hes@ecsvax.UUCP (03/06/84)
<> It was mentioned that one of the big new application areas of
computation in biology is the storage and processing of DNA sequence
data. (Really nucleic acid sequences, but the data is almost all on
DNA rather than RNA.)
A recent book which covers much of this field (and which has broader
coverage than the title suggests) is:
Statistical Analysis of DNA Sequence Data
edited by B. S. Weir, 1983
published by Marcel Dekker, Inc., NY
The chapters are written by different authors and are:
1. Determination of DNA Fragment Size from Gel Electrophoresis Mobility
2. Computers and DNA Sequences: A Natural Combination
3. The Role of Models in the Analysis of Molecular Genetic Data, with
Particular Reference to Restriction Fragment Data
4. Statistical Analysis of Restriction Enzyme Map Data and Nucleotide
Sequence Data
5. Analysis of Variation in Related DNA Sequences
6. Inferring Evolutionary Trees from DNA Sequences
7. Convergent Evolution and Nonparametric Inferences from Restriction
Data and DNA Sequences
8. The Number of Polymorphic DNA Clones Required to Map the Human
Genome
9. Use of Restriction Fragment Polymorphisms as Genetic Markers
I wrote the first chapter, and will discuss this topic in this
newsgroup in the near future.
--henry schaffer ncsu genetics