[net.med] Electrosleep

mmm@weitek.UUCP (Mark Thorson) (10/16/85)

Has anyone else ever heard of electrosleep?  Supposedly it is a method for
tranquilizing via the use of a low frequency signal applied to electrodes
on the neck.  I have heard that it is widely used in Europe and the Soviet
Union in lieu of drugs, but the FDA (or drug industry lobbying) has blocked
its use here.

Does the technique exist?  What are the parameters of the signal used?
Are there any side-effects?  Do you have references to literature on the
theory and use of the technique (I'd really like to get the manual for one
of these machines)?

Mark Thorson  (...!cae780!weitek!mmm)

larry@kitty.UUCP (Larry Lippman) (11/03/85)

> Has anyone else ever heard of electrosleep?  Supposedly it is a method for
> tranquilizing via the use of a low frequency signal applied to electrodes
> on the neck.  I have heard that it is widely used in Europe and the Soviet
> Union in lieu of drugs, but the FDA (or drug industry lobbying) has blocked
> its use here.
> 
> Does the technique exist?  What are the parameters of the signal used?
> Are there any side-effects?  Do you have references to literature on the
> theory and use of the technique (I'd really like to get the manual for one
> of these machines)?

	I happened to have conducted some research studies with one of these
devices in the late 60's when, as an EE, I held a research position at a
medical school.  The particular device was - believe it or not - manufactured
by Hewlett-Packard as their 3380B Electroanesthesia Instrument.  The device
consisted of a dual sine wave - a fixed 100 Hz - plus a variable 700 Hz to
10 kHz.  Maximum output current was 100 mA with a maximum open-circuit voltage
of 100 volts RMS; although I never used the instrument to anywhere near full
output power.
	This instrument was marketed by H-P as an experimental device NOT to be
used for humans; it was considered to be suitable for veterinary clinical use.
The particular studies I ran were on dogs (anti-vivisectionists send flames to
/dev/null).  The purpose of my evaluation was to see if this was a suitable
device to be used for medical research studies on animals (to avoid using any
chemically-induced anesthesia); if it appeared promising for that purpose, then
there was to be some CAREFUL consideration for human use.
	There were two electrode schemes in use: (1) one metal electrode
placed on the hard palate, with the other electrode held against the occiptal
region of the scalp; (2) two subcutaneous needle electrodes placed in opposite
temporal regions of the head.  All of my studies were conducted using the
latter method.
	Studies were conducted on about 15 dogs, with rather poor results.
I won't go into details here - but that was a real trip since there was no
anesthetic premedication used on the dogs.  Some dogs would induce okay, while
others never experienced any analgesia or anesthesia, irregardless of current
setting or electrode placement.  We used a physiological recording system after
anesthesia was induced to record arterial pressure, venous pressure, intra-
cranial presure, ECG, EEG, and cardiac output using dye injection.  In addition,
we took blood gases and pH.  So the process was carefully studied and the data
evaluated by several people.  There were many undesireable side-effects in
those dogs where anesthesia was induced including, but not limited to: excess
salivation, bradycardia, reduced cardiac output, cardiac arrhythmias, etc.
After the study, we concluded that the instrument was of no reliable value for
animal anesthesia in a research environment, and certainly had a LONG way to
go before human consideration.
	I have been out of the academic research environment since 1970, so I
have lost touch with any current developments in electroanesthia.  I will
provide two literature references from my files:

	"Clinical Effects of Anesthesia Produced by Alternating Electrical
	Current" by C. E. Short, ``Journal of the International Anesthesia
	Research Society'', September-October 1965

	"The Cardiovascular Effects of Cranially-Impressed Electric Currents
	of Anesthetic Intensity" by Wood, Powers, et al, ``Journal of the
	International Anesthesia Research Society'', May-June 1964

I will provide further information upon request, including a copy of the H-P
sales literature (probably a collector's item by now :-) ).
	I have not kept current with developments in the field of electro-
anesthesia, and do not claim to be an expert on the topic.  However, I did
have some firsthand experience once-upon-a-time, which is what I am sharing
with the Net.

===  Larry Lippman @ Recognition Research Corp., Clarence, New York        ===
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