eddy@boulder.Colorado.EDU (Sean Eddy) (05/10/91)
Could some kind and wise soul please summarize some of the software available to do molecular mechanics and molecular dynamics (energy minimization, etc.) on mid-sized biomolecules? We are interested in trying to model possible tertiary structures of small RNA molecules, 20-50 nucleotides in length, starting from secondary structure constraints. Our departmental facility currently uses the BIOSYM Discover/Insight package on an IRIS workstation. The bulk of the computing facility here is oriented towards DEC hardware, however, and we are particularly interested in software that can be used on our more plentiful DECstations than the scarce IRIS station. Thanks much, - Sean Eddy - Dept. of Molecular, Cellular, Developmental Biology - U. of Colorado at Boulder - eddy@boulder.colorado.edu