toms@fcs260c2.ncifcrf.gov (Tom Schneider) (12/10/90)
I have made my sequence logos available to everybody, and since they are in PostScript, I thought I'd mention it here. They are a method for displaying variable patterns in DNA and Protein sequences. A while back I was struggling with how to create stacks of letters on top of one another. (Thanks to help from several people in this group, I eventually solved the problems completely.) The stack represents the possible letters at each position. The height of the stack is the importance or consistency of preservation of the pattern. The individual letters are proportional to their frequencies in the original sequences. The logos are fun to look at and play with. They are in color and will come out shades of grey on a black and white printer. If you would like to see them, you can obtain them by anonymous ftp from ncifcrf.gov in pub/delila. The README file describes all the programs and tools available, but if you just want to see them, get one or all of: ribo.logo.Z t7.logo.Z lambcro.logo.Z globin.logo.Z The .Z means that they are compressed. Have fun! Tom Schneider National Cancer Institute Laboratory of Mathematical Biology Frederick, Maryland 21702-1201 toms@ncifcrf.gov