dcoplin@magnus.acs.ohio-state.edu (David L Coplin) (04/13/91)
POSTDOCTORAL RESEARCHER THE OHIO STATE UNIVERSITY DESCRIPTION OF WORK This is a USDA-funded project to carry out research on the biochemical genetics of extracellular polysaccharide (EPS) biosynthesis in Erwinia stewartii, a bacterial pathogen of corn. EPS is the major virulence factor of this pathogen and this is one of only a few systems in which the genetics of EPS synthesis is fairly well characterized. The individual will construct defined EPS mutants by site-directed mutagenesis of previously cloned EPS genes, further develop a "cell-free" system for radiolabeling EPS in cell extracts, and characterize the lipid-linked oligosaccharide intermediates accumulated by the EPS mutants. QUALIFICATIONS Ph.D. in a biological science with experience in general biochemistry and/or molecular biology. STARTING DATE Immediate opening. This is a two-year position. CONTACT Dr. David Coplin Department of Plant Pathology The Ohio State University 2021 Coffey Road Columbus, OH 43210-1087, USA 614-292-8503 Internet dave+@osu.edu dcoplin@magnus.acs.ohio-state.edu Bitnet dave+@ohstmail