uig@cxa.daresbury.ac.uk (Computer User Support) (12/21/89)
St.GEORGE'S HOSPITAL MEDICAL SCHOOL
(University of London)
MOLECULAR GENETICS OF ATYPICAL MYCOBACTERIA IN HUMAN AND
ANIMAL DISEASES.
5 YEAR SENIOR RESEARCH FELLOWSHIP
Applications are invited for this post which is for 5 years with
a starting salary of up to 18,315 pounds sterling including
London allowance. Atypical mycobacteria are widely involved in
diseases of animals and birds including ileitis/colitis.
Evidence for their involvement in human conditions such as
Crohn's disease and rheumatoid arthritis is accumulating. We
have recently identified and characterised the first of a novel
family of specific DNA insertion sequences IS900 (Nucl. Acids
Res. 17, 9063-73, 1989) in a human disease isolate of M.
paratuberculosis, which permits the rapid and precise
identification of these agents. The molecular biology and
function of these IS and their involvement in mycobacterial
pathogenicity and disease states is to be investigated.
Applications together with two referees to Professor John Hermon-
Taylor, Department of Surgery, St. George's Hospital Medical
School, Cranmer Terrace, London, SW17 ORE, 01-767-7631, from
whom further particulars may be obtained.