[net.origins] New results from the laboratory

bill@utastro.UUCP (William H. Jefferys) (04/27/84)

Issue #13 of *Creation/Evolution* has just arrived, and it
contains a very interesting article by William M. Thwaites
(actually a response to an article by creationist Norman L.
Geisler in the same issue).  I thought the following quotes would
be of great interest:

	"RNA ... has all sorts of properties that we are just
	beginning to discover.  A very recent finding showed
	that not only can RNA carry coded genetic information,
	but also can carry out specific chemical reactions that
	were previously thought to be the exclusive domain of
	proteins (Lewin, 1982).  Prior to this finding, origin-
	of-life theoreticians were faced with a chicken and egg
	type of problem.  Present-day life uses nucleic acids,
	both RNA and its close relative DNA, to direct the
	synthesis of proteins.  Some of these proteins are needed
	for both DNA and protein synthesis.  While a lot of work
	remains to be done in this new area, we now know that the
	question was naive.  The claim that life couldn't have
	started with nucleic acids since they would have had no
	help from proteins seemed reasonable only until someone
	discovered that RNA can function as if it were a protein."

He also cites some experiments done by Barry Hall (1982):

	"His work has centered on the evolution of a new gene
	complex in the common bacterium *E. coli*.  He has
	taken a strain that has completely lost a gene and the
	associated genetic mechanism that regulates its
	activity.  Starting with this defective strain he has
	utilized an environment that confers an extreme selective
	advantage to any bacterium able to reinvent, so to speak,
	the missing gene and its regulatory mechanism.  Finally he
	has studied at the molecular level the "solutions" found
	by the bacterium.  The newly evolved genes naturally have
	many features in common with each other, but they also show
	a considerable amount of creativity.  Some solutions are
	elegant and some appear to be rather awkwardly complex.
	They all work, however.  If complexity were a measure of
	design, we would have to say they were all designed.  Yet
	we know the genes *evolved* in the laboratory.  Barry Hall
	did not design the new genes no matter how much the
	creationists may wish to think that he did.

	"I can think of two creationist comebacks to Hall's work.
	One would say that *E. coli* must have been designed by a 
	very clever creator to be able to evolve so well.  Such a
	response really isn't too helpful to the creationist
	cause.  The other reply would simply claim that the
	evolution of a single gene and some regulatory apparatus to
	go with it is trivial evolution "within" created kinds, and
	thus is of no real significance to the creation-evolution
	debate.  They would say that *E. coli* with the newly
	evolved genes is still *E. coli* and not a horse or a tiger.
	But if the evolution of new genes is trivial and expected
	by creationists, then all creationist arguments about
	entropy and probability are also trivial, since these
	supposedly prevent the evolution of new genes."

Thwaites remarks that Hall's articles are not easy reading, even for
many biologists.

			REFERENCES

Hall, B. B., 1982.  "Evolution of a Regulated Operon in the Laboratory."
	*Genetics* 101:335-344

Lewin, R., 1982.  "RNA Can Be a Catalyst." *Science* 218:872-874.
	(News Report).

____________________________________________________________________________
There is a lot more in this article, and I recommend it.  Creation/Evolution 
can be obtained by subscription for $9.00 per annum.  Write
		
		Creation/Evolution
		PO Box 146, Amherst Station
		Buffalo NY 14226-0146
-- 

	Bill Jefferys  8-%
	Astronomy Dept, University of Texas, Austin TX 78712   (USnail)
	{ihnp4,kpno,ctvax}!ut-sally!utastro!bill   (uucp)
	utastro!bill@ut-ngp			   (ARPANET)

bill@utastro.UUCP (William H. Jefferys) (04/28/84)

Sorry, I left out a key sentence in my quotation from William
Thwaite's article in *Creation/Evolution* #13.  The full
quotation is as follows, with the missing sentence included
between *backwards* square brackets: ]...[.

--------------------------------------------

	"RNA ... has all sorts of properties that we are just
	beginning to discover.  A very recent finding showed
	that not only can RNA carry coded genetic information,
	but also can carry out specific chemical reactions that
	were previously thought to be the exclusive domain of
	proteins (Lewin, 1982).  Prior to this finding, origin-
	of-life theoreticians were faced with a chicken and egg
	type of problem.  Present-day life uses nucleic acids,
	both RNA and its close relative DNA, to direct the
	synthesis of proteins.  Some of these proteins are needed
	for both DNA and protein synthesis.  ]The old puzzle was
	where the first proteins came from to help DNA and RNA
	direct protein synthesis.[  While a lot of work
	remains to be done in this new area, we now know that the
	question was naive.  The claim that life couldn't have
	started with nucleic acids since they would have had no
	help from proteins seemed reasonable only until someone
	discovered that RNA can function as if it were a protein."
-- 

	Bill Jefferys  8-%
	Astronomy Dept, University of Texas, Austin TX 78712   (USnail)
	{ihnp4,kpno,ctvax}!ut-sally!utastro!bill   (uucp)
	utastro!bill@ut-ngp			   (ARPANET)