JF600@albnyvms.bitnet (06/01/90)
+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + CONFERENCE ANNOUNCEMENT "CONVERGING APPROACHES IN COMPUTATIONAL BIOLOGY" SEPTEMBER, 13-16, 1990 RENSSELAERVILLE, NY An interdisciplinary meeting on "Converging Approaches in Computational Biology" will be held September 13-16, 1990 in Rensselaerville near Albany, New York, under the auspices of the Center for Molecular Genetics of the State University of New York at Albany. The concept of the meeting reflects an increased awareness within the scientific community that computational tools being developed in diverse fields have common elements or close analogies. The aim of the conference is to identify these elements and to facilitate an exchange among computational biologists that is not normally possible within the constraints of topical, single-discipline meetings. The meeting will bring together about 100 scientists working in a wide range of disciplines (such as x-ray crystallography, electron microscopy, sequence analysis, neurophysiological signal processing) with the purpose of encouraging interdisciplinary exchange on underlying concepts of mathematical modeling and techniques of numerical analyses in biology. To this end, the meeting is organized into sessions according to particular mathematical or computational themes: Latent Feature Identification, Information Theoretical Approaches, Methods for Reconstruction and Refinement, Simulations and Modelling, Discovery of Patterns. CONFERENCE SITE The conference, one of the Albany Conference series held annually since 1984, will take place at the Rennselaerville Conference Center, located 30 miles southwest of Albany, NY in the Helderberg Mountains. The Institute offers on-campus facilities including a large auditorium with all necessary audio-visual equipment, and smaller conference halls for informal workshops and poster sessions. The Weathervane Restaurant, located on-campus and formerly the carriage house of the Huyck estate, provides meals and refreshments, while overnight lodging is available in the modern and classic estate houses. Rooms are assigned in advance to registrants, and transportation to and from Rensselaerville is provided from the airport, as well as train and bus stations. The rural, secluded setting of the conference, the limited number of participants and the scheduling of sessions in the morning and the evening -- leaving the afternoons free -- are intended to facilitate informal discussions among conference participants. CONFERENCE FORMAT The conference will consist of three morning and two evening sessions over a period of three nights and days (Thursday evening through Sunday morning). Each session will be devoted to a particular computational theme and will be comprised of four or five 30-minute talks by experts from different biological disciplines (with strong representation from structural biology), interspersed by question-and-answer periods of 15-20 minutes. There will be an open-ended discussion period at the end of each session, with the speakers and chair serving as a panel. CONFERENCE PROGRAM The following is a summary (as of May 25) of the sessions planned for the meeting on Computational Biology. All of the speakers and most of the session chairs are indicated. SESSION 1. METHODS FOR RECONSTRUCTION AND REFINEMENT Chair: Dr. Mario Amzel, Johns Hopkins University Speakers: Dr. Sarah Nelson Fox Chase Cancer Center Peaks, patterns and protein structures from high resolution NMR spectra Dr. A.B. Goncharov Academy of Sciences, USSR Determination of angles among randomly oriented particles of unknown structure Dr. Lynn Ten Eyck General Atomics Image reconstruction and model refinement in protein crystallography Dr. John Kuriyan Rockefeller University Application of molecular dynamics to crystallographic refinement of proteins SESSION 2. INFORMATION THEORETICAL APPROACHES Chair: Dr. Andrew McLachlan, Univ. of Cambridge Speakers: Dr. Joel Trussel North Carolina State Univ. Set theoretic approaches to estimation and identification Dr. Michael Unser National Institutes of Health Optimum resolution conversion and scale-space representation of images Dr. Bi-Cheng Wang Univ. of Pittsburgh Resolution of phase ambiguity in macromolecular crystallography by a noise filtering process Dr. Temple Smith Dana Farber Cancer Inst. Identification of functional pattern correlates SESSION 3. LATENT STRUCTURE IDENTIFICATION Chair: Dr. Fred Cohen, Univ. of California, San Francisco Speakers: Dr. Pat Argos European Molecular Biology Laboratory Comparing protein sequences, sensitive methods and realistic evaluations Dr. Peter Franaszczuk University of Maryland Direction of postsynaptic potentials in intracellular recordings from neurons in tissue culture Dr. Joachim Frank Wadsworth Center, NYS Health Dept. Classifying noisy projections of an unknown structure Dr. Charles Lawrence Wadsworth Center, NYS Health Dept. Analysis of misaligned data with application to sequence analysis and neurophysiology Dr. Gary Stormo Univ. of Colorado Identifying functional domains in biological sequences SESSION 4. SIMULATIONS AND MODELLING Speakers: Dr. Ken Dill Univ. California, San Francisco Statistical mechanics of protein folding Dr. Jeff Skolnick Scripps Research Inst. Models of globular protein folding Dr. Richard Feldman National Institutes of Health Could we ever design a biology Dr. Kathleen Palmer Cornell University Modelling "loops" of proteins: homology and energy-based methods and applications SESSION 5. DISCOVERY OF PATTERNS Speakers: Dr. Alan Lapedes Los Alamos National Laboratory Neural nets, optimization and statistics: a biological case study Dr. Michael Liebmann Amoco Technology Co. Application of neural networks to structure-function analysis in proteins Dr. Teresa Webster Arris Pharmaceutical Identification of structure/function patterns using amino acid sequence information Dr. Andrew McLachlan Univ. of Cambridge Periodic structural patterns in proteins + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + REGISTRATION INFORMATION CONFERENCE FEE: $450 includes registration, accomodations (double occupancy), meals and transportation between the conference center and Albany airport. A limited number of single occupancy accomodations are available for an extra $100. Payment of the full fee will be required by AUGUST 23, 1990. Please note that neither the Albany Conferences nor the Rensselaerville Conference Center accepts credit cards. APPLICATION DEADLINE: July 30, 1990. For further information and a copy of the application form for the 1990 Albany Conference on "Converging Techniques in Computational Biology", please call the conference coordinator, Carole Keith, 518-442-4327, FAX 518-442-4767, or write to The 1990 Albany Conference, P.O. Box 8836, Albany, NY 12208-0836.