SYEH@BIONET-20.BIO.NET (Spencer Yeh) (03/28/89)
Dear Biologists, New versions of the following contributed software programs are now available from the BIONET Lending Library: GELFRAGSIZER version 1.4 A Macintosh Hypercard stack to calculate gel fragment sizes from their mobilities. SEQAID version 3.5 Latest version of Don Roufa's multifunctional MS-DOS sequence analysis package adds a Needleman-Wunsch gapped alignment module and a context sensitive help facility. The site-search module now permits use of multiple search templates in a single search to emulate double or triple digests. The sequence editor now permits internal subsequence extractions. ALN3 and ALP3. BIONET version 1.0 The BIONET versions of Osamu Gotoh's triple alignment programs have been modified to search for sequences in the current connected directory instead of a fixed directory on a diskette drive. This earlier convention caused much confusion among users. Source code is now available. PCFOLD version 4.0 Michael Zuker's RNA structure prediction program has been improved by incorporating the energy model of Turner, et. al. (1987). A new separate program is provided to produce different energy files for different temperature levels. The maximum sequence limit is still 425 bp. All four of these programs are now available free of charge by anonymous FTP from the net.bio.net computer, or, for BIONET subscribers only, by postal mail. (Send a self-addressed, stamped return envelope along with a FORMATTED diskette to: BIONET Administrator; BIONET/ IntelliGenetics; 700 East El Camino Real; Mountain View, CA 94040). Help topics for all of these programs are available on the BIONET DEC2065 computer. Sincerely, Spencer Yeh Internet: syeh@bionet-20.bio.net Applications Analyst (for BIONET issues) BIONET (415) 962-7338 -------