on a multi-criterion basis. Moreover, due to the ACNUC structure, access to sub-sequences that code for a specific product (protein, tRNA,..) is provided. On this basis, all sub-sequences coding for proteins in Genbank era obtained directly in protein code (GENPRO database). = Access to more than 130 programs are menu driven (1 main menu and 11 secondary menus): databases retrieval, sequence editing, shotgun method, statistical analysis, prediction of secondary nucleic or protein secondary structures, similarities between sequences, restriction mapping, translation, rapid search in databases, immediat access to exact string in database sequences, phylogeny.. = Access to the Protein data bank and to a bibliographic database of more than 90000 entries (summaries of 75 journals since 1985) complete the project. The service is operational since 1984. Actually, more than 210 academic or industrial groups are daily working on the system, installed on the DPS8 Honeywell-Bull computer at the CITI2 center. Unfortunally, there is not yet an EARN node on this computer. = For more information or connection, please contact : Claude MUGNIER, CITI2, 45 rue des Saints-Peres, 75270 PARIS Cedex 06, France. or Philippe DESSEN , Laboratoire de Biochimie, Ecole Polytechnique, 91128 PALAISEAU, France (EARN adress : UBCH000@FRORS31). =============================================================================
BIORELAY@BIO.CAM.AC.UK (03/20/88)
From: BIORELAY@BIO.CAM.AC.UK From: BIBB@UK.AC.AFRC.JII To: SEQNET@UK.AC.CAM.PHX FOR INCLUSION IN THE NETWORK ADDRESS LIST OF MOLECULAR BIOLOGISTS: NAME: MERVYN BIBB ADDRESS: JOHN INNES INSTITUTE AND AFRC INSTITUTE OF PLANT SCIENCE RESEARCH COLNEY LANE CITY: NORWICH NR4 7UH COUNTY: NORFOLK COUNTRY: ENGLAND PHONE: 44 (0)603 52571 TELEX: 975122 (JIINOR G) TELEFAX: 44 (0)603 56844 NETWORK IDS: USER NAME: BIBB ADDRESS: UK.AC.AFRC.JII PROFESSION: MICROBIAL GENETICIST/MOLECULAR BIOLOGIST CAREER: MOLECULAR GENETICS OF STREPTOMYCES RNA POLYMERASE AND SIGMA FACTOR HETEROGENEITY REGULATION OF GENE EXPRESSION REGULATION OF ANTIBIOTIC BIOSYNTHESIS
BIORELAY@BIO.CAM.AC.UK (03/25/88)
From: BIORELAY@BIO.CAM.AC.UK From: "DANA M. FOWLKES" <DMF@EARN.UNCVAX1> 24-MAR-1988 20:46 To: SEQNET Subj: Seqnet bulletins Via: UK.AC.RL.EARN; Thu, 24 Mar 88 20:45:25 GMT Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 5534; Thu, 24 Mar 88 20:45:25 GM X-Delivery-Notice: SMTP MAIL FROM does not correspond to sender. Received: from UNCVAX1.BITNET (smtpuser) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 5530; Thu, 24 Mar 88 20:45:24 G Date: Thu, 24 Mar 88 14:10 EST From: "DANA M. FOWLKES" <DMF@EARN.UNCVAX1> Subject: Seqnet bulletins To: seqnet@UK.AC.CAM.BIO X-VMS-To: IN%"seqnet@bio.cam.ac.uk" Hi, We have just set up a VAX to handle software, databases and communications for Molecular Biologists, Molecular Geneticists and Biotechnologists. We get bulletins form Biotech server, but I would like to subscribe directly to you bulletins if that is possilbe. We would then re-distribute them to the Univ. of North Carolina local interest groups. Please let me know if this is possilbe. Sincerely yours, Dana M. Fowlkes CB#7525 Univ. of North Carolina at Chapel Hill Chapel Hill, NC 27599-7625 dmf@uncvax1.bitnet =========================================================================== Reply: Dana, To avoid unnecessary transatlantic traffic there is a reciprocal relationship with BIONET. SEQNET distributes BIONET bulletins in Europe and BIONET distributes SEQNET bulletins in North America. I have forwarded to request to Dave Kristofferson at BIONET. Yours, Martin Bishop.
BIORELAY@BIO.CAM.AC.UK (03/28/88)
From: BIORELAY@BIO.CAM.AC.UK From: Julie_Glanville @ UK.AC.NEWCASTLE 25-MAR-1988 15:53 To: SEQNET Subj: Protein synthesis expert systems Date: Fri, 25 Mar 88 15:52:43 GMT From: Julie_Glanville @ UK.AC.NEWCASTLE To: seqnet @ UK.AC.CAM.BIO Subject: Protein synthesis expert systems I am trying to find out what expert systems are available in the field of protein synthesis. I would be grateful for any information. Thanks Julie Glanville Microbiology Dept., University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK email: mma4@uk.ac.ncl.mts
BIORELAY@BIO.CAM.AC.UK (03/31/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: SEQNET@UK.AC.CAM.PHX 31-MAR-1988 09:19 To: BIORELAY Subj: Date: Thu, 31 Mar 88 09:18:30 BST From: SEQNET@UK.AC.CAM.PHX To: biorelay@UK.AC.CAM.BIO Message-ID: <9E4C0E48212A6000@UK.AC.CAM.PHX> (Message number 7) [ u ] Accepted: 09:16:56 31 Mar 88 Submitted: 19:41:00 25 Mar 88 IPMessageId: -unspecified- From: ECOLEEB@EARN.FINFUN To: seqnet@UK.AC.CAM.PHX Subject: Bio-Matrix subscription Via: UK.AC.RL.EARN; Fri, 25 Mar 88 17:40:15 GMT Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 1979; Fri, 25 Mar 88 17:40:15 GM Received: from FINFUN.BITNET (ECOLEEB) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 1977; Fri, 25 Mar 88 17:40:15 X-Original-To: janet%"seqnet@phx.cam.ac.uk", ECOLEEB I'll subscribe the BIO-MATRIX ============== (Message number 14) [ u ] Accepted: 09:17:01 31 Mar 88 Submitted: 11:48:00 30 Mar 88 IPMessageId: -unspecified- From: PFEIFFER@EARN.DM0MPB51 To: SEQNET@UK.AC.CAMBRIDGE.PHOENIX Subject: Position available for system manager/ programmer Via: UK.AC.RL.EARN; Wed, 30 Mar 88 10:50:44 BST Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 7987; Wed, 30 Mar 88 10:50:44 BS Received: from DM0MPB51.BITNET (PFEIFFER) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 7918; Wed, 30 Mar 88 10:50:12 X-Original-To: g--seqnet,mewes, PFEIFFER **************************************************************************** 30-MAR-1988 Position available: The MIPS (Martinsried Institute for Protein Sequence Data) has an open position for a system manager/programmer. We collect and process protein sequence data in a tight cooperation with PIR at NBRF in Washington and JIPID in Japan. Our current system is a local area VAX cluster with a MicroVAX II and a number of workstations. This system will be extended. VAX/VMS experience is required. Applicants should have a sound knowledge of system management and network software (EARN, X25, PSI) to establish on-line services. Knowledge of sequence data analysis software (e.g. PIR, UWGCG) is highly desirable. The position is for 4 1/2 years with the possibility of renewal. It is immediatly available. The salary is about 50.000 DM/year (before taxes and insurances). Written applications should be send to MIPS. H.W. Mewes and F. Pfeiffer **************************************************************************** MIPS am Max-Planck-Institut f. Biochemie Am Klopferspitz 18 D-8033 Martinsried bei Muenchen FRG MIPS@dm0mpb51.Bitnet ****************************************************************************
BIORELAY@BIO.CAM.AC.UK (04/05/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: Paul Andrews <CABELL.ANDREWS@arpa.bionet-20> 4-APR-1988 15:50 To: SEQNET Subj: To Douglas Kell/University College,Wales Received: from bionet-20.arpa by NSS.Cs.Ucl.AC.UK via Satnet with SMTP id aa04748; 4 Apr 88 15:45 BST Date: Mon 4 Apr 88 07:35:54-PDT From: Paul Andrews <CABELL.ANDREWS@arpa.bionet-20> Subject: To Douglas Kell/University College,Wales To: seqnet@arpa.bionet-20 Message-ID: <12387774172.15.CABELL.ANDREWS@BIONET-20.ARPA> Douglas Kell:re-FAD synthesis with C. kluyveri Sorry I have been so long in replying, but I have been out of town for a while and haven't had a chance to check my mail. To remind you of my problem.....I am interested in synthesizing 2-C14-FAD from 2-C14-ribolflavin. One published procedure is to incubate Clostridium kluyveri with C14-riboflavina suggestions from other groups and apparently the approach used now is to produce an "FAD synthetase" complex from Brevibacterium ammoniagenes. I am going to try this approach first before attempting to grow more bacteria. anyway, if I have anymore trouble I may be in touch. Thankyou for your responce. Yours truly (..et merci from a displaced Canadian...) Paul Andrews College of Pharmacy/Medicinal Chemistry University of Texas at Austin Austin, Texas 78712 (EMAIL CABELL.ANDREWS) -------
BIORELAY@BIO.CAM.AC.UK (04/05/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: SEQNET@UK.AC.CAM.PHX 5-APR-1988 11:32 To: SEQNET Subj: Date: Tue, 05 Apr 88 11:31:59 BST From: SEQNET@UK.AC.CAM.PHX To: seqnet@UK.AC.CAM.BIO Message-ID: <9E527571CB3E3A50@UK.AC.CAM.PHX> (Message number 2) Accepted: 11:30:37 05 Apr 88 Submitted: 18:24:00 31 Mar 88 IPMessageId: -unspecified- From: PFEIFFER@EARN.DM0MPB51 To: SEQNET@UK.AC.CAMBRIDGE.PHOENIX Subject: restriction enzyme database Via: UK.AC.RL.EARN; Thu, 31 Mar 88 17:27:54 BST Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 8722; Thu, 31 Mar 88 17:27:54 BS Received: from DM0MPB51.BITNET (PFEIFFER) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 8721; Thu, 31 Mar 88 17:27:53 X-Original-To: g--seqnet, g--george, g--roberts, mewes, PFEIFFER 30-MAR-1988 Dear Rich Roberts! I am sorry that my restriction enzyme lists were announced in Bionet as better than yours. This has never been my intention. Clearly, I myself do not intensely collect information on restriction enzymes, but try to combine yours and Kesslers data with some generally available information (publications and enzyme catalogues) and make them available to users of the PIR and UWGCG package. Thus, my lists are secondary information and cannot be proposed as a substitute for the primary data collection. A separate notice of this will be sent to Seqnet and thus will be distributed through Bionet. I hope that this makes things clear between us and for the scientific community. As David George pointed out, many secondary distributors step in to fill a perceived need. This is exactly what happened to me. Here in Martinsried, we use the PIR and UWGCG software and detected that the enzyme lists were inadequate. Thus, I prepared a local update and made it available to the scientific community so that other scientists do not need to do the same. I do not see a reason why you cannot prepare the restriction enzyme list in the format required by the PIR and UWGCG software yourself. Your database output is very flexible as you say. Please look at their format, prepare the output and send it to both groups. If you do, there is no need for me to continue with my redistribution of data. To my knowledge, you did not offer this in the past. David made a strong point for a standardized format also for your restriction enzyme database. You will remember that I made a similar proposal some time ago. Let me explain why I still feel this to be a necessary topic. It is our historical bad experience With the sequence databases. PIR and UWGCG had inconsistent formats some years ago (luckily solved by now). At that time, the sequence databases were distributed together with the software. Due to this, different database releases were accessed by the different software packages. This situation was very confusing and unsatisfactory. Therefore we decided to get a copy directly from the primary database and to reformat it locally. If you would prepare the restriction enzyme files in the different formats yourself, we would run into the same problem again. Therefore, it seems better to have an updated release of your database in a standard format locally, and to have software for transformation. This software would be specific to the software package and could be distributed with it. Thus each institute could generate the required lists locally and have the same enzymes available for all their program packages. As you can see, the lack of standards causes a lot of confusion. I wonder why Bionet is still not using the IUPAC nomenclature for ambiguous nucleotide symbols. This standard is now several years old and should definitively be adopted by all sequence analysis software packages. Lack of standardization, especially concerning data format, is a severe problem in all existing biological databases. As David pointed out already, the PIR, MIPS and JIPID protein sequence databases try to avoid this problem by close cooperation. During the last months, I could not get hold of your lists from yourself, but received more or less updated versions floating around. Thus, EMBL still seems to distribute a list from beginning of 1987. I recieved the list you recently sent to Kessler at Boehringer, which seems to be a very recent version, only a few days ago. I have not yet managed to compare the data and to update my lists. How far are you with the Oracle database system? We are still in the process of implementation, because my major task is to participate in the organization of the MIPS protein sequence database, and restriction enzymes are only a minor activity. It would be nice, if you and Kessler could agree on a format for data exchange, so that comparison of the data by computer becomes possible. You stated that Kessler's data are not reliable and incomplete. How much do you collect data on methylases and on sensitivity to methylation of restriction enzymes. This is a major point in Kesslers lists. His system discriminates between inhibitory, tolerated, required and undocumented for RE. He also discriminated between different types of modification (pos 4 and 5 of cytosine are currently known, but probably more types of modifiaction will be detected in the future). I am completely confused with your abbreviations of commercial companies. The enzyme list received via Kessler has L = PL-Pharmacia-LKB and P = Promega, while the list received today via David George has P = Pharmacia P-L and R = Promega. My intention is to use the same abbreviation as you, but this is difficult if you are inconsistent with yourself. After talking to Kessler, I have adopted the abbreviations you sent to him, and have extended this list as necessary. Here is my current version. Please comment if you want any changes. Which of your abbreviations will be used in the future? Source Abbreviations A = Amersham B = BRL C = Cambridge Biotechnology Laboratories D = Biores (NL) E = Stratagene (European distributor is Genofit) F = Genofit G = Anglian Biotechnology I = International Biotechnologies Inc K = Takara L = PL-Pharmacia-LKB M = Boehringer Mannheim N = New England Biolabs O = Toyobo (USB in USA, Medac in FRG) P = Promega Biotec R = Brisco (does this exist any longer?) S = Sigma T = Atomergic Chemetals U = USB (see O = Toyobo) V = Serva W = Worthington X = New York Biolabs Y = Chemical Dynamics I am sorry that my lists caused confusion and hope that this letter and the note in Seqnet/Bionet will settle things. Friedhelm Pfeiffer
BIORELAY@BIO.CAM.AC.UK (04/11/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: Deba Patnaik <DEBA@EARN.UMDC> 10-APR-1988 14:34 To: SEQNET Subj: First International Symposium on Marine Molecular Biology Via: UK.AC.RL.EARN; Sun, 10 Apr 88 14:34:22 BST Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 1537; Sun, 10 Apr 88 14:34:22 BS Received: from UMDC.BITNET by UKACRL.BITNET (Mailer X1.25) with BSMTP id 1535; Sun, 10 Apr 88 14:34:21 B Received: by UMDC (Mailer X1.23b) id 5792; Sun, 10 Apr 88 09:33:07 EDT Date: Sun, 10 Apr 88 09:31:46 EDT From: Deba Patnaik <DEBA@EARN.UMDC> Subject: First International Symposium on Marine Molecular Biology To: seqnet@UK.AC.CAM.BIO FIRST INTERNATIONAL SYMPOSIUM ON MARINE MOLECULAR BIOLOGY October 9-11, 1988 Baltimore, Maryland Sponsored by: Office of Naval Research Center of Marine Biotechnology, University of Maryland and National Aquarium in Baltimore The symposium will provide a forum for discussion and exchange of ideas regarding molecular biology and its impact on the marine sciences. _____________________________________________ PROGRAM _______________________________ Sunday, October 9 (at National Aquarium) 5:30-7:00 PM REGISTRATION 6:30 RECEPTION 8:00 WELCOMING 8:30 KEYNOTE ADDRESS Dr. James Ebert, Director Chesapeake Bay Institute, The Johns Hopkins University _____________________________________________ Monday, October 10 Morning Session (at Baltimore Marriott Inner Harbor) Convenor: Dr. Volker A. Erdmann Freie Universitat Berlin 8:15 AM Introductory Remarks 8:30-9:15 Dr. Erko S. Stackebrandt, Institut fur Allgemeine Mikrobiologie der Universitat Kiel, Federal Republic of Germany 9:15-10:00 Dr. Michael J. Silverman, Agouron Institute of Technology 10:00-10:15 BREAK 10:15-11:00 Dr. J. Woodland Hastings, Harvard University 11:00-11:45 Dr. Norman Pace, Indiana University 11:45-12:00 DISCUSSION 12:00-1:30 LUNCH Afternoon Session Convenor: Dr. Fred L. Singleton Center of Marine Biotechnology 1:30-2:15 Dr. Yuzuru Shimizu, University of Rhode Island 2:15-3:00 Dr. Kazuhiro Kogure, University of Tokyo, Japan 3:00-3:20 DISCUSSION 3:20-3:35 CONCLUDING REMARKS Dr. Saul Roseman, The Johns Hopkins University and Center of Marine Biotechnology 3:35-6:00 POSTER SESSION 6:00-9:00 BANQUET _____________________________________________ Tuesday, October 11 Morning Session (at Baltimore Marriott Inner Harbor) Convenor: Dr. Dennis Powers, The Johns Hopkins University and Center of Marine Biotechnology 8:15 AM Introductory Remarks 8:30-9:15 Dr. Igor Dawid, National Institute of Health 9:15-10:00 Dr. Hiroshi Kawauchi, Kitasato University, Japan 10:00-10:15 BREAK 10:15-11:00 Dr. C.L. Hew, University of Toronto, Canada 11:00-11:45 Dr. Yonathan Zohar Hebrew University of Jerusalem, Israel 11:45-12:00 DISCUSSION 12:00-1:30 LUNCH Afternoon Session Convenor: Dr. Allen R. Place Center of Marine Biotechnology 1:30-2:15 Dr. Daniel Morse, University of California at Santa Barbara 2:15-2:45 Dr. Shin-Nan Chen, National Taiwan University, Republic of China 2:45-3:15 Dr. Jo-Ann Leong, Oregon State University 3:15-3:30 DISCUSSION 3:30-3:45 CONCLUDING REMARKS Dr. Thomas T. Chen, Center of Marine Biotechnology 3:45-4:00 FUTURE PERSPECTIVE - Dr. Rita Colwell, Maryland Biotechnology Institute, University of Maryland 4:00-6:00 POSTER SESSION _____________________________________________ FIRST INTERNATIONATIONAL SYMPOSIUM ON MARINE MOLECULAR BIOLOGY October 9-11, 1988 Center of Marine Biotechnology University of Maryland 600 East Lombard St. Baltimore, Maryland 21202 (301) 783-4800 Registration Fees (covers Meetings and Banquet): Regular: $100.00 Student: $25.00 For a registartion packet, please e-mail your US postal address to FISMBB@UMDC.BITNET or FISMBB@UMDC.UMD.EDU OR Call or Write to The Center of Marine Biotechnology, Attn: Greta Dellinger
BIORELAY@BIO.CAM.AC.UK (04/13/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: <SB06@UK.AC.LIVERPOOL.IBM> 11-APR-1988 10:36 To: SEQNET Subj: pc screen to mac Received: from SB06@UK.AC.LIVERPOOL.IBM by ISMAIL(2.1.11); 11 Apr 1988 10:36:50 BST Date: Mon, 11 Apr 88 10:33:14 BST From: <SB06@UK.AC.LIVERPOOL.IBM> Subject: pc screen to mac To: <SEQNET@CAM.BIO> I'm looking for software that can capture an EGA screen in a file format that can subsequently be massaged into a bit-mapped image for printing in a Macintosh system - as a 'paint' type file, on the laserwriter. Has anyone come across such software. The file trasnfer is no problem as we use a TOPS network - its the initial capture/file conversion that is causing problems. Thanks, Rob Beynon Department of Biochemistry University of Liverpool PO Box 147 LIVERPOOL L69 3BX, U.K. SB06@UK.AC.LIV.IBM Dear Dr. Bishop, I would like to participate at your list of molecular biologists in europe. Name: Christoph Heller E-Mail: Bipohl2 at Dknkurz1 Postal address: Fakultaet fuer Biologie Universitaet Konstanz P.O.Box 5560 7750 Konstanz W-Germany Interests: DNA Sequencing, Genome Mapping Technical developments, Computing I would like to register to use the SEQNET bulletin board. VINCENT_MULHOLLAND@UK.AC.NCL.MTS (E-Mail Address) Vincent Mulholland, Department of Genetics, Catherine Cookson Building, University of Newcastle-upon-Tyne, Framlington Place, Newcastle-upon-Tyne, NE2 4HH. (091-2328511 Ext. 3954) RESEARCH: Bacterial plasmid replication and recombination OTHER INTERESTS:Prokayoric gene expression: Restriction/Modification systems
BIORELAY@BIO.CAM.AC.UK (05/25/88)
From: BIORELAY@BIO.CAM.AC.UK From: SEQNET@UK.AC.CAM.PHX 24-MAY-1988 11:16 To: SEQNET Subj: Date: Tue, 24 May 88 11:15:05 BST From: SEQNET@UK.AC.CAM.PHX To: seqnet@UK.AC.CAM.BIO Message-ID: <9E900D0A61660C30@UK.AC.CAM.PHX> (Message number 2) Accepted: 11:13:07 24 May 88 Submitted: 16:16:20 21 May 88 IPMessageId: 9E8C8AC803CD4E90 From: MA11 To: seqnet Drosophila Codon Table Version 4.0 Michael Ashburner, Department of Genetics, University of Cambridge, Cambridge, England. Telephone 44-(0)223-333969 Electronic mail:ma11@uk.ac.cam.phx May 18 1988 These Tables are supplied with the understanding that they can be freely used for research, although if quoted in any publication a suitable acknowledgement (e.g. Michael Ashburner, personal communication) would be appreciated. I will automatically post new versions on the SEQNET and BIONET Bulletin Boards. These will generally be compiled whenever enough new data warrents the work. I am very happy to include new sequences that have not yet made the Sequence Data Banks, if these can be sent to me by electronic mail with sufficient data for the coding sequences to be extracted. If anyone should need the files of coding sequences that have been used to generate these tables please send me a message. Two series of Tables are included, one for "host" genes and one for orfs carried by transposable elements. For each series you have a codon table, a base composition and the names of the sequences used to compile these. By and large these sequences are taken from the EMBL, GENBANK or DAYHOFF Libraries. However some have been privately communicated to me. All sequences have been checked that they translate but many are incomplete. Hence, for example, the number of sequences is greater than the number of TER codons. The latest versions of the databanks used are EMBL V15.0 and GENBANK V55.0. // Table 1A: Codons of "host" genes: TTT 477 TCT 341 TAT 521 TGT 323 TTC 1270 TCC 1071 TAC 1187 TGC 899 TTA 147 TCA 291 TAA 61 TGA 18 TTG 687 TCG 831 TAG 28 TGG 560 CTT 362 CCT 371 CAT 521 CGT 552 CTC 605 CCC 1201 CAC 910 CGC 927 CTA 298 CCA 631 CAA 598 CGA 344 CTG 1986 CCG 814 CAG 1877 CGG 316 ATT 787 ACT 437 AAT 912 AGT 404 ATC 1417 ACC 1418 AAC 1442 AGC 909 ATA 282 ACA 399 AAA 593 AGA 209 ATG 1304 ACG 672 AAG 2304 AGG 259 GTT 577 GCT 864 GAT 1414 GGT 1034 GTC 897 GCC 2164 GAC 1333 GGC 1805 GTA 226 GCA 522 GAA 770 GGA 1233 GTG 1527 GCG 660 GAG 2491 GGG 205 Total = 52495 // Table 1A in Staden format: =========================================== F TTT 477. S TCT 341. Y TAT 521. C TGT 323. F TTC1270. S TCC1071. Y TAC1187. C TGC 899. L TTA 147. S TCA 291. * TAA 61. * TGA 18. L TTG 687. S TCG 831. * TAG 28. W TGG 560. =========================================== L CTT 362. P CCT 371. H CAT 521. R CGT 552. L CTC 605. P CCC1201. H CAC 910. R CGC 927. L CTA 298. P CCA 631. Q CAA 598. R CGA 344. L CTG1986. P CCG 814. Q CAG1877. R CGG 316. =========================================== I ATT 787. T ACT 437. N AAT 912. S AGT 404. I ATC1417. T ACC1418. N AAC1442. S AGC 909. I ATA 282. T ACA 399. K AAA 593. R AGA 209. M ATG1304. T ACG 672. K AAG2304. R AGG 259. =========================================== V GTT 577. A GCT 864. D GAT1414. G GGT1034. V GTC 897. A GCC2164. D GAC1333. G GGC1805. V GTA 226. A GCA 522. E GAA 770. G GGA1233. V GTG1527. A GCG 660. E GAG2491. G GGG 205. =========================================== TOTAL CODONS= 52495. // Table 1B: Base composition of "host" genes: T = 31458 C = 44456 Y = 0 Pyrimidine = 75914 A = 37333 G = 44242 R = 0 Purine = 81575 N = 8 Nucleotides = 157497 // Table 1C: "Host" gene sequences used for Tables 1A and 1B The numbers after the names indicate the number of codons (excluding ter but including N-terminal met); if this number if bracketed then the coding sequence is incomplete. [EMBL/GENBANK Acession numbers] M14643; alpha-tubulin-1, 450 M14644; alpha-tubulin-2, 449 M14645; alpha-tubulin-3, 450 M14646; alpha-tubulin-4, 462 M16922; beta-tubulin-2, 446 M16922; beta-tubulin-3, 448 X05893; acetyl cholinesterase, 649 X06384;Y00212; actin 5C, [137] K00670;K00671; actin 42A, [308] J01064; actin 79B, 376 K00674;K00675; actin 87E, [93] J01065; actin 88F, 376 Z00030; alcohol dehydrogenase, 256 Z00030; 3' orf to Adh, [145] X04695; a-methyl-dopa resistant (amd), 510 X04569; amylase-1, 494 X03788-X03791; Antp, 378 M14549; bicoid, [71] X04896; bsg25D, 741 M14131; C1A9 nuclear protein, 161 K01042; c-ash, [275] X05939; c-myb (13E), 697 K01960; c-ras1 (85D), 189 M10759;M10803;M10804; c-ras2 (64B), 195 X02200; c-ras3 (62B), 182 M11917; c-src (64B), 552 M16599; c-src4 (28C), 590 Y00133; calmodulin, [128] M16534;J03452; casein-hydrolase-alpha-chain, 336 M16534;J03452 casein-hydrolase-beta-chain, 215 X03062; caudal, [197] M13219; choline acetyl transferase, [728] X02947; chorion gene s15-1, 115 X02497; chorion gene s18-1, 272 X02947; chorion gene s19-1, 373 X05245; chorion gene s36, 286 X05245; chorion gene s38, 306 V00200; collagen-like gene fragments, [589] J02727; collagen-IV, [711] X05144; crumbs (EGF-like at 95F), [293] X01761; cytochrome c gene DC3, 105 X01760; cytochrome c gene DC4, 108 X05136; Deformed, 590 X05140; Delta, [200] X04426; dopa decarboxylase, 511 M14978-14982; dunce, 362 X04521; eip28/29, 255 X04024; eip40, 393 M11744; elongation factor (48D), 463 M10017; engrailed, 552 M15961; esterase-6, 548 X05138; even-skipped, 376 X00854;K01951; fushi tarazu, 413 M11254; Gapdh-1, 332 M11255; Gapdh-2, 332 J02527;K02461; glycinimide ribotide transformylase (GART), 1353 M13786; Gpdh [exon 3], [40] J01085; heat shock cognate 70C [exon 1], [68] K01296;K01297; heat shock cognate 87D [exons 1 & 2], [70] J02569; heat shock cognate 88E, [104] X04073; Histone H1, 256 Dayhoff; Histone H2A, [122] Dayhoff; Histone H2B, [118] Dayhoff; Histone H3, [122] Dayhoff; Histone H4, [72] V00209; hsp22, 174 V00210; hsp23, 186 V00211; hsp26, 208 V00212; hsp27, 213 V00213;V00214; hsp70 [87A], [347] J01104;J01105; hsp70 [87C], 641 X03810; hsp82, 717 Y00274; hunchback, 757 M13568; Insulin-like receptor protein-1, [1095] M14778; Insulin-like receptor protein-2, [300] X05273; invected, 576 X03414; Kruppel, 466 X04227; l(2)37Cc, 326 X05426; lethal(2)giant larva, 1160 V00202; larval cuticle protein-1 [44D], 130 V00203; larval cuticle protein-2 [44D], 126 V00203; larval cuticile protein-3 [44D], 112 V00204; larval visceral protein-D [44D], 508 V00204; larval visceral protein-H [44D], 522 V00204; larval visceral protein-L [44D], 505 X03872; LSP1-alpha, [70] X03873; LSP1-beta, [100] X03874; LSP1-gamma, [105] X03758; metallothionein (Mtn), 40 Y00831; mst(3)gl-9 sperm protein, 56 J02788; myosin-heavy chain, 269 M10125; myosin-light chain, 155 X04016; nicotinic acetylcholine receptor (AChR), 521 M11664; Notch, 2703 Y00043; ospsin R7 specific, 383 K02315; opsin, ninaE, 373 M12896; opsin at 91D, 373 M15762; pen#9b, 365 M11969; period, 1127 Y00402; Phosphoenolpyruvate carboxykinase, 647 M14548; paired, 613 X05076;Y00042; protein kinase C, 639 J02527;K02461; pupal cuticle protein (Gart), 184 X05016; ribosomal protein rpA1, 113 X00848; ribosomal protein rp49, 133 X05709; RNA polymerase II-140, 1123 M11798; RNA polymerase II-215, [470] Y00308; rosy, 1335 X04813; rudimentary, 2356 X01918; Sgs3, 307 J01135;J01136; Sgs4, [141] X04269; Sgs5, 163 X01918; Sgs7, 74 X01918; Sgs8, 75 Y00288; snail, 390 X04513; snake, 430 X03121; serendipity-alpha, 530 X03121; serendipity-beta, 351 X03121; serendipity-delta, 430 Y00367; superoxide dismutase, 213 K03277; tropomyosin I, T-isoform, [198] M15466; tropomyosin II, 285 X02989; trypsin-like enzyme, alpha-chain, 256 X05723;Y00206; Ubx, 389 X01802; vitelline membrane protein, [96] X02974; white, 541 Chia; yellow, 696 V00248; yolk protein-1, 459 J01157; yolk protein-2, 459 M15898; yolk protein-3, 420 Y00049; zeste, 575 // Table 2A: Codon table TE genes: TTT 366 TCT 129 TAT 264 TGT 108 TTC 200 TCC 120 TAC 230 TGC 107 TTA 351 TCA 197 TAA 1 TGA 1 TTG 195 TCG 74 TAG 0 TGG 108 CTT 216 CCT 112 CAT 187 CGT 64 CTC 104 CCC 104 CAC 165 CGC 38 CTA 199 CCA 271 CAA 396 CGA 99 CTG 105 CCG 52 CAG 160 CGG 22 ATT 463 ACT 205 AAT 620 AGT 180 ATC 175 ACC 171 AAC 403 AGC 145 ATA 447 ACA 374 AAA 888 AGA 260 ATG 199 ACG 64 AAG 282 AGG 83 GTT 181 GCT 160 GAT 330 GGT 130 GTC 106 GCC 129 GAC 305 GGC 107 GTA 188 GCA 222 GAA 566 GGA 148 GTG 113 GCG 63 GAG 227 GGG 39 Total = 12718 // Table 2A in Staden format: =========================================== F TTT 366. S TCT 129. Y TAT 264. C TGT 108. F TTC 200. S TCC 120. Y TAC 230. C TGC 107. L TTA 351. S TCA 197. * TAA 1. * TGA 1. L TTG 195. S TCG 74. * TAG 0. W TGG 108. =========================================== L CTT 216. P CCT 112. H CAT 187. R CGT 64. L CTC 104. P CCC 104. H CAC 165. R CGC 38. L CTA 199. P CCA 271. Q CAA 396. R CGA 99. L CTG 105. P CCG 52. Q CAG 160. R CGG 22. =========================================== I ATT 463. T ACT 205. N AAT 620. S AGT 180. I ATC 175. T ACC 171. N AAC 403. S AGC 145. I ATA 447. T ACA 374. K AAA 888. R AGA 260. M ATG 199. T ACG 64. K AAG 282. R AGG 83. =========================================== V GTT 181. A GCT 160. D GAT 330. G GGT 130. V GTC 106. A GCC 129. D GAC 305. G GGC 107. V GTA 188. A GCA 222. E GAA 566. G GGA 148. V GTG 113. A GCG 63. E GAG 227. G GGG 39. =========================================== TOTAL CODONS= 12718. // Table 2B: Base composition TE genes: T = 9774 C = 7350 Y = 0 Pyrimidine = 17124 A = 14591 G = 6439 R = 0 Purine = 21030 N = 0 Nucleotides = 38154 // Table 2C: TE genes used for Tables 2A and 2B: [EMBL/GENBANK Accession numbers] X01472; 17.6 element X03431; 297 element X04132;X03733; 412 element X02599; copia element [Saigo] V00246; FB4 X03734; gypsy element X01748; HB1 X04705; hobo Finnegan I element O'Hare; P element X01747; transposon HB2 X02600; virus like particle RNA (VLP H-RNA) //
BIORELAY@BIO.CAM.AC.UK (05/25/88)
From: BIORELAY@BIO.CAM.AC.UK From: MJB1@UK.AC.CAM.PHX 24-MAY-1988 13:18 To: BIORELAY Subj: Date: Tue, 24 May 88 13:17:30 BST From: MJB1@UK.AC.CAM.PHX To: biorelay@UK.AC.CAM.BIO Message-ID: <9E9028674E0E0A00@UK.AC.CAM.PHX> THE BRITISH LIBRARY BIOTECHNOLOGY INFORMATION NEWS NO. 16, MARCH 1988 ISSN 0952-147X _____________________________________________________________________________ Biotechnology Information News is published 4 times year, free of charge, by the British Library Biotechnology Information Service, 25 Southampton Buildings, London WC2A 1AW, UK (telephone 01 323 7293). _____________________________________________________________________________ IN THIS ISSUE ____________________________________________________ The new Biotechnology Information Service newsletter ____________________________________________________ Microbial Culture Information Service ____________________________________________________ Microbial Information Network Europe ____________________________________________________ Biotech Knowledge Sources ____________________________________________________ Document Supply Centre ____________________________________________________ New companies ____________________________________________________ Seminar on biotechnology information ____________________________________________________ THE NEW BIOTECHNOLOGY INFORMATION SERVICE NEWSLETTER Welcome to Biotechnology Information News, the successor to EBIP News. The new title reflects our transformation from EBIP to the Biotechnology Information Service, now fully funded by the British Library. The aim of the Newsletter is to give readers news about the Biotechnology Information Service, and the British Library in general, and also to cover biotechnology in the wider world - industry, science and information systems. We welcome contributions from readers, whether to comment on past articles or to raise new issues. The Biotechnology Information Service is presently concentrating its energies in three areas: a help desk, publications and courses. We will attempt to answer any biotechnology queries, using the vast collection at the Science Reference and Information Service. We have special knowledge of this field and the people who work in it and we can usually supply information or suggest suitable resources to deal with a particular problem. Our number is 01 323 7293. Biotech Knowledge Sources (BKS) is a major new publication which in- corporates, and extends, our earlier publications, Market Research Reports and Forthcoming Conferences and Courses. See below for more details. The Biotechnology Information Service holds a regular seminar giving a general introduction to biotechnology information. The latest, held on 26 January, was well attended and we are grateful to delegates for the feedback they provided through the evaluation forms. This informa- tion will be very useful for shaping future seminars. The next seminar is on 7 July and further details can be found below. Another seminar will be held on 24 November. We are also considering ways of expanding our seminar programme, possibly by introducing a new seminar devoted to a specialist area within biotechnology, such as business information. Details of new developments will be announced in Biotechnology In- formation News. _____________________________________________________________________________ ***************************************************************************** MICROBIAL DATA SYSTEMS A. Microbial Culture Information Service (MiCIS) The Microbial Culture Information Service (MiCIS) is a project funded by the Department of Trade and Industry. It is part of the Biotechnology Research Group at the Laboratory of the Government Chemist (LGC). We originally reported on the early stages of the project (EBIP News No. 13, March 1987) when Geraldine Alliston was in charge. Mrs Alliston has now moved on, and her successor will arrive shortly. Most of the data has now been loaded including records from the following collections: National Collection of Type Cultures, National Collection of Pathogenic Fungi, National Collection of Industrial Bacteria, National Collection of Marine Bacteria, National Collection of Food Bacteria, National Collection of Yeast Cultures and CAB International Mycological Institute collection. The latter two collec- tions were added by direct conversion of existing computer records. Still awaiting keyboarding are the Culture Collection for Algae and Protozoa (now in 2 sections, one for marine algae and one for freshwater algae and protozoa) and the National Collection of Wood Rotting Fungi (due to move to the Building Research Establishment site at Garston, Watford in the next year or so). Data is collected by two teams of 2 people each who work at the centres in turn, converting records into a computer format. The records are then loaded into the multiuser relational database manage- ment system running on the mini-computer at the LGC. To facilitate retrieval the index terms are validated and checked against lists of controlled terms covering chemical names and other keywords, and the names of organisms. For an annual subscription of 200 a year the user has online access to the database, a user guide which includes a list of all the preferred terms used in indexing, and customer support services. It is not necessary to have facilities for a computer link-up to search MiCIS. Postal subscribers pay 200 annually and then a flat rate of 10 per search carried out by MiCIS staff. Casual enquiries will also be carried out for non-subscribers a cost of 50 each. For more information contact Jane Bonner, MiCIS Database Administrator, Laboratory of the Government Chemist, Cornwall House, Waterloo Road, London SE1 8XY (Tel: 01 211 0323). B. Update on Microbial Information Network Europe (MINE) by Rhonda Platt, MINE Project Administrator at CAB International Mycological Institute, Ferry Lane, Kew, Surrey TW9 3AF MINE is an Integrated Catalogue Project, incorporating a European Network of Microbial Culture Collection Databanks. This project is funded by the EEC Biotechnology Action Programme and the objective is to establish a computer network of microbial information across Europe. Since the beginning of 1988 two more European countries have joined the project bringing the total to seven European partners; Bel- gium, France, Germany, the Netherlands, Portugal, Spain and the UK. CAB International Mycological Institute is acting as the UK node, and 10 UK collections, including the CMI Culture Collection, are par- ticipating in this node. Keyboarding and computer transfer of collec- tion data is underway on those collections not available on MiCIS. It is hoped that MiCIS data can be directly downloaded to the CAB Inter- national VAX 11/780-8250 computer cluster and avoid duplication of ef- fort. The UK Node may store as much data as the individual collection wishes, but once all data is stored on the VAX, a Minimum Data Set (MDS) only will be transferred to other nodes. Hence, when all nodes have exchanged MDS's, each node will hold on its own computer (VAX or VAX compatible) a European database. People wishing to access the database will therefore contact their local node. If the information required is not within the scope of the MDS, the enquirer will be referred to the holding collection or MiCIS as appropriate. MiCIS will hold full strain data of all UK national culture collections. Although MINE may hold extensive strain data at node level, the eventual European database held at each node will contain the Minimum Data Set only. Those who wish to study the Minimum Data Set will be able to do so in the near future in the Journal of General Microbiology which will be publishing a paper by W.Gams et al, "Fungal and yeast strain data in MINE". A similar paper will be published later for bacteria. The MDS contains 30 fields on: Computer details, Name, Strain details, Status, Environment and History, Biological Interactions, Sexuality, Genotype and Genetics, Growth Conditions and Practical Applications. Full integration of the MDS's of each node should be completed by the end of 1989. _____________________________________________________________________________ ***************************************************************************** BIOTECH KNOWLEDGE SOURCES January saw the launch of Biotech Knowledge Sources (BKS), a new cur- rent awareness journal produced by the British Library Biotechnology Information Service in collaboration with BioCommerce Data Ltd. Over recent years, there has been a marked increase in the number of publi- cations in biotechnology. This is anticipated to continue as biotech- nology grows and impacts on other established industries. Therefore, to save you time, and save your organisation money, this unique serv- ice gives a comprehensive monthly listing of new books, journals and market research reports in the field of of biotechnology. BKS also lists forthcoming conferences up to six months ahead. Every issue con- tains, wherever possible, full address information to enable readers to make further enquiries about publication or conference registration details. There are 12 issues per year. The information is obtained by scanning online databases, publishers' catalogues, journals and press releases. Details of electronic publications and audiovisual material are also included. For a limited period we are offering readers of Biotechnology Infor- mation News the first year's subscription at the special introductory rate of 89. If you would like to place an order or make further en- quiries please contact Dr Anita Crafts-Lighty, BioCommerce Data Ltd, Old Crown Building, Windsor Road, Slough SL1 2DY, UK (Tel: 0753 74201, Fax:0753 31145). _____________________________________________________________________________ DOCUMENT SUPPLY CENTRE The British Library Document Supply Centre is an important resource for libraries throughout the UK and abroad. It holds current subscrip- tions to 54,000 journal titles and its total holdings occupy over 90 miles of shelf space. It routinely turns requests around within 2 days. If that is not fast enough Special Services can retrieve ar- ticles on the spot and send them out the same day, by post or by fax. DSC can also help with current awareness, through its publications and other services. Conference proceedings, for example, often bring together useful contributions but may not be easy to trace. Only 30% are published as books, the remainder appear within journals. All material arriving at DSC is scanned to produce the monthly publication Index of Conference Proceedings Received. Here can be found the full title of a conference, date, location and publication details. The records are indexed by keywords extracted from the title. The monthly issues are cumulated annually and, for the years 1964-81, there is a single cumulation on microfiche. It is a comprehensive guide to con- ferences in its own right, as well as being an index of material at DSC available for loan. Current Research in Britain is published annually by DSC and gives details of research projects at universities, polytechnics and other institutions throughout the UK. The information is organised by re- search centre but there are full indexes to investigators, subject areas and research topics. There are separate volumes on Biological Sciences and Physical Sciences and each lists a large number of entries under the subject area Biotechnology. The latest edition ap- peared in 1987. The Medical Information Service prepares current awareness bulletins based on records compiled for the Medline database. Typical subject areas are Cytodiagnosis, Health Care in Britain and Psychotherapy. There are an increasing number of research theses being written on biotechnology. Much of the data presented in them may not be published elsewhere. DSC microfilms most UK doctoral theses (around 6000 per year) and copies are available for loan. Interesting titles may be found through DSC's monthly publication British Reports, Translations and Theses. This information is also available on the SIGLE database on BLAISE-LINE. For more information on these and other current awareness services, please contact Customer Services, British Library, Document Supply Centre, Boston Spa, Wetherby, W.Yorkshire LS23 7BQ. _____________________________________________________________________________ NEW COMPANIES Bioseparation Associates was launched in February 1988 and is based in Livingstone, Scotland. The company has start-up funds of 3.5 mil- lion, a porportion of which was contributed by Guinness Mahon Development Capital, a venture capital company. It aims to recover useful products from abattoir blood by means of a spe- cial microfilter. At present the two main areas of interest are animal feed supplements and nutrient additives for tissue culture estimated to have a world market in excess of 100 million. Oxford Glycosystems, formed by a collaboration between Oxford University's Biochemistry Department and the giant American drug com- pany, Monsanto will develop and market products for the research and clinical community for use in carbohydrate technology.. The company is expected to have a turnover of 25 million within five years. ______________________________________________________________________________ P.S. Thank you to everybody who returned their reply slips to register as continuing subscribers to Biotechnology Information News _____________________________________________________________________________ ***************************************************************************** SEMINAR ON BIOTECHNOLOGY INFORMATION Information about biotechnology covers many areas, from pure research to product marketing. This one day course will introduce you to biotechnology information in business, industry and science. The talks will be illustrated by numerous examples of books, journals, online services and information centres used by the Biotechnology Information Service. The seminar will be of interest to information workers new to biotechnology, and scientists and managers wishing to learn more about information sources. Topics will include:- - Business information Directories, trade literature, abstracts, online services - Online information Hosts, databases, search strategies - Official publications Role of Government, legislation, reports, books - Scientific information Journals, books, abstracts, directories - Patents Scientific and industrial information, online services - Culture collections and databanks Catalogues, online services Date: 7 July 1988 Fee: 75 plus VAT (86.25 incl. VAT) Location: Science Reference and Information Service, 25 Southampton Buildings, London WC2A 1AW (Please note, another seminar will be held on 24 November 1988 and will be announced in Biotechnology Information News) Applications not later than 2 weeks before Seminar date should be sent to Marketing and Public Relations, British Library, Science Reference and Information Service, 25 Southampton Buildings, London WC2A 1AW (01 323 7471). A letter of confirmation will be sent.
BIORELAY@BIO.CAM.AC.UK (05/29/88)
From: BIORELAY@BIO.CAM.AC.UK From: David Kristofferson <Kristofferson@arpa.bionet-20> 28-MAY-1988 08:29 To: SEQNET Subj: BIOSCI - A NEW INTERNATIONAL BULLETIN BOARD NETWORK! Received: from bionet-20.arpa by NSS.Cs.Ucl.AC.UK via Satnet with SMTP id aa03822; 28 May 88 8:15 BST Date: Fri 27 May 88 23:21:46-PDT From: David Kristofferson <Kristofferson@arpa.bionet-20> Subject: BIOSCI - A NEW INTERNATIONAL BULLETIN BOARD NETWORK! To: BIONET-NEWS@arpa.bionet-20, BIOTECH <BIOTECH%umdc%edu.stanford.forsythe%arpa.bionet-20@uk.ac.ucl.cs.nss> SEQNET@arpa.bionet-20 cc: IG-STAFF@arpa.bionet-20, Kristofferson@arpa.bionet-20 Message-ID: <12401839995.15.KRISTOFFERSON@BIONET-20.ARPA> The following announcement is being posted at the BIONET National Computer Resource for Molecular Biology in California, the University of Maryland BIOTECH bboard service, the University of Uppsala in Sweden, and on the SEQNET service in Cambridge, England. From these initial sites it will be distributed to other institutions around the world. ---------------------------------------------------------------------- The International BIOSCI Electronic Bulletin Board Network __________________________________________________________ A new international molecular biology electronic bulletin board ("bboard") network is being established. The name of this new bboard network will be BIOSCI, and its goal is to allow researchers easy access to scientific bulletin boards at local or regional sites ("nodes") on an accessible network. These nodes will establish a routing system which will automatically forward local bboard messages to the corresponding bboard at all other nodes. Scientists will thus be able to communicate directly with their colleagues around the world without specializing in network esoterica. They will also be able to participate in only the special interest groups (see the initial list below) that they desire to see. Messages to the bboards are posted without editorial intervention. This policy will be maintained until traffic reaches a level at which editorial moderation needs to be established. As the first step in implementing this scheme, the bulletin boards maintained presently by the BIONET National Computer Resource for Molecular Biology in the U.S.A. will be expanded to include the participation of other sites. BIONET's first collaborator in this new venture is the Biomedical Center at the University of Uppsala in Sweden. In the near future BIOTECH at the University of Maryland and SEQNET in the U.K. will also join. From now until July BIOTECH will receive messages from each of the bboards listed below and will archive them under the respective categories in their list server which is accessible to both BITNET and Internet users. After that time BIOTECH will have software in place to both receive and forward separate bboards to other sites. SEQNET in England is also acquiring new hardware for bboard distribution, and the European Molecular Biology Laboratory and the University of Joensuu in Finland have also expressed an interest in participating. Other sites are invited to participate if they possess the necessary hardware and software for multiple bboard distribution (please contact kristofferson@bionet-20.arpa or mats@bmc.BMC1.UU.SE). The current list of bboards follows but other topics will be added as demand requires. Users can post messages to any of the boards below by mailing to the appropriate address at either BIONET or the University of Uppsala (whichever is more convenient). Each bboard address consists of the bboard name from the list below followed by the host name of the University of Uppsala or BIONET computer. For example, the PLANT-MOLECULAR-BIOLOGY bboard can be accessed by mailing to either plant-molecular-biology@bmc1.BMC.UU.SE or plant-molecular-biology@bionet-20.arpa. EARN users can mail to the abbreviated address (<= 8 characters / bboard name) at the University of Uppsala. BBOARD NAME TOPIC ----------- ----- BIONET-NEWS General BIONET announcements BIO-MATRIX Applications of computers to biological databases CONTRIBUTED-SOFTWARE Information on public-domain mol. biol. programs EMBL-DATABANK Messages to and from the EMBL database staff EMPLOYMENT Job opportunities in the biological sciences GENBANK-BB Messages to and from the GenBank database staff GENE-EXPRESSION Scientific Interest Group GENOMIC-ORGANIZATION Scientific Interest Group METHODS-AND-REAGENTS Requests for information and lab reagents MOLECULAR-EVOLUTION Scientific Interest Group ONCOGENES Scientific Interest Group PC-COMMUNICATIONS Information on PC communications software PC-SOFTWARE Information on PC-software for scientists PIR Messages to and from the PIR database staff PLANT-MOLECULAR-BIOLOGY Scientific Interest Group PROTEIN-ANALYSIS Scientific Interest Group RESEARCH-NEWS Research news of interest to the community SCIENCE-RESOURCES Information about funding agencies, etc. YEAST-GENETICS Scientific Interest Group Sample BBoard posting address format: molecular-evolution@bionet-20.arpa molecular-evolution@bmc1.bmc.uu.se (EARN) mol-evol@semax51 The BITNET/EARN abbreviations follow: BBOARD NAME BITNET/EARN Name ----------- ----- BIONET-NEWS BIONETBB BIO-MATRIX BIOMATRX CONTRIBUTED-SOFTWARE SOFT-CON EMBL-DATABANK EMBL-DB EMPLOYMENT BIOJOBS GENBANK-BB GENBANKB GENE-EXPRESSION GENE-EXP GENOMIC-ORGANIZATION GENE-ORG METHODS-AND-REAGENTS METHODS MOLECULAR-EVOLUTION MOL-EVOL ONCOGENES ONCOGENE PC-COMMUNICATIONS SOFT-COM PC-SOFTWARE SOFT-PC PIR PIR-BB PLANT-MOLECULAR-BIOLOGY PLANT PROTEIN-ANALYSIS PROTEINS RESEARCH-NEWS RESEARCH SCIENCE-RESOURCES SCI-RES YEAST-GENETICS YEAST Both the Biomedical Center at University of Uppsala and BIONET now handle requests for additions and deletions from the BIOSCI mailing lists. Send requests (or other administrative matters) to the appropriate BIOSCI address below. The Americas ------------ biosci@bionet-20.arpa Europe ------ Internet address: biosci@bmc1.BMC.UU.SE (preferred) Bitnet address: biosci@semax51 Elsewhere --------- whichever address above is more accessible. Eventually the University of Uppsala will handle redistribution primarily in Scandinavia, but will temporarily handle distribution to other European sites as well until other regional redistribution sites are established. In the United States BIONET and BIOTECH will soon be sharing this responsibility and additional sites may be added. BIOSCI represents a new advance in communications in the biological sciences. We believe that the community will find this endeavor to be both rewarding and exciting! Sincerely, Mats Sundvall David Kristofferson, Ph.D. mats@bmc.BMC1.UU.SE Manager, BIONET Resource kristofferson@bionet-20.arpa ---------------------------------------------------------------------- Technical note to European EARN users: If you are on BITNET you can route RFC822 mail to the .SE domain as described below ------ Domain: .SE Name: SUNET, Swedish University NETwork Gateway: MAILER@SEKTH Gatemaster: POSTMAST@SEKTH Please use this gateway or other Internet routes if you can until other EARN nodes are added to the BIOSCI network. In the U.S. and Canada most BITNET sites can route mail by addressing directly to @bionet-20.arpa addresses. Either the full bboard names or the BITNET abbreviations may be used, e.g., bionet-news@bionet-20.arpa or bionetbb@bionet-20.arpa ------------------------------------------------------------------------- ------- From: MJB1@UK.AC.CAM.PHX 29-MAY-1988 11:47 To: SEQNET Subj: Date: Sun, 29 May 88 11:42:25 BST From: MJB1@UK.AC.CAM.PHX To: seqnet@UK.AC.CAM.BIO Message-ID: <9E965C7C98746440@UK.AC.CAM.PHX> (Message number 15) Accepted: 11:24:16 29 May 88 Submitted: 22:00:00 27 May 88 IPMessageId: <34920@mun.bitnet> From: William H. E. Day <whday@EARN.MUN> To: mjb1@UK.AC.CAMBRIDGE.PHOENIX Subject: E-mail Directory Announcement Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 9787; Sat, 28 May 88 03:05:41 BS Received: from mun.bitnet (WHDAY) by UKACRL.BITNET (Mailer X1.25) with BSMTP id 9782; Sat, 28 May 88 03:05:41 Received: from mun.bitnet by mun.bitnet via DECnet; id M34920; (mailer v1.1 exp/Nov 87); 27 May 88 22:00 -03 From: KEAN::WHDAY "William H. E. Day" 27-MAY-1988 00:38 To: WHDAY,WHDAY Subj: E-mail Directory Researchers in Classification, Clustering, Phylogenetic Reconstruction Or Related Methods of Data Analysis Date: 27 May 1988 Next distribution: 3 June 1988 Listing in this directory is NOT restricted to members of particular societies or to residents of particular countries. The directory usually does not include addresses for sending mail from one network domain to another since such addressing conventions usually depend on the originating node. Please send: suggestions, instructions for insertions, deletions, or changes, or E-mail addresses of persons who might like to be listed to William H. E. Day (WHDAY@MUN). While William H. E. Day, the compiler of this directory, believes the information in it to be true and accurate, he cannot accept any legal responsibility for any errors or omissions that may be made, and he makes no warranty, express or implied, with respect to the material contained herein. Network Domain Name Abbreviation ------------------------------------------------- ------------ ARPANET (Advanced Research Projects Agency)/Internet A BITNET, EARN, NETNORTH B CDNnet (CanaDiaN network) CDN CSNET (Computer Science NETwork) CS JANET (Joint Academic NETwork) J SPAN (Space Physics Analysis Network) S UUCP (Unix to Unix CoPy) U User Name(*New Listing) Domain User Address Within Domain ------------------------ ------ ------------------------------------ Adorf, Hans-Martin* B ADoRF@DGAESo51 Arabie, Phipps B ARABIE@UIUCVMD Arbeitsgruppe 1 B XMATD403@DDATHD21 Berthet, Paul B BoLA@BUCLLN11 Bock, Hans H. B CHABoCK@DACTH01 Bockenholt, Ulf B U612@UIUCVMD Boster, James B BoSTER@PITTVMS Burmeister, Peter B XMATD403@DDATHD21 Carlier, Andre L. B CARLIER@FRToU71 Carr, Steven M. B SCARR@MUN Carroll, J. Douglas A jdc@research.att.com U alice!jdc U research!jdc Concept Analysis Group B XMATD403@DDATHD21 Daws, John T. B JDAWS@UIUCVMD Day, William H. E. B WHDAY@MUN CDN whday@garfield.mun U garfield!whday De Soete, Geert B GEERT@BGERUG51 de Leeuw, Jan A deleeuw@ucla.math.edu B DELEEUW@UCLASSCF DeSarbo, Wayne S. A wsd@research.att.com U alice!wsd Desbois, Dominique B DESBoIS@CIEARN Douglas, Michael E. B ABMED@ASUACAD Dubes, Richard C. CS dubes@cpswh.cps.msu.edu DuBose, Robert F.* B DUBoSE_B@WUMS Ellis, Willem N. B U00267@HASARA5 (until 31/12/1988) B U00267@SARA.NL (after 30/06/1988) Felsenstein, Joseph* A joe@evolution.ms.washington.edu U uw-beaver!uw-entropy!uw-evolution!joe Fitch, Walter M. B WFITCH@USCVM Ganter, Bernhard B XMATD403@DDATHD21 Golding, G. Brian B FS300047@YUSoL Gordon, Allan D. J stsag@uk.ac.st-and.savb from BITNET try... STSAG@SAVB.ST-AND.AC.UK Green, Roger H. B CLAMBo@UWoVAX B RGREEN@UWoVAX Gutman, George A.* B GAGUTMAN@UCI Haedrich, Richard L.* B HAEDRICH@MUN Hartl, Daniel L.* B HARTL_D@WUMS Hirtle, Stephen C. B HIRTLE@PITTVMS U decvax!idis!sch Hubert, Lawrence J.* A l-hubert%uiucpsy@uiucuxc.cso.uiuc.edu A l-hubert%uiucpsy@uxc.cso.uiuc.edu Innes, David J. B DINNES@MUN Kiers, Henk A. L. B KELINCI@HGRRUG5 Kruskal, Joseph B. A jbk@research.att.com U research!jbk Lawrence, Jeffrey G.* B HARTL_D@WUMS Legendre, Pierre B 3771@UMTLVR Ling, Robert F. B RFLING@CLEMSoN McMorris, F. R. B FRMCMo01@ULKYVX Milligan, Glenn W. B TS0914@oHSTVMA Murtagh, Fionn D. B FIM@DGAIPP1S B FIoNN@DGAESo51 S ESoMC1::FIoNN Oden, Neal L. B oDEN@BNLCL1 Rohlf, F. James B RoHLF@SBBIoVM Salemans, Ben J. P. B U216013@HNYKUN11 Shao, Kwang-Tsao* B WN7A1004@TWNMoE10 Sokal, Robert R. B CHERYL@SBBIoVM Swofford, David L.* A daveswof@vmd.cso.uiuc.edu B DAVESWOF@UIUCVMD U uiucuxc!daveswof ten Berge, Jos M. F.* B JOSTENB@HGRRUG5 van Schuur, Wijbrandt H. B WSCHUUR@HGRRUG5 Wareham, H. Todd B HARoLD@MUN CDN harold@garfield.mun U garfield!harold Wartenberg, Daniel B 2248001@RUTVM1 Weinberg, Sharon L. B WEINBERG@NYUACF Wille, Rudolf B XMATD403@DDATHD21 Wilson, George D.F.(Buz)* A gdwilson@ucsd.edu A buz%sdcc12@ucsd.edu A st199gw%sdcc12@ucsd.edu B GDWILSoN@UCSD U ucsd!gdwilson Windham, Michael P. B MWIND@USU Zuker, Michael B ZUKER@NRCVM01 -------------------------------------------------------------------- END OF E-MAIL DIRECTORY Total # of Entries: 57 27 MAY 1988 ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
BIORELAY@BIO.CAM.AC.UK (06/06/88)
From: BIORELAY%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU From: MJB1@UK.AC.CAM.PHX 6-JUN-1988 09:32 To: SEQNET Subj: Date: Mon, 06 Jun 88 09:31:31 BST From: MJB1@UK.AC.CAM.PHX To: seqnet@UK.AC.CAM.BIO Message-ID: <9EA04E19F035BC60@UK.AC.CAM.PHX> (Message number 9) Accepted: 09:26:01 06 Jun 88 Submitted: 15:56:10 01 Jun 88 IPMessageId: -unspecified- From: HAZLEDINE@EARN.EMBL To: mjb1@UK.AC.CAM.PHX Subject: File server announcement for SEQNET Received: from UKACRL by UK.AC.RL.IB (Mailer X1.25) with BSMTP id 5632; Wed, 01 Jun 88 14:57:57 BS Received: from EMBL(HAZLEDIN) by UKACRL (Mailer X1.25) id 5624; Wed, 01 Jun 88 14:57:56 BS Organisation: European Molecular Biology Laboratory Postal-address: Meyerhofstrasse 1, 6900 Heidelberg, W. Germany Phone: +49 (6221) 387-0 [switchboard] Martin, Would you post this announcement about our file server upgrade on SEQNET please. (It's finally accessible from JANET!) Thanks, Dave. // EMBL Network File Server ------------------------ We are pleased to be able to announce a major upgrade to the EMBL file server. The server now accepts STANDARD ELECTRONIC MAIL, sent either over BITNET/EARN or FROM ANY OTHER NETWORK WHICH HAS A GATEWAY INTO BITNET/EARN. This means, to take just two examples, that users in the UK connected to JANET and users in the USA connected to ARPANET can now use the file server. You should send mail to the BITNET/EARN address NETSERV@EMBL; it should be formatted with one file server command per line. The most important command, to get you started, is HELP. If the file server receives this command, it will return a help file to you, explaining in some detail what you can do with the server and how to use it. Please note that the operating system command you use to send mail to a BITNET/EARN address, and the way in which you format the address NETSERV@EMBL, will depend both on the computer you are using and on the network to which it is connected. If you don't already know how to send mail to a BITNET/EARN address, we suggest that you contact your local computer service; if all else fails, contact the Data Library and we will do our best to help. For example, suppose you are using a VAX/VMS system which is a BITNET/EARN node running JNET software. In this case you would use the VMS MAIL command to send mail to the server. If you wanted to send a HELP command, your session on the VAX would look like this (user input in lowercase): $ MAIL MAIL> send To: jnet%"netserv@embl" Subj: help <ctrl/z> If the command you use to send mail allows you to specify a "subject", as in the above example, then please note that anything you specify as the "subject" will be treated as a file server command. Those of you who have already used the server, by sending interactive messages over BITNET/EARN, should note that this access method is still available. However, it offers no advantages over standard electronic mail and we would recommend that you switch to the latter. We would like to emphasise that you can use the file server to download sequences added to the EMBL database since the current release was distributed, in addition to the sequences in the current release itself. We are well aware that the file server is not (yet!) perfect, and are planning several enhancements. The most important ones are to give users direct access to sequences by accession number as well as by entry name, and to make index files available which cover just those sequences added to the database since the current release was distributed. (Such index files would be much smaller than the current ones, which cover all sequences in the database, and would thus be sent much more quickly over computer networks.) We hope to make progress on the question of direct access by accession number in the not too distant future, and would like to draw your attention to the fact that one of the index files (the catalogue of one-line entry descriptions) is already available for new sequences only. The file DATALIB:NEWENTS.TXT contains brief descriptions, entry names and sequence lengths for all those sequences added to the database since the current release was distributed. Like all of the other index files, it is updated daily to include all sequences newly added to the database. If you have any technical problems in accessing the file server then please mail to POSTMASTER@EMBL.EARN. If you have any general comments about the file server (or any other aspect of our services) then please send them to us; we want to tailor our services to meet your requirements, and the more feedback we get the better. We cannot undertake to respond personally to all comments, but you can be sure that we want to know what you think! EMBL Data Library Postfach 10.2209 D-6900 Heidelberg West Germany Telephone : +49-6221-387258 Email (general enquiries): DATALIB@EMBL.EARN Email (data submissions) : DATASUBS@EMBL.EARN From: BIO::BIONET 6-JUN-1988 09:44 To: SEQNET Subj: From: BIO::JCJB 1-JUN-1988 15:12 To: BIONET,JCJB Subj: PLEASE put this in the bulletin for EDL (again). UNIVERSITY OF CAMBRIDGE DEPARTMENT OF BIOCHEMISTRY POSTDOCTORAL RESEARCH ASSOCIATE EUKARYOTIC GENE EXPRESSION/PROTEIN-DNA INTERACTIONS Applications are invited for a three year postdoctoral position funded by the SERC Molecular Recognition Initiative to study yeast gene regulatory proteins. The work will use biochemical/molecular biological and NMR spectroscopic techniques to study the structure and function of these proteins. Applicants with experience in biochemistry/molecular biology would be very welcome, but candidates with other relevant backgrounds are encouraged to apply. The post is available (starting date negotiable) at a starting salary within the range 9,305 -13,675 pounds (according to age and experience). Applicants should apply before 31st June, sending a full C.V. naming two academic referees, to Dr. E.D. Laue, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, U.K., (telephone Cambridge 333677) from whom further details may be obtained. UNIVERSITY OF CAMBRIDGE DEPARTMENT OF BIOCHEMISTRY WITH MEIKO LTD. POSTDOCTORAL RESEARCH ASSOCIATE PARALLEL PROCESSING/PROTEIN STRUCTURE DETERMINATION Applications are invited for a three year postdoctoral position funded jointly by the SERC and Meiko Ltd. to work on the development of software for NMR data processing, including the Maximum Entropy Method (MEM), and protein structure determination. The software will be implemented on a Meiko Computing Surface, a parallel processor based on the Inmos Transputer. The successful applicant will collaborate with workers at Meiko Ltd. in Bristol and will be based in Cambridge. Applicants with experience in parallel computing or structure determination using NMR spectroscopy/X-ray diffraction would be particularly welcome. However, candidates with other relevant backgrounds are encouraged to apply. The post is available (starting date negotiable) at a starting salary within the range 9,305 - 13,675 pounds (according to age and experience). Applicants should apply before 31st June, sending a full C.V. and naming two academic referees, to Dr. E.D. Laue, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, U.K., (telephone Cambridge 333677) from whom further details may be obtained. UNIVERSITY OF CAMBRIDGE DEPARTMENTS OF CHEMISTRY AND BIOCHEMISTRY RESEARCH STUDENTSHIP IN NMR SPECTROSCOPY/PROTEIN STRUCTURE DETERMINATION Applications are invited for a 3 year Ph.D. studentship available from October 1988 and funded by the SERC for work on the development of NMR spectroscopic methods for protein structure determination. Applicants should have, or expect to obtain, a first or upper second class honours degree in Chemistry or Physics. Further information may be obtained from either Dr. J. Keeler (Department of Chemistry; Tel: Cambridge 336428) or Dr. E.D. Laue (Department of Biochemistry; Tel: Cambridge 333677). Applicants should send a full Curriculum Vitae and the names and addresses of two academic referees, as soon as possible, to either of the above.