bill@utastro.UUCP (William H. Jefferys) (04/27/84)
Issue #13 of *Creation/Evolution* has just arrived, and it contains a very interesting article by William M. Thwaites (actually a response to an article by creationist Norman L. Geisler in the same issue). I thought the following quotes would be of great interest: "RNA ... has all sorts of properties that we are just beginning to discover. A very recent finding showed that not only can RNA carry coded genetic information, but also can carry out specific chemical reactions that were previously thought to be the exclusive domain of proteins (Lewin, 1982). Prior to this finding, origin- of-life theoreticians were faced with a chicken and egg type of problem. Present-day life uses nucleic acids, both RNA and its close relative DNA, to direct the synthesis of proteins. Some of these proteins are needed for both DNA and protein synthesis. While a lot of work remains to be done in this new area, we now know that the question was naive. The claim that life couldn't have started with nucleic acids since they would have had no help from proteins seemed reasonable only until someone discovered that RNA can function as if it were a protein." He also cites some experiments done by Barry Hall (1982): "His work has centered on the evolution of a new gene complex in the common bacterium *E. coli*. He has taken a strain that has completely lost a gene and the associated genetic mechanism that regulates its activity. Starting with this defective strain he has utilized an environment that confers an extreme selective advantage to any bacterium able to reinvent, so to speak, the missing gene and its regulatory mechanism. Finally he has studied at the molecular level the "solutions" found by the bacterium. The newly evolved genes naturally have many features in common with each other, but they also show a considerable amount of creativity. Some solutions are elegant and some appear to be rather awkwardly complex. They all work, however. If complexity were a measure of design, we would have to say they were all designed. Yet we know the genes *evolved* in the laboratory. Barry Hall did not design the new genes no matter how much the creationists may wish to think that he did. "I can think of two creationist comebacks to Hall's work. One would say that *E. coli* must have been designed by a very clever creator to be able to evolve so well. Such a response really isn't too helpful to the creationist cause. The other reply would simply claim that the evolution of a single gene and some regulatory apparatus to go with it is trivial evolution "within" created kinds, and thus is of no real significance to the creation-evolution debate. They would say that *E. coli* with the newly evolved genes is still *E. coli* and not a horse or a tiger. But if the evolution of new genes is trivial and expected by creationists, then all creationist arguments about entropy and probability are also trivial, since these supposedly prevent the evolution of new genes." Thwaites remarks that Hall's articles are not easy reading, even for many biologists. REFERENCES Hall, B. B., 1982. "Evolution of a Regulated Operon in the Laboratory." *Genetics* 101:335-344 Lewin, R., 1982. "RNA Can Be a Catalyst." *Science* 218:872-874. (News Report). ____________________________________________________________________________ There is a lot more in this article, and I recommend it. Creation/Evolution can be obtained by subscription for $9.00 per annum. Write Creation/Evolution PO Box 146, Amherst Station Buffalo NY 14226-0146 -- Bill Jefferys 8-% Astronomy Dept, University of Texas, Austin TX 78712 (USnail) {ihnp4,kpno,ctvax}!ut-sally!utastro!bill (uucp) utastro!bill@ut-ngp (ARPANET)
bill@utastro.UUCP (William H. Jefferys) (04/28/84)
Sorry, I left out a key sentence in my quotation from William Thwaite's article in *Creation/Evolution* #13. The full quotation is as follows, with the missing sentence included between *backwards* square brackets: ]...[. -------------------------------------------- "RNA ... has all sorts of properties that we are just beginning to discover. A very recent finding showed that not only can RNA carry coded genetic information, but also can carry out specific chemical reactions that were previously thought to be the exclusive domain of proteins (Lewin, 1982). Prior to this finding, origin- of-life theoreticians were faced with a chicken and egg type of problem. Present-day life uses nucleic acids, both RNA and its close relative DNA, to direct the synthesis of proteins. Some of these proteins are needed for both DNA and protein synthesis. ]The old puzzle was where the first proteins came from to help DNA and RNA direct protein synthesis.[ While a lot of work remains to be done in this new area, we now know that the question was naive. The claim that life couldn't have started with nucleic acids since they would have had no help from proteins seemed reasonable only until someone discovered that RNA can function as if it were a protein." -- Bill Jefferys 8-% Astronomy Dept, University of Texas, Austin TX 78712 (USnail) {ihnp4,kpno,ctvax}!ut-sally!utastro!bill (uucp) utastro!bill@ut-ngp (ARPANET)