[sci.med] HICN232 News Part 1/5

ATW1H%ASUACAD.BITNET@oac.ucla.edu (Dr David Dodell) (09/05/89)

--- begin part 1 of 5 cut here ---
Volume  2, Number 32                                      September  4, 1989

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                         Editor: David Dodell, D.M.D.
                   St. Joseph's Hospital and Medical Center
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     (c) 1989 - Distribution on Commercial/Pay Systems Prohibited without
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                       T A B L E   O F   C O N T E N T S

1.  Medical News
     Medical News for Week Ending September 3, 1989 ........................  1

2.  Center for Disease Control Reports
     [MMWR 8-31-89] Motor Vehicle Crashes in Indian Community ..............  8
     Measles Outbreak  ..................................................... 11
     Characteristics of Persons Who Died From Heart Diseases ............... 12
     Rabies Surveillance,United States, 1988  .............................. 14

3.  Dental News
     Dental News from the American Dental Association ...................... 22

4.  Columns
     Black Bag Bulletin Board List ......................................... 27

5.  Articles
     International Diabetes Epidemiology Newsletter ........................ 38

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Volume  2, Number 32                                      September  4, 1989

===============================================================================
                                 Medical News
===============================================================================

                Medical News for Week Ending September 3, 1989
       Copyright 1989 -- USA TODAY/Gannett National Information Network
                          Reproduced with Permission

                                      ---
                                August 28, 1989
                                      ---

                           DIETERS SHOULD EAT ALONE:

   People dieting to lose weight might be better off eating alone  than  in  a
group,  new  research  suggests.  A  study  of  63  dieters  at  Georgia State
University found that meals eaten with other people contained 30 percent to 40
percent more calories and more fat.  (From the USA TODAY Life section.)

                         SURVEY - COMPARE DRUG PRICE:

   A new survey conducted by the American Association of Retired Persons found
that drug prices could vary widely, even within the same town. The association
asked  1,050 pharmacies in 42 states for prices of 15 prescription drugs.  The
survey found that overall,  shopping around for prescription drugs could  save
up to 25 percent. (From the USA TODAY Life section.)

                        BRAND NAMES TWICE AS EXPENSIVE:

   Brand  name drugs cost about twice as much as generics,  according to a new
survey. The American Association of Retired Persons polled 1,050 pharmacies in
42 states,  asking them to provide prices for 15 common brand name and generic
prescription drugs.  The poll also found that prices for the same generic drug
varied as much as 1,400 percent across the country.  (From the USA TODAY  Life
section.)

                          HORMONE LINKED TO DIABETES:

   Researchers  have  uncovered  a  hormone  that  might be a key agent in the
development of diabetes,  Thursday's New England Journal of Medicine  reports.
The  hormone,  islet amyloid polypeptide,  is commonly called IAPP.  A team of
researchers found that it might impair insulin's  ability  to  regulate  blood
sugar levels, causing Type 2 diabetes, the disease's most common form.

                         ALLERGIES STILL TOP PROBLEM:

   Despite  advances  in medicine,  allergies remain one of the United States'
most common health problems, an expert said this week. Dr. M. Eric Gershwin of
the University of California,  Davis,  said  one  out  of  six  U.S.  children
suffered  allergies  to  any of hundreds of everyday items.  He said allergies
shouldn't be ignored and could be treated effectively.

                          JURY BELIEVES THE DETAILS:

   Witnesses who remember details are often are more convincing to a jury than

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Volume  2, Number 32                                      September  4, 1989

those who don't.  Two University of Washington psychologists found that  study
participants  who  heard testimony from two witnesses to a store robbery sided
with the witness who remembered the candy a bystander brought to the  counter,
weather the witness testified for the prosecution or the defense.

                            FOOD STRETCHES STOMACH:

   Experiments  might  have  proven  the  long-held  belief  that  the stomach
literally stretches after large meals.  Doctors at Roosevelt Hospital  in  New
York City inserted balloons into the stomachs of 11 patients,  then filled the
balloons with  water  until  patients  said  they  felt  full.  The  September
Hippocrates  magazine  reports  that  obese  patients consumed 90 percent more
water than lean patients.

                                      ---
                                 Aug. 29, 1989
                                      ---

                        DEPRESSION LINKED TO SEX ROLES:

   Scientists cite two  reasons  to  explain  why  teen  girls  are  far  more
depressed  than  boys:  They  feel fat and they participate in more "feminine"
activities, a new study suggests.  Researchers at Princeton University studied
300 adolescents. (From the USA TODAY Life section.)

                         AGENCY WANTS PRIMATE'S BODY:

   People   for   the   Ethical  Treatment  of  Animals  want  an  independent
veterinarian to examine the body of  one  of  the  Silver  Spring  Monkeys  to
determine  the  cause of death.  The monkey,  named Paul,  was used in medical
testing and died Saturday at a Tulane University Laboratory in Louisiana. PETA
contends mistreatment by researchers led to his death.

                          PERSONAL STRESS TAKES TOLL:

   Unexpected stress caused by strangers and  uncontrolled  situations  causes
more toxic stress than extra work, family fights and a routine headaches, says
University  of Michigan sociologist Ronald Kessler.  Daily stress diaries kept
by 166 married couples for six weeks were used for the study.

                          VITAMIN C BATTLES DISEASE:

   A team of researchers has found that ascorbate,  better known as vitamin C,
appears  to  be  the  best  way to neutralize dangerous "free radicals" in the
blood.  Free radicals have been linked to the process  which  creates  artery-
clogging  plaque.  The  plaque build-up causes atherosclerosis.  The vitamin C
neutralized 100 percent of the free radicals it encountered in lab tests.

                        DRUG FIGHTS DIABETIC PROBLEMS:

   Researchers have found  that  the  drug  aminoguanidine  shows  promise  in
stopping diabetic complications.  Geritech Inc.  of Northvale, N.J., signed an
agreement Monday forming an alliance with Yamanouchi Pharmaceuticals of  Tokyo
to  develop and commercialize biomedical technology to treat health effects of
diabetes and aging.

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Volume  2, Number 32                                      September  4, 1989

                         HOPKINS TESTS NEW EYE LASER:

   Clinical tests of an experimental laser to remove scars and  irregularities
from  the corneal surface of the eye have begun at The John Hopkins Wilmer Eye
Institute.  If the tests prove safe and effective,  the  laser  surgery  could
reduce  the  need  for  corneal  transplants  in an estimated 15 percent to 20
percent of the 33,000 U.S. residents each year who undergo transplants.

                         WHO RELEASES VACCINE UPDATE:

   The World Health Organization announced that immunization against polio had
reached two-thirds of the world's population.  WHO said Monday that 67 percent
of the world's children were now immunized against the disease by their  first
birthday.  WHO's  update  on other global vaccination efforts:  diptheria,  66
percent; tetanus, 66 percent; and measles, 61 percent.

                          FEW BABIES CONTRACT HERPES:

   New research indicates that less  than  one  percent  of  infants  born  to
mothers  with  herpes  simplex  in  their  genital  tract at the time of birth
actually get the disease.  Doctors at the University of Alabama at  Birmingham
said  the study was good news for mothers who were concerned about passing the
disease to their children.  Chance of a newborn  getting  the  disease  during
birth: 0.8 percent.

                                      ---
                                 Aug. 30, 1989
                                      ---

                         MOST TEEN DEATHS PREVENTABLE:

   A  leading  education official said that 77 percent of teen deaths were the
result of high risk behavior.  Roseann  Bentley,  president  of  the  National
Association  of  State Boards of Education,  said changing risky teen behavior
would be the  focus  of  a  board  formed  to  battle  teen  health  problems.
Appointments  to  the board were expected Wednesday.  (From the USA TODAY Life
section.)

                       OTC DIET PILLS MIGHT BE HARMFUL:

   Many over-the-counter diet pills  can  be  harmful  to  heart  patients,  a
pharmacist  said this week.  Some of the pills contain phenylpropanolamine,  a
decongestant with a mild stimulant effect.  They can cause blood  pressure  to
rise,  increase  heart  rate,  and  cause  heart  palpitations,  according  to
pharmacist Judy  Shinogle  of  Washington,  D.C.  (From  the  USA  TODAY  Life
section.)

PHARMACISTS GOING PRIVATE:
   The American Society of Consultant Pharmacists reports a
growing trend in the industry: pharmacists are moving into private
practice. The organization represents about 3,000 independent
pharmacists across the nation. Typical fees: $35 to $75 for
initial consultation, including an interview with research. (From
the USA TODAY Life section.)

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Volume  2, Number 32                                      September  4, 1989

                            NEW PRODUCTS DEVELOPED:

   Seven scientists and researchers were awarded Scientific Achievement Awards
of  $10,000  from  Schering-Plough  Consumer  Operations  for  developing  new
products that range from water-resistant eyeliner pencil,  new  technology  to
produce  soft,  chewable medicated squares,  and highly protective sunscreens.
Patents are pending on some of the inventions.

                            LIVES SAVED WITH BELTS:

   Traffic Safety Now,  Inc.,  a non-profit organization promoting safety belt
use  laws,  estimates  as  many  as 80 lives will be saved and 3,000 disabling
injuries will be avoided at current belt-use levels during Labor Day  weekend.
Those numbers could be doubled if everyone buckled up, the agency said.

                           BEHAVIORS CAN HELP, HURT:

   Teasing  and  ridicule  among  adolescents  are  two  distinctly  different
behaviors,  a Cornell  University  psychologist  contends.  While  the  former
promotes self-esteem, the later destroys it.  Psychologists said teasing among
teens  showed  they're accepted,  and promoted a healthy attitude.  Meanwhile,
spiteful ridicule can be damaging to young developing characters.

                         DOCTORS TREAT DISEASE EARLY:

   Doctors at George Washington University are using a  specialized  technique
to find and treat diseases in human fetuses before they're born.  Percutaneous
Umbilical Blood Sampling involves drawing blood from the umbilical chord - the
baby's life line to its mother -  and  testing  it  for  evidence  of  various
diseases. If any are found, treatments to fight them could begin before birth.

                         PEDIATRICIANS CAN SPOT ABUSE:

   A  new  survey by doctors at Johns Hopkins Children's Center indicates that
most pediatric training programs  don't  train  physicians  to  recognize  the
telltale signs of alcohol and drug abuse.  The survey said pediatricians,  who
often continue to see patients through adolescence,  were  in  a  position  to
recognize changes that indicate abuse.

                                      ---
                                 Aug. 31, 1989
                                      ---

                           PHARMACISTS CALM CALLERS:

   Hundreds of callers phoned the USA TODAY hot line Tuesday inquiring about a
generic  blood  pressure  drug  replacement  for  Dyazide  produced  by  Bolar
Pharmaceutical Co.  under government scrutiny.  The drug  hasn't  been  proven
unsafe or ineffective and remains on the market for now,  without the Food and
Drug Administration's recommendation. (From the USA TODAY Life section.)

                            BROCCOLI FIGHTS CANCER:

   Broccoli and its related family of cruciferous vegetables - brussel spouts,

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Volume  2, Number 32                                      September  4, 1989

cauliflower and cabbage family - are considered to  be  anti-carcinogens.  The
vegetables  can  be found year round in markets.  Broccoli is best in the late
summer and early autumn, dietitians say.

                         STUDY TARGETS HELPFUL DRUGS:

   Scientists at Biogen, Inc.  in Cambridge, Mass., recently presented studies
on  two  new  drugs  to  battle  heart  disease.  The  drugs  are hirugen,  an
anticoagulant,  and applaggin,  a protein that blocks clumping  of  platelets.
Studies  say  hirugen  might  be  safer  to  use than conventional drugs,  and
applaggin might lead to therapies for arterial thrombosis,  a cause  of  heart
attacks.

                              LAB ANIMALS SPARED:

   An  artificial  method  of  growing animal tissue is providing an effective
model for studying human diseases that once required live laboratory  animals.
Researchers  at  Cornell  University  are  using  the  process  to  study  the
sometimes-fatal blistering skin disease pemphigus  vulgaris  and  toxic  shock
syndrome with artificially grown dog skin and baboon vaginal tissue.

                           SOVIETS AID U.S. PATIENT:

   Joseph Kallu was the first U.S.  resident to be treated in a new clinic for
foreigners near the Research Institute of  Eye  Microsurgery  in  Moscow.  The
radial  keratotomy  surgery  reshaped the surface of his eyes,  correcting his
vision from 200/400 to  20/30.  The  technique  is  available  in  the  United
States, but insurance coverage for it varies.

                          REFINING LIVER-TRANSPLANTS:

   Members  of  the liver transplant team at the University of Chicago debated
the ethical issues of taking a lobe of liver from an adult  living  donor  and
transplanting it into a child in the Aug.  31 issue of the New England Journal
of Medicine.  The process  could  raise  issues  of  risk-benefit,  donor  and
recipient selection and informed consent, they said.

                        PREVENT HEAT-RELATED INJURIES:

   Athletes  should  drink  at least one cup of liquid every 20 minutes during
strenuous practice to avoid heat-related  injuries  and  practice  during  the
early  morning  or  evening  on hot and humid days.  According to the American
College of Sports Medicine,  symptoms  of  heat  injury  include:  clumsiness,
stumbling,   mental  confusion,  headache,  nausea,  dizziness,  and  lack  of
sweating.

                                      ---
                                Sept. 1-3, 1989
                                      ---
                          ROUTINE TESTING QUESTIONED:

   Routine "dipstick" testing of healthy peoplefor urinary problems results in
too many false positives to  be  useful,  conclude  two  studies  reported  in
Friday's  Journal  of  the American Medical Association.  Dipstick urinalysis,
which has been available for about 40 years, costs about $3 a test; 50 million

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Volume  2, Number 32                                      September  4, 1989

are done in the United States each year. (From the USA TODAY Life section.)

                       CANCER-DEPRESSION LINK DISPUTED:

   A new study, the first to be representative of the U.S.  population,  found
no  extra  risk  of  cancer  for people who show signs of depression.  Several
studies in recent years suggested the link.  The  study  appears  in  Friday's
issue of Journal of the American Medical Association. (From the USA TODAY Life
section.)

                           DOCTORS FIND MUTANT GENE:

   Doctors  from two universities have discovered a mutant gene that spews out
a growth hormone,  causing cancer and  occasionally  giving  rise  to  giants.
Researchers  at  the University of California-San Francisco and the University
of Milan,  Italy,  report on their findings in Thursday's issue of the British
journal Nature.

                         GROUPS JOIN ON AIDS BOOKLET:

   Fifteen major health and education organizations have joined in producing a
booklet  of  guidelines called "Someone at School Has AIDS." The book includes
recommendations administrators,  teachers and parents  should  follow  when  a
child  or  staff  member at their school is found to have the AIDS virus.  The
booklet will be released Sept. 6.

                         BEST AND WORST TRAITS FOUND:

   The best doctors are those who strive to help patients.  The worst patients
are  those  with abrasive characters who can't accurately describe their ills.
These traits were drawn from a survey that examined how to  improve  difficult
doctor-patient  relationships.  Doctors were asked to list the traits of their
most difficult patients and their own motives for practicing medicine.

                          SEX ED CLASSES QUESTIONED:

   School sex education classes have little or no effect on  sexual  behavior,
contraception  or teen-age pregnancy,  a new survey has found.  Doctors at the
Harborview Medical Center in Seattle review  five  extensive  studies  on  the
effect  of  sex  education  classes on students.  Their findings appear in the
September issue of the journal Pediatrics.

                         NEW TECHNIQUE EXAMINES HEART:

   Doctors at the National Heart,  Lung  and  Blood  Institute  are  using  an
advanced  imaging  technique  called  nuclear magnetic resonance,  or NMR,  to
examine what happens to energy inside the cells of  living  things.  They  are
using  NMR  to  learn  more about how the heart uses its energy during certain
forms of exercise and to determine if stress tests could be used to find heart
ailments.

                          TEST PREDICTS LUNG TROUBLE:

   A new study published in the Sept.  1 issue of Annals of Internal  Medicine
shows  that  a  test  can  predict  an individual's risk of hypoxemia (trouble

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Volume  2, Number 32                                      September  4, 1989

extracting oxygen from aircraft cabins at high altitudes) during  air  travel.
Hypoxemia  can  result  in  irregular  breathing  and  respiratory and cardiac
failure.

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Volume  2, Number 32                                      September  4, 1989

===============================================================================
                      Center for Disease Control Reports
===============================================================================

                     Morbidity and Mortality Weekly Report
                           Thursday  August 31, 1989

                           Topics in Minority Health
     Motor Vehicle Crashes and Injuries in an Indian Community -- Arizona

    In 1985 and 1986, the Whiteriver Service Unit of the Indian Health Service
(IHS) investigated motor vehicle (MV) crashes* on the  White  Mountain  Apache
Reservation in eastern Arizona (Figure 1).  The reservation is located on 2600
square miles in a rural area with varied topography and climate.  In 1986, the
population  of  the  White  Mountain  Apaches was 9302 (3.6 persons per square
mile,  compared with the 1980 U.S.  average of 64.4 persons per square  mile).
More  than  3900  tribal  members  reside  in  the  community  of  Whiteriver,
approximately 180 miles northeast of Phoenix.  To determine the  incidence  of
injuries  attributable  to MV crashes and to identify risk factors amenable to
prevention strategies, the investigators reviewed White Mountain Apache Tribal
Police Department crash reports,  Arizona Department of Transportation  (ADOT)
data, and emergency department records at the Whiteriver IHS Hospital.
    For the 2-year period,  571 MV crashes were identified.  Serious injury or
death occurred in 120 (21%) crashes,  resulting in 128 hospitalizations and 24
fatalities.  The  total  annual  MV-related  fatality  rate was 129 deaths per
100,000 population; the rate was four times higher for males (206 per 100,000)
than for females (53 per 100,000).
    Two priority injury events were identified that were readily  amenable  to
prevention:  1)  crashes involving pedestrians and 2) collisions with animals.
Pedestrians were involved in only 30 (5%) crashes,  but  accounted  for  seven
(29%)  fatalities  and  17  (13%)  hospitalizations.   Ten  crashes  involving
pedestrians occurred along a 1-mile stretch of highway with  heavy  pedestrian
traffic  in the Whiteriver community.  Although posted with a 25-mile-per-hour
speed limit,  this section of  road  had  inadequate  lighting.  Eighty  (14%)
crashes  involved animals;  63 of these involved domestic livestock.  Nineteen
human injuries, but no fatalities, resulted from collisions with animals. Most
(63%) pedestrian injuries and most (77%) collisions involving animals occurred
at night.  The 461 (81%) MV  crashes  not  involving  pedestrians  or  animals
accounted for 17 fatalities and 104 hospitalizations.
    In  addition,  although  most  (73%)  of  the  crashes  occurred  on state
highways,  ADOT had records for only 58% of crashes recorded by tribal police.
Of 185 crashes that occurred on one state highway, ADOT received reports on 57
(30%).  A  third  of  all  severe  injuries and fatalities occurred along this
highway.
    Reported by: A Kane, White Mountain Apache Tribal Police Dept, Whiteriver;
DR  Olivarez,  Arizona  Dept  of  Transportation;   SJ  Englender,  MD,  State
Epidemiologist,  Arizona Dept of Health Svcs.  GL Rothfus,  Office  of  Health
Program  Research and Development,  Tucson,  C Alchesay-Nachu,  Whiteriver Svc
Unit, Whiteriver, Arizona, D Akin, Div of Environmental Health,  Indian Health
Svc,  Rockville,  Maryland.  Program Surveillance Section, Program Development
and Implementation Br,  Div of Injury Epidemiology  and  Control,  Center  for
Environmental Health and Injury Control,  CDC.

Editorial  Note:  In  1985,  the crude annual MV-related fatality rate for the
White Mountain Apaches (129 per 100,000) was three times higher than that  for

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Volume  2, Number 32                                      September  4, 1989

all  American  Indians  and  Alaskan Natives (43 per 100,000) and nearly seven
times higher than that for the total U.S.  population (19  per  100,000)  (1).
Although  American  Indians  and  Alaskan Natives are younger than the overall
U.S.  population, and MV-related fatalities occur disproportionately among the
young,  age-adjusted  fatality  rates for American Indians and Alaskan Natives
for 1981-1985 have been greater than 2 times the rate for all  U.S.  residents
and other minority groups (1; IHS, unpublished data).
    Because  MV  fatality rates correlate inversely with population density in
the United States,  the tribe's rural location may account  in  part  for  the
elevated  MV-related  death  rate.  Some researchers have attributed higher MV
fatality rates in the rural western United States to greater driving distances
in those states,  although one study found rural MV death rates to be elevated
even when the data were adjusted for distance traveled (2). Other factors that
may  contribute  to the elevated risk in rural areas include greater distances
between emergency facilities,  reduced access to major trauma centers,  travel
at  higher speeds,  and poor roads in rural areas where traffic volume is low.
In this study,  reliable data were not available to assess the contribution of
alcohol and the use/nonuse of occupant-protection devices.
    This  investigation  provided  baseline  information used to develop local
prevention  measures.  Intervention  strategies  developed  in  the  community
focused  on  MV-related  injury  events  identified  as  priorities.   Because
inadequate  lighting  was  identified  as  contributing  to  many   pedestrian
injuries,  the tribe,  IHS, and ADOT provided funding for street lights, which
were installed in December 1988 along the route where  pedestrians  were  most
frequently  injured.  To  reduce  the  number  of  crashes  involving domestic
animals,  the White Mountain Apache Tribe is developing legislation to  remove
domestic  livestock  from roadways,  require penning of animals,  and fine the
owners of stray livestock.
    ADOT allocates funds for road maintenance and highway  safety  improvement
based  on  the  frequency of MV crashes on state roads.  Because MV crashes on
the Whiteriver reservation were underreported to ADOT,  fewer state  resources
had  been  allocated  to make necessary environmental modifications.  However,
ADOT  administrators  and  design  engineers  are   using   data   from   this
investigation  to  review  the  priority  status of planned Whiteriver highway
improvements. In 1990, some two-lane roads are scheduled for expansion to four
lanes, and traffic lights in high-risk areas are to be relocated to facilitate
safer pedestrian crossings.  To more accurately document MV  injuries  on  the
reservation  and to evaluate highway safety interventions,  the White Mountain
Apache Tribal Police Department has developed an improved system of  reporting
MV crashes to ADOT.
    The Whiteriver investigation has been used as a model for
MV-related  injury prevention in the IHS Injury Prevention Program (3).  Begun
in 1987,  this community-action program  trains  selected  IHS  employees  and
tribal representatives in injury surveillance,  epidemiology, and intervention
strategies.  Thirty graduates of  the  1-year  program  are  promoting  injury
prevention in American Indian and Alaskan Native communities.

References

1.  Indian Health Service. Chart series book. Washington, DC: US Department of
Health and Human Services, Public Health Service, 1988.

2. Baker SP, Whitfield RA, O'Neill B.  Geographic variations in mortality from
motor vehicle crashes. N Engl J Med 1987;316:1384-7.

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Volume  2, Number 32                                      September  4, 1989

3.  Smith  RJ.  IHS  fellows  program  aimed  at lowering injuries,  deaths of
Indians,  Alaska Natives.  Public Health Rep 1988;103:204.

*A crash or collision involving an MV in motion,  excluding events  in  public
parking areas.

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Volume  2, Number 32                                      September  4, 1989

                        Epidemiologic Notes and Reports
                       Measles Outbreak -- Chicago, 1989

    As of August 23,  1989, 1123 confirmed cases of measles have been reported
to the Chicago Department of Health.  Information is available for 1019  (91%)
of these cases; 799 (78%) have occurred in preschool-aged children ( less than
5  years old),  including 340 (33%) children less than 16 months of age (i.e.,
too young for routine immunization).  Blacks and Hispanics have accounted  for
955 (94%) of the cases. Four measles-associated fatalities have been reported.
    Outbreak-control  activities  have  included  intensified surveillance and
lowering of the recommended age for measles vaccination to 6 months during the
outbreak,  with revaccination at age 15 months for children vaccinated  before
the first birthday.  Single-antigen measles vaccine is being used for children
before  the  first  birthday,   and  measles-mumps-rubella  vaccine  (MMR)  is
administered  to  older  children.  Seven  new  vaccination  clinics have been
established and have administered approximately 21,000 doses of vaccine; door-
--- end part 1 of 5 cut here ---

susans@seismo.css.gov (susans) (09/06/89)

In article <26876@shemp.CS.UCLA.EDU> ATW1H%ASUACAD.BITNET@oac.ucla.edu (Dr David Dodell) writes:
>--- begin part 1 of 5 cut here ---
>Volume  2, Number 32                                      September  4, 1989

	Doesn't cross posting between sci.med.aids and sci.med
	defeat the purpose of creating a sci.med.aids group?

	I think these huge five part "articles" would be better off
	in the group where people would probably be most likely to
	read them with interest--sci.med.aids.

-- 
                         Susan Scheide

                Just Another Friend of Bill's