VCORCES.BISHOP@BIONET-20.BIO.NET (John Bishop) (01/08/89)
Dear Genbank-bb, I received a message that my first message was lost in part of the mail network. I will reinsert the body of that text here. Dear Genbank-bb, Seems that people are in need of the translated database searching capability mentioned here in this bb by James Fickett and others a while back. Also seems Henikoff and Wallace have hit on a good AT class computer version of such searches (Nuc Acids Res 16(13):6191). I have heard that people are sending their stuff to Genentech to be done in such a fashion. $$$$? Are these plans being implemented? or should I get on the phone to Steve Henikoff now? John Bishop Sorry if this is redundant. I do not mean disrespect by the previous message I was too sarcastic I'm afraid! Perhaps that is why the message was lost! John Bishop -------
wrp@biochsn.acc.virginia.edu (William R. Pearson) (01/09/89)
> Seems that people are in need of the translated database searching >capability mentioned here in this bb by James Fickett and others a while back. One of the standard parts of the FASTA sequence search package (Pearson and Lipman, PNAS (1988) 85:2444) is a program called TFASTA, which compares a protein sequence to a DNA sequence (or library of sequences) by translating the DNA sequence in all six frames. The FASTA package is available for downloading to UNIX computers over the arpanet from the host uvaarpa (ftp uvaarpa, login as anonymous, get the file public_access/fasta.shar) or on floppy disks for the IBM-PC and the Macintosh for $60.00 prepaid, $85.00 P/O, with complete source code. Send checks to: William R. Pearson 1611 Westwood Rd. Charlottesville, VA 22901