[net.med] Partially Hydrogenated Oils

sebb@pyuxss.UUCP (S Badian) (01/18/84)

	Has anyone seen any studies about the ill effects
of partially hydrogenated oils? My mother told me that they
are bad for us but she didn't tell me what they do. They
would be pretty tough to avoid since they're in everything.
	Also, I know I saw a lot of discussion about milk
and lactose intolerance. Has anyone seen anything about
the linking of homogenized milk to hardening of the arteries?
				Sharon Badian

sanders@menlo70.UUCP (01/25/84)

Partially hydrogenated oils should have nearly the same nutritional and
disease-causing properties as partially saturated fats, i.e.  not so
good for you.

Oils are hydrogenated for a variety of reasons.  One effect of
hydrogenating an oil is to raise it's melting point.  For examples,
look at safflower oil (very unsaturated, liquid even in the
refrigerator), "cocoa butter" (a relatively rare saturated oil of plant
origin), margarine (usually made from "partially hydrogenated corn
oil"), and dairy butter (oils are completely saturated).

All oils of animal origin are completely saturated.  Most plant oils
are less than completely saturated.  Saturated oils (fats) have been
linked to high blood cholesterol levels (and therefor heart disease)
and cancer of the colon.

Saturation is a measure of how many of the carbon-carbon bonds in the
long hydrocarbon chains of fats are single or double bonds.  A
completely saturated fat has no double bonds.  A mono-unsaturated fat
(e.g. olive oil), has one double bond.  "Polyunsaturated" fats have
more than one double bond.  Bubbling reactive hydrogen gas
("hydrogenating") reduces the number of double bonds in the oil, i.e.
it saturates the oil.

seifert@ihuxl.UUCP (01/25/84)

Yes, partially hydrogenated oils are bad for you. But first,
what *is* a "partially hydrogenated oil"?

A saturated oil/fat is a carbon chain with all the 'extra'
spots taken up by hydrogen atoms.  An unsaturated oil/fat
is missing some hydrogen atoms, the carbons forming double bonds
instead.


	 H H H H H H H H		 H     H     H
	 | | | | | | | |		 |     |     |
	-C-C-C-C-C-C-C-C-		-C-C=C-C-C=C-C-
	 | | | | | | | |		 | | | | | | |
	 H H H H H H H H		 H H H H H H H
	
	   saturated			   unsaturated
	

Long chains tend to be solid, short chains tend to be liquid.
Saturated chains tend to be solid, unsaturated chains tend to be liquid.

Butter is 4-18 carbons long, beef fat is 14-18 carbons long.

To make an unsaturated oil more solid, they bubble hydrogen
through it.  This creates a "new" fat, one not found in nature.

[No, I don't know why it doesn't create the same saturated (or
less unsaturated) fat as found in nature.]

"In fact, a recent elaborate statistical analysis of the incidence of
heart disease and the consumption of hydrogenated fats in England
has shown a dramatic and detailed correlation between the two.
Where margarine and solid vegatable shortenings were used in
significant quantities, the rate of heart attack was always higher
than where they weren't."  [1]

"Recently, there has been a growing number of reports of an
increased incidence of cancer in patients who take a high
percentage of unsaturated and polyunsaturated oils. This
was noted by physicians whose patients showed an unusual
frequency of malignant melonama, a rapidly fatal form of
skin cancer.  Inquiry into their dietary habits showed that
in each case there had recently been an enthusiastic switch
to vegetable fats and oils instead of butter. [2] Other
research supports this impression. [3] "

Quotes from _D_i_e_t & _N_u_t_r_i_t_i_o_n, _a _h_o_l_i_s_t_i_c _a_p_p_r_o_a_c_h, by
Rudolph Ballentine, M.D.

[1] Thomas, L. Mortality from arteriosclerotic disease
    and comsumption of hydrogenated oils and fats.
    _B_r_i_t _J _P_r_e_v _S_o_c _M_e_d 29: 82-90, 1975

[2] Mackie, B. Malignant melanoma and diet. _M_e_d _J _A_u_s_t_r_a_l_i_a,
    May 1974, p 810 (letter)

[3] West, C. and Redgrave, T. Reservations on the use of
    polyunstaurated fats in human nutrition. _A_m _L_a_b Jan 1975 p28
-- 
		_____
	       /_____\		from the flying doghouse of
	      /_______\			Snoopy
		|___|	
	    ____|___|_____	    ihnp4!ihuxl!seifert

ee161abe@sdccs5.UUCP (Doug Salot) (01/29/84)

I'm interested in the responce to ihuxl!seifet's recent posting
concerning saturated vs unsaturated fats in the diet.  I have
always been under the impression that saturated fats were the
ones to stay clear of.  I believe there have been studies which
have shown that high intake of saturated fats (primarily from
animal sources) increased one's chance of coronary artery
disease.  The references of ihuxl!siefer seem to imply that
the switch from saturated (animal) to unsaturated (plant) fats
is detremental.
Also, I believe that the difference between partailly hydrogenated
oils and naturally occuring unsaturated oils comes from the
process of hydrogenation.  Nature uses enzymes to catalyze the
hydrogenation reaction.  This tends to stick the H's on in a
precise fasion (I believe the 'd' optical isomer is prevalent in
nature), whereas industrial hydrogenation uses a metal catalyst
(Nickel, I think) which sticks H's on any old way.  I think
the consequence is that industrially hydrogenated oils are
not fully metabolized.
Can somebody shoot me down or back me up on any of this?

- Doug Salot	..!sdcsvax!sdccs5!ee161abe

sdyer@bbncca.ARPA (Steve Dyer) (01/31/84)

Regarding commercially hydrogenated fats as being detrimental because
they contain unnatural isomers:

Because the hydrogenation of unsaturated fats involves the conversion of
double bonds to single bonds, there can be no problem with the production
of unwanted isomers during the process of hydrogenation.  That is,
carbons cannot rotate around a pair of double bonds, and so for any
molecule asymmetric around a double bond, there are two steric possibilities:

X      H                                X      X
 \    /                                  \    / 
  C==C          (trans)                   C==C          (cis)
 /    \                                  /    \ 
H      X                                H      H

Adding hydrogen, however, destroys this asymmetry, regardless of whether
it's done by an enzyme or by a catalyst like nickel.  You end up with

X-CH-CH-X
    2  2

regardless of which isomer you started out with.  Saturated fats are
"bad" because they predispose a population towards increased cholesterol
levels, which have been implicated in arteriosclerosis and heart disease.
As far as your body is concerned, "Crisco" is no worse than lard, given equal
saturation levels.
-- 
/Steve Dyer
decvax!bbncca!sdyer
sdyer@bbncca