JMULLINS@BIONET-20.BIO.NET (JAMES MULLINS) (07/13/88)
My apologies to those of you who are seeing this for a second time. Postdoctoral and Senior Postdoctoral Positions Available Starting and advanced postdoctoral positions are available now for studies directed toward identifying the pathogenic and host-cell specific consequences of genome variation in AIDS retroviruses. These studies will involve HIV as well as the simian and feline lenti-retrovirus analogs. The initial focus of the study will be to molecularly clone proviruses using lambda and PCR methodologies, determine their nucleotide sequence using automated procedures, and establish the biological activity of cloned viruses in cell culture systems. These new studies will parallel established and ongoing avenues of investigation in our laboratory [cf. Overbaugh et al, Science 239:906-910 (88); Riedel et al, Proc. Natl. Acad. Sci. 85:2758-2762 (88); Hirsch et al, Cell 49:307-319 (87); Kornfeld et al, Nature 326:610-613 (87)]. Starting post docs are requested to participate in these studies for one to two years after which they might move on to the structure-function consequences of genome variation or other projects of their own design. One position is available for an individual to train other investigators and manage the larger DNA sequencing project from the standpoint of coordination of data generation and analysis. This person will be expected to have substantial experience in dideoxynucleotide sequencing, the use of micro, mini, and/or mainframe computers, and the computer programs relevant to analysis of DNA and protein sequence information, including the IG suite. Additional positions are available for the study of the biochemical mechanisms of induction of immunodeficiency and aplastic anemia by feline leukemia virus variants [cf. Overbaugh et. al. and Riedel et. al., above]. Interested individuals should forward a statement of interests, CV and approximately three letters of recommendation to: James I. Mullins Associate Professor of Virology Department of Cancer Biology Harvard University School of Public Health 665 Huntington Ave. Boston, MA 02115 (617) 732-2167 -------