[sci.med.aids] PCP prophilaxis

Wounded.Bird@f38.n135.z1.fidonet.org (Wounded Bird) (01/07/90)

A friend of mine returned from a weekly meeting of doctors who specialize in  
AIDS treatment with the news that the results of efficacy trials of the various  
PCP prophilaxis were out. He stated that Aerosol Pentam at 300 mg administered  
once a month resulted in a very low 20% rate of reinfection in the lungs.  
However, 60mg administered twice a month resulted in only a 10% rate of  
reinfection.

The problem with aerosol pentam is that it is not a systemic treatment and they  
are running into pcp infections of the ears, throat, spleen and liver. Oral  
Bactrin seems to be the preferred method of prophilaxis however a large number  
of people are allergic to it.

If anyone has more detailed and/or authoritative information please post it!

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