werner@aecom.UUCP (09/16/86)
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Intracavernous Drug-Induced Erections in the Management of Male
Erectile Dysfunction: Experience with 100 Patients
Sidi, Abraham Ami, et. al.
J. Urology 1986;135:704-706.
Abstract:
A total of 100 men with organic impotence underwent a trial of
intracavernous drug-induced erections with a mixture of papaverine
(25 mg/mL) and phentolamine (0.8 mg/mL). The response rates, that is
functional erections, were 100% in patients with neurogenic impotence,
65.7% in those with vasculogenic impotence, 90% in the undetermined
group. Of the responders 79.5% elected to practice self-injection as a
method to restore erectile function. The dose required to obtain
functional erections in the purely neurogenic impotence group was
significantly lower than that required in other groups. Complications
were few and included four patients with sustained erections that
required intervention. Intracavernous injection of vasoactive drugs
appears to have promising value in the treatment and differential
diagnosis of erectile dysfunction.
--
Craig Werner (MD/PhD '91)
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