kenny@uiucdcsb.cs.uiuc.edu (10/20/86)
/* Written 12:34 pm Oct 6, 1986 by dlbaer@helm.UUCP in uiucdcsb:net.med */ /* ---------- "Treating ANXIETY DISORDERS does any" ---------- */ I have read a book by Dr. Harold N. Levinson called PHOBIA FREE and he practices out of Great Neck,NY. He does not accept MEDICARE and he charges $750 for inner ear tests and then treats you with DRAMAMINE and other antimotion sickness drugs. /* End of text from uiucdcsb:net.med */ Sounds a trifle peculiar to me. Anyone out there have information about this? I suspect that Dr Levinson is taking advantage of the sedative effect of scopolamine (the active ingredient in Dramamine, Triptone, and several other over-the-counter anti-nausea agents). I know that I have never been able to use Dramamine; the sedative effect hits me more strongly than most. I am totally zonked out before I have enough dosage to control motion sickness (and being sedated and nauseated together is no fun at all!). Fortunately, I haven't suffered from motion sickness since my astigmatism was corrected. In any case, claiming that Dramamine is not psychotropic is a lie. Kevin Kenny UUCP: {ihnp4,pur-ee,convex}!uiucdcs!kenny University of Illinois at Urbana-Champaign CSNET: kenny@UIUC.CSNET ``Don't worry; I'm a New Yorker!'' ARPA: kenny@B.CS.UIUC.EDU (kenny@UIUC.ARPA)
dyer@spdcc.UUCP (Steve Dyer) (10/22/86)
>Sounds a trifle peculiar to me. Anyone out there have information about >this? I suspect that Dr Levinson is taking advantage of the sedative effect >of scopolamine (the active ingredient in Dramamine, Triptone, and several >other over-the-counter anti-nausea agents). I know that I have never been >able to use Dramamine; the sedative effect hits me more strongly than most. >... >In any case, claiming that Dramamine is not psychotropic is a lie. The active ingredient in Dramamine is not scopolamine, it's dimenhydrinate, an unusual salt of diphenhydramine (aka Benadryl) and 8-chlorotheophylline. Diphenhydramine is an antihistamine with pronounced sedative and anti-motionsickness effects. Why they don't sell diphenhydramine for motion sickness is beyond me; presumably the xanthine moiety was incorporated in dimenhydrinate for its stimulant effects a la caffeine. In any event, whatever stimulation the 8-chlorotheophylline contributes is minor, and Benadryl and Dramamine can be considered equivalent drugs when taking into account the amounts of diphenhydramine in each (50mg of Dramamine is roughly equivalent to 25mg of Benadryl.) Antihistamines like diphenhydramine as well as scopolamine are all thought to produce their sedation through anticholinergic effects in the brain. Although there's no doubt that they'll make you sleepy (in fact, diphenhydramine was recently approved by the FDA as an over-the-counter sleeping aid) there's a lot of evidence that they have litte, if any, effect on anxiety. Someone with a true anxiety disorder would probably feel very sleepy but remain anxious after taking one of these drugs. The sedation is not at all reinforcing; it does not resemble the euphoria produced by minor tranquilizers. -- Steve Dyer dyer@harvard.HARVARD.EDU {linus,wanginst,bbnccv,harvard,ima,ihnp4}!spdcc!dyer