agostino@med.unc.edu (Michael Agostino) (04/24/91)
I am seeking a postdoctoral fellowship. I anticipate completing my doctoral studies by August 1, 1991. In graduate school, my primary focus was the molecular evolution of the mammalian transposable element L1. These studies included a significant amount of general molecular biology techniques, DNA sequencing, and computer analysis of the resultant data. My secondary projects included the development of a number of novel techniques. In addition, I have some experience with RNA isolation and manipulation, production of monoclonal antibodies, mammalian cell culture transfections, and isolation of DNA from tissue (please see attached C.V.). As a postdoctoral fellow, I would like to use my molecular biology training to manipulate the biology of a system, as compared to characterization studies like those that I have been involved with. I realize this is a rather vague description of my interests but I feel a lot of topics could be interesting and would like to see what is available. I would greatly prefer a position in the western United States. If you or someone you know has a postdoctoral position available and would like to know more about me, I can send preprints of my publications, a more complete description of my work in progress, and I can arrange for confidential letters of reference to be sent. Thank you for your time. Curriculum Vitae Nils Breton Adey Address: Dept. of Microbiology and Immunology Campus Box 7290 University of North Carolina at Chapel Hill Chapel Hill, NC. 27599. Telephone: 919-966-5476 E-Mail: Adey@UNCVX1.Bitnet Birthday: Sept. 14, 1960 Education: 7/85 - present: Ph.D. program in the Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill under the direction of Dr. Clyde A. Hutchison III 8/79 - 5/83: B.S. in chemistry from Carnegie-Mellon University, Pittsburgh, PA. Related Employment: 1/85 - 6/85: Melloy Labs, Springfield, VA. Contract molecular biology services: DNA sequencing, clone isolation from provided libraries, and subcloning. 10/83 - 12/84: Genex Corp., Gaithersburg, MD. Development of assay for methyltransferase; mutagenesis and isolation of yeast strains that overproduce phenylalanine ammonia lyase; characterization of novel proteases from bacteria isolated from the environment. Publications: 1. A Rapid and Versatile Method to Transfer an Insert Between Single-Stranded Vectors and Reverse its Orientation. N. B. Adey and C. A. Hutchison III (1991) Nucleic Acids Res. (in press) 2. Nucleotide Sequence of a Full-Length F-Type L1 Element. N. B. Adey, M. B. Comer, M. H. Edgell, and C. A. Hutchison III (1991) Nucleic Acids Res. (in press) 3. Nucleotide Sequence of the BALB/c Mouse b-Globin Complex. W. R. Shehee, D. D. Loeb, N. B. Adey, F. H. Burton, N. C. Casavant, P. Cole, C. J. Davies, R. A. McGraw, S. A. Schichman, D. M. Severynse, C. F. Voliva, F. W. Weyter, G. B. Wisely, M. H. Edgell and C. A. Hutchison III (1989) J. Mol. Biol. 205, 41-62. Submitted manuscripts: 1. A Composite of A and F-Type 5' Sequences Defines a Subfamily of Mouse L1 Elements. N. B. Adey, S. A. Schichman, C. A. Hutchison III, and M. H. Edgell (1991) J. Mol. Biol. (submitted April 1991). Manuscripts in preparation: 1. The Structure and Evolution of the 5' End of L1 Elements in Mouse. N. B. Adey, S. A. Schichman, M. H. Edgell, and C. A. Hutchison III. Presentations at scientific meetings: 1. Either A or F-type 5' Repeats are Associated with the Same Subfamilies of L1 in Mus domesticus. Workshop of LINE-1 Related Transposable Elements, Carnegie Institution of Washington. Oct. 9-11, 1989. 2. LINE-1 Elements in Mus domesticus Contain Two Polymorphic Regions Which Vary Independently. 16th Molecular and Biochemical Genetics Workshop, Park City, Utah. April 5-8, 1989.