[net.general] Caffeine: Birth Defects and More

jmg@houxk.UUCP (11/02/83)

	Some time ago I wrote a few articles about problems I experienced
with caffeine. Today I came across a little pamphlet called "Caffeine:
Birth Defects and More" by Dr. Ronald W. Thompson, Director, Nutritional
Education, General Nutrition Corporation, 1301 39th St. N., Box 349,
Fargo, ND 58107 (701) 282-2300. The text of the pamphlet is as follows:

FDA WORRIED OVER POSSIBILITY THAT CAFFEINE MAY CAUSE BIRTH DEFECTS -
REMOVE CAFFEINE FROM GOVERNMENT LIST OF SUBSTANCES "GENERALLY RECOGNIZED
AS SAFE."

	BIRTH DEFECTS CONCERN
	Recent scientific studies of the effect of caffeine on laboratory
rats have shown that caffeine can cause birth defects ranging from cleft
palate to missing toes to delayed skeletal development. Various defects could
be produced at a caffeine intake ranging from the equivalent of drinking 2 cups
of coffee to 12 to 24 cups of coffee each day; an intake that the Food and
Drug Administration feels is not far beyond the level a human might receive
from beverages and drugs.
	While not yet certain that caffeine related birth defects can occur
in humans as it does in rats, Food and Drug Commissioner Jere Goyan stated,
"The findings have caused enough concern among FDA scientists that today I am
advising pregnant women to avoid caffeine-containing food and drugs, or to use
them sparingly... The scientific evidence on caffeine is inconclusive... but
the evidence to date is sufficient for us to raise the warning flag..."
	Caffeine can cross the placenta to the developing baby. But, mothers
who nurse should know that caffeine can also get into breast milk. Mothers
should be concerned about the possibility of any drug getting into their milk
while they nurse, and they should remember that caffeine is a drug.

	CAFFEINE AND BREAST DISEASE
	The lumps, thickenings and nodules that appear in breasts of women with
a condition called fibrocystic breast disease are harmless (benign), but it is
difficult for a physician to definitely distinguish them from cancerous lumps
in the breast. Since the lumps are difficult to distinguish from cancerous ones
and women with fibrocystic breast disease have an increased risk of developing
breast cancer anyway, physicians frequently recommend that patients undergo the
inconvenience and discomfort of breast biopsy.
	Dr. John P. Minton and co-workers at Ohio State University Medical
School recently presented evidence that caffeine may be involved in the
development of breast lumps in fibrocystic disease. Forty-seven women with this
disease were advised to stop taking caffeine and caffeine-related substances
in both liquids and foods. Twenty women accepted this advice and 13 (65%)
experienced relief of symptoms and disappearance of breast lumps in 1 to 6
months. Of the seven who did not experience relief initially, three stopped
smoking and continued to avoid caffeine and then symptoms disappeared. Only
one of the twenty-seven women who did not take Dr. Minton's advice experienced
relief; the remaining 26 women were required to undergo biopsy to determine
if the lumps were cancerous.
	The concern over caffeine possibly causing birth defects and possible
relationship to breast disease is surprising news to most Americans. The fact
that caffeine can affect nerves is not.

	CAFFEINE NERVES
	Most Americans already know that while the first cup of coffee or tea
provides a lift to start the day, that fourth, fifth or more cup can set your
nerves jangling. This condition, known as coffee nerves or caffeinism, can
produce symptoms that include lightheadedness, heart palpitation, loose stools,
headache and inability to fall asleep or stay asleep at night.
	Including children, each American consumes an average of 200 milligrams
of caffeine each day. Half of this amount is enough to produce significant
bodily effects in most people. It has been estimated that 30% of Americans take
between 500 and 600 milligrams of caffeine per day and 10% may use more than
1000 milligrams each day.
	It is not generally known that caffeine is a weakly addictive drug and
as such can produce "withdrawal" when people stop using it. Symptoms, including
fatigue and headache, can appear 24 to 48 hours after a heavy caffeine user
quits. The headache generally can be relieved only by more caffeine. This
problem may not be uncommon in people who drink a lot of coffee or tea while
at work but quit over the weekend.
	It's not just caffeine that can cause a problem. Theobromine is a
substance that has effects on the body similar to caffeine. Theobromine and
caffeine are found in cocoa and chocolate-type products.
	If you want to cut down on caffeine there is a source besides coffee,
tea, cocoa and chocolate that you should be concerned about - soft drinks.

	WHAT ABOUT THE KIDS?
	America's desire for soft drinks is unbelievable! Almost 8 billion
gallons are guzzled each year. Most Americans aren't aware that many of these
mixtures of sweetened water, carbon dioxide and various chemical colors and
flavors also contain caffeine. In fact, two servings of three of the most
popular cola drinks contain about 72 milligrams of caffeine. A cup of tea or
coffee contains anywhere from 60 to 150 milligrams of caffeine. A single cup
of cocoa can have as much as 13 milligrams per cup.
	Most mothers wouldn't think of giving their children four or five
cups of coffee a day, yet frequently let them drink that many cola beverages.
It's not just that all that sugar isn't good for them, but all that caffeine
may be part of the reason why they can't sit still very long.
	Cocoa contains caffeine and, strangely enough, cocoa drinks are
popular evening drinks for children; supposedly to relax them before bed time.
Many parents just aren't aware that it's possible their children may actually
be drinking more caffeine than they are through "hidden" caffeine in soft
drinks and cocoa.

	THE ALTERNATIVES
	Caffeine is a central nervous system stimulant. Cutting down on it
can avoid "coffee nerves" and the problems related to it. Most of the time
a lot of coffee and tea is drunk more out of habit than anything else. You
can develop new habits that avoid the caffeine yet still provide the
satisfaction of a hot drink.
	Delicious caffeine free teas are available. These teas are not
"decaffeinated", but rather are made from herbs that do not have caffeine
in them. Herb tea mixtures contain less caffeine than than traditional black
teas, but can contain caffeine depending on the mixture. And, of course,
there are decaffeinated coffees.
	Try juice as a replacement for soft drinks, for the kids, and for
yourself. Not only are there a wide variety of tasty fruit juices but
delicious combinations as well. Try the commercially prepared selection or
mix your own combination to suit your taste. Delicious, and fun too.
	There are other advantages to using juices besides the good taste.
They contain no caffeine but do provide vitamins and minerals. You can cut
down on sugar consumption too by selecting unsweetened juices or juices
sweetened with fructose or honey.
	Take care of yourself and the children. Cut down on drinking caffeine.
Use caffeine free tea, decaffeinated coffee or juice.

	CAFFEINE AND RELATED SUBSTANCES IN FOODS:

				milligrams per cup
Coffee
	instant				61-70
	percolated			97-125
	drip				137-153

Tea
	weak				8
	strong				46
	instant				31

Cocoa					13

				milligrams per 12 oz.
Carbonated soft drinks
	Coke				65
	Tab				50
	Pepsi				43
	Mountain Dew			55

Other foods
	Almond milk chocolate bars	about 6 milligrams caffeine
	brownies			and 60 milligrams theobromine
	other chocolate candy		per oz.
	sweet chocolate sauce

Chocolate-flavored
	cake, roll cake,		about 3 milligrams caffeine
	cookies, chiffon pie,		and 30 milligrams theobromine
	parfait, doughnuts,		per oz.
	candy bars, peanut butter cups