UUCP@stjhmc.fidonet.org (UUCP) (10/03/90)
but some infectious virus is still present since release of virus was seen on day 10. This result indicates that the virus is resistant at room temperature, either in dry form or liquid medium. This resistance of LAV at room temperature may explain the appearance of some cases of AIDS cases in non-risk groups. To prevent possible contami- nation by viral particles in dry or liquid form hygiene should be increased in the general population. Moreover, some more safety precautions should be taken in laboratories and in hospitals and by dentists who use a vacuum pump for saliva aspiration. Indeed, these data strongly support the use of disinfectants found to be effective against the AIDS agent. -- F. Barre-Sinoussi et al., "Resistance of AIDS Virus at Room Temperature," _Lancet_, 28 September 1985, pp. 721-722 Shortly after this study, researchers from the laboratory of Tumor Cell Biology, National Institutes of Health and elsewhere reported findings on the stability of concentrated amounts of the AIDS virus: In view of the serious consequence of HTLV-III/LAV infection, its stability under clinical and laboratory conditions and its inactivation by commonly utilized inactivating agents and disinfectants are of tremendous importance to health care workers and laboratory personnel. Here, the results of testing the stability of HTLV-II/LAV under various experimental conditions are reported. . . . To test the effect of some frequently encountered clinical and laboratory conditions on the infectivity of the HTLV-III (TM), virus diluted in media supplemented with 50% human plasma was dried and incubated at 23 to 27 degrees Centigrade, or incubated in an aqueous temperature (23 to 27 degrees Centigrade), 36 to 37 degrees Centigrade, and 54 to 56 degrees Centigrade for various periods of time. In a dried state, complete inactivation of virus required between three and seven days. . . . Exposing virus to different temperatures resulted in a reduction of infectious virus corresponding to increasing times of incubation and increasing temperatures. Complete inactivation . . . of infectious virus was seen between 11 and 15 days of exposure at 36 to 37 degrees Centigrade. Infectious virus was still detected after 15 days at room temperature. . . . Infectious cell-free virus could be recovered from dried material after up to three days at room temperature, and in an aqueous environment (e.g., water), infectious virus survived longer than 15 days at room temperature. Even under the more rigorous heating conditions commonly used to inactivate complement (54 to 56 degrees Centigrade), infectious virus was detected three hours after exposure. . . . The stability of HTLV-III at 54 to 56 degrees Centigrade suggest that the inactivation of virus in blood products (e.g., antihemophilia factors) could require more extensive treatment, as has been suggested. -- L. Resnick et al., "Stability and Inactivation of HTLV-III/LAV under Clinical and Laboratory Experiments," _JAMA_ 1985:225:1897-1891. -- +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ + *READ* ---> The opinions expressed above are to the best of my knowledge, + + however all options should be discussed with persons who have professional+ + training with the subjects covered here. * ALL POSSIBLE DISCLAIMERS APPLY!+ + ____FROM: chguest@pioneer.arc.nasa.gov =>or<= sun!ames!pioneer!chguest____+ +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ + Heavy Japanese trade tariffs prevent the sale of U.S. made goods in Japan.+ + Buy products manufactured in _AMERICA_ the job you save could be your own.+ +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ -- +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ + *READ* ---> The opinions expressed above are to the best of my knowledge, + + however all options should be discussed with persons who have professional+ + training with the subjects covered here. * ALL POSSIBLE DISCLAIMERS APPLY!+ + ____FROM: chguest@pioneer.arc.nasa.gov =>or<= sun!ames!pioneer!chguest____+ +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ The Soviets have always been gifted chess players and strategists. Let us be diligent in watching our pieces and the game very carefully. . +++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ -- Uucp: ...{gatech,ames,rutgers}!ncar!asuvax!stjhmc!UUCP Internet: UUCP@stjhmc.fidonet.org