[net.med] Malaria and sickle cell

jca@drutx.UUCP (ArnsonJC) (08/27/85)

It is not the HgbS that is responsible for malaria "immunity". It is
due to lack of the Duffy Blood Group System genes, both a and b.
[ie. Fya-, Fyb-].  It just happens that both the HgbS genes and
Duffy {or should I say lack of} genes are both found in the same
segment of the population. {Blacks}

				jill

werner@aecom.UUCP (Craig Werner) (08/29/85)

> It is not the HgbS that is responsible for malaria "immunity". It is
> due to lack of the Duffy Blood Group System genes, both a and b.
> [ie. Fya-, Fyb-].  It just happens that both the HgbS genes and
> Duffy {or should I say lack of} genes are both found in the same
> segment of the population. {Blacks}
> 				jill

	The Duffy Blood Groups antigens (the ones most different between whites
and Blacks) is the receptor for Vivax Malaria.
	The HbS/HbA mutation is for Plasmodium falcifurim malaria.  They are
two different diseases, but both called malaria.

Incidentally, I have been told that I switched one of my HbSs with an HbA. If
you saw an apparent contradiction, it was an unfortunate typo.  -- CW.
-- 
				Craig Werner
				!philabs!aecom!werner
		"The world is just a straight man for you sometimes"