MBFBPED@cms.manchester-computing-centre.ac.uk (11/30/89)
WE ARE IN THE PROCESS OF BUILDING UP A DATABASE OF EXPERIMENTALLY
DETERMINED T CELL EPITOPES. WE FEEL THAT SUCH A DATABASE
PROVIDE DATA WHICH WOULD HELP TO UNDERSTAND AND PREDICT T CELL
EPITOPES AND MHC RESTRICTION ON THE BASIS OF SEQUENCE - IT WOULD
ALSO BE USEFUL IN THE DESIGN OF CARRIER-FREE VACCINES. THE DATA,
ONCE COLLECTED, WILL BE FREELY AVAILABLE TO MEMBERS OF THE ACEDEMIC
COMMUNITY. IF PEOPLE HAVE T CELL EPITOPE DATA THEY WOULD LIKE TO
SEND TO US, WE WOULD BE MORE THAN HAPPY TO RECEIVE IT.
COULD PEOPLE PLEASE E-MAIL DETAILS OF:
NAME, ADDRESS, AND ANY CITATIONS
THE PROTEIN CONTAINING THE EPITOPE
THE EPITOPE ITSELF
THE EXPERIMENTAL TECHNIQUE USED (E.G. PEPSCAN)
ANY MHC RESTRICTION
THE ANIMAL MODEL USED
THANKS IN ANTICIPATION,
DR. A. BRASS
DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
UNIVERSITY OF MANCHESTER
STOPFORD BUILDING
OXFORD ROAD
MANCHESTER M13 9PT
UK
E-MAIL ADDRESS: MBFBPED@MCC.CMS