MJB1%BIO.CAM.AC.UK@CUNYVM.CUNY.EDU (11/11/88)
Molecular biology computing course
A two day course providing a general practical introduction to some of the
uses of computers in Molecular Biology will be held on the 21st and 22nd of
November in Room 204 of the Genetics Building in the Downing Site.
The course will be repeated on the 23rd and 24th November. There is 1 place
available for the 21st/22nd course and 7 places for the 23rd/24th course.
If required, the course will be repeated on the 28th and 29th November.
The provisional program, in outline, is as follows:
Day 1: 9.30 - 13.00, 14.00 - 17.30
- Compute restriction fragment sizes from an agarose gel photograph
- Predict possible restriction maps from the computed restriction fragment
sizes
- Read sonicated sequences from autoradiographs using a digitiser
- Use the Staden DB System (the PC based version) to reassemble those
sequences
- Use the Staden programs (the PC based version) to variously analyse the
reassembled sequence
- Transfer the reassembled sequence to the CSBS VAX (BIO)
- Search a DNA sequence database stored on BIO for homologous sequences
- Further investigate interesting homologies using the Staden programs (the
VAX version).
Day 2: 9.30 - 13.00, 14.00 - 17.30
- Predict the secondary structure of an RNA sequence
- Probe a protein sequence database (stored on the PC) for sequences
homologous to a given sequence.
- Further investigate interesting homologies using the Staden programs (the
PC version).
- Investigate the potential function of a protein sequence
- Predict the secondary structure of a protein sequence
The teaching laboratory for the course includes seven workstations based on
IBM PCATs. During the course the workstations will be used as stand alone
machines and as terminals to the Cambridge IBM 3084 mainframe (PHX) and BIO.
Some of the IBM PC programs that are used are public domain programs copies
can be provided.
Temporary IBM 3084 (Phoenix) and VAX projects will be available for course
participants who do not have their own. Application forms for personal
projects will be available.
The course is free to all who would like to attend. If you would like to
come on the course please contact
David Judge,
Department of Genetics,
University of Cambridge,
Cambridge.
Telephone: Not yet installed, messages can be left at ext 3999
(Cambridge 333999, from outside the University)
Email : DPJ10@UK.AC.CAM.PHX
DPJ10@UK.AC.CAM.BIO